The woolly spider monkey, or muriqui, is one of the most threatened primate species in the world. Because of deforestation in their natural habitat—the Atlantic coastal forests of southeastern Brazil—the muriquis are confined to less than 3 percent of their original range. As of 1987, there were only a dozen forest fragments known to support a total muriqui population of about 500. As of 1998, at least 20 forests are known to support at least 1,000 muriquis. This book traces the natural history of the muriqui from its scientific discovery in 1806 to its current, highly endangered status.

Karen Strier provides a case study of this scientifically important primate species by balancing field research and ecological issues. Through her accessible presentation, readers gain a broad understanding of primate behavior and tropical conservation.

In a remarkable synthesis of the research of the last two decades, a leading developmental neuroscientist provides psychologists with a sophisticated introduction to the brain—the system that underpins the functions that they study.

In clear terms, with ample illustrations, Joan Stiles explains the complexities of genetic variation and transcription, and the variable paths of neural development, from embryology through early childhood. She describes early developmental processes from gene expression to physiology to behavior. Sections on clinical correlations show the consequences for later physiological, neurological, or psychological disturbances in neural development.

As Stiles shows, brain development is far more complex and dynamic than is often assumed in debates about nature vs. nurture, nativism vs. cultural learning. Inherited and experienced factors interact constantly in an ever-changing organism. The key question is, what developmental processes give rise to particular structures or mechanisms?

A landmark of synthesis and interdisciplinary illumination, The Fundamentals of Brain Development will enrich discussion of developmental processes and more rigorously define the terms that are central to psychological debates.

Here is a brief but comprehensive tour of the physiology of vision, guided by one of the grand masters of the discipline. Offering first a solid grounding in structure and function, the book emphasizes those areas that the author considers to be of most significance in current research. Much attention is given to the role of vision in circadian timekeeping, the development of the visual system, the effect of aging on the eye, and the provocative questions of perception and illusion.

An eminently readable text, Focus on Vision will more than satisfy the needs of students in ophthalmology, optometry, physiological optics, biology, psychology, and art. It is fully illustrated and contains lists of references and further reading. The questions at the end of each chapter may be used to test understanding or simply to excite discussion.

In 1645 the Japanese samurai Musashi Miamoto wrote A Book of Five Rings, which described the attitudes necessary for individual success. Though he was a swordsman, his book was not limited to combat but addressed the much broader question of how to achieve excellence in life through study, discipline, and planning. It is still avidly read in Japan today. Arthur Kornberg’s book is a modern-day Book of Five Rings that replaces the medium of swordsmanship with that of biochemistry, particularly enzymology. As Kornberg describes his successive research problems, the challenges they presented, and the ultimate accomplishments that resulted, he provides us with a primer in the strategies needed to do scientific work of great significance. Moreover, these strategies are played out in the context of solving some of the great biochemical problems of the twentieth century.

The ability to manipulate and alter DNA fired a revolution that forever changed the nature of biology. Arthur Kornberg is a primary architect of that revolution, arguably one of the two or three most important biologists of this time. Prior to Kornberg, genetic information and later DNA were imbued by biologists with an almost vitalistic aura. Kornberg demonstrated that DNA is a molecule synthesized by enzymes, like all other chemical constituents of the cell. More important, he trained a school of scientists who focused on and discovered many of the enzymatic activities that act on DNA. It is these enzymes in particular that allow modern “genetic engineering.”

For the Love of Enzymes does not describe a single lucky or hard-won accomplishment. Rather, it is the story of thirty years of decisive campaigns, nearly all of which led to insights of major significance. In relating his story, Kornberg never avoids the difficult question of “why”: why he felt classical nutritional studies had reached a plateau, why he turned to enzymology as a discipline in which the important answers would be found, and why he believes the study of enzymes will grow ever more important as we face the new scientific frontier of brain function.

This book will challenge students of biology and chemistry at all levels who want to do important work rather than simply follow popular trends. It will also delight and inform readers who wish to understand how “real” science is done, and to learn of the values that guide one of our greatest researchers.

Winner of the Margaret W. Rossiter History of Women in Science Prize

A new history uncovers the crucial role women played in the great transformations of medical science and health care that accompanied the Italian Renaissance.

In Renaissance Italy women played a more central role in providing health care than historians have thus far acknowledged. Women from all walks of life—from household caregivers and nurses to nuns working as apothecaries—drove the Italian medical economy. In convent pharmacies, pox hospitals, girls’ shelters, and homes, women were practitioners and purveyors of knowledge about health and healing, making significant contributions to early modern medicine.

Sharon Strocchia offers a wealth of new evidence about how illness was diagnosed and treated, whether by noblewomen living at court or poor nurses living in hospitals. She finds that women expanded on their roles as health care providers by participating in empirical work and the development of scientific knowledge. Nuns, in particular, were among the most prominent manufacturers and vendors of pharmaceutical products. Their experiments with materials and techniques added greatly to the era’s understanding of medical care. Thanks to their excellence in medicine urban Italian women had greater access to commerce than perhaps any other women in Europe.

Forgotten Healers provides a more accurate picture of the pursuit of health in Renaissance Italy. More broadly, by emphasizing that the frontlines of medical care are often found in the household and other spaces thought of as female, Strocchia encourages us to rethink the history of medicine.

    First, Do No Harm shows how health care professionals, with the best intentions of providing excellent, holistic health care, can nonetheless perpetuate violence against vulnerable patients. The essays investigate the need to rethink contemporary healthcare practices in ways that can bring the art and science of medicine back into sorely needed balance.
    These ground-breaking studies by noted scholars question commonly held assumptions in contemporary healthcare that underlie oppressive power dynamics and even violence for patients and their families. The contributors discuss such topics as women and violence, life-support technologies, and healthcare professionals’ own experiences as patients. First, Do No Harm opens the discourse for reaching new understandings, from reassessing the meaning of "quality of life" to questioning the appropriateness of the very language used by healthcare professionals. It will be welcomed by healthcare workers and by scholars in nursing, medicine, and the allied health sciences.

Americans are understandably concerned about the runaway costs of medical care and the fact that one citizen out of seven is without health insurance coverage. Solving these problems is a top priority for the Clinton administration, but as Victor Fuchs shows, the task is enormously complex. In this book Fuchs, America's foremost health economist, provides the reader with the necessary concepts, facts, and analyses to comprehend the complicated issues of health policy. He shows why health care reform that benefits society as a whole will unavoidably burden certain individuals and groups.

Fuchs addresses such central questions as cost containment, managed competition, technology assessment, poverty and health, children's health, and national health insurance. The future of U.S. health policy, he argues, is tightly linked to three basic questions; First, how can we disengage health insurance from employment? Second, how can we tame technological change in health care? And finally how can we cope with the runaway medical costs of an aging society?

Medical care prices in the United States are not only the most expensive in the world, but there are wide variations in what physicians are paid. Doctors at the frontlines of medical care who manage complex conditions argue that they receive disproportionately lower fees than physicians performing services such as minor surgeries and endoscopies. Fixing Medical Prices goes to the heart of the U.S. medical pricing process: to a largely unknown yet influential committee of medical organizations affiliated with the American Medical Association that advises Medicare. Medicare’s ready acceptance of this committee’s recommendations typically sets off a chain reaction across the entire American health care system.

For decades, the U.S. policymaking structure for pricing has reflected the influence of physician organizations. What Miriam Laugesen’s rich analysis shows is how these organizations navigate the arcane and complex work of this advisory committee. Contradicting the story of a profession in political decline, Fixing Medical Prices demonstrates that the power of physician organizations has simply become more subtle.

Laugesen’s investigation into the exorbitant cost of American medical care will be of interest to those who follow the politics of health care policy, the influence of interest groups on rate setting, and the medical profession’s past and future role in our health care system.

So many women who do everything right to stay healthy still wind up with breast cancer, heart disease, or osteoporosis. In The Fragile Wisdom, Grazyna Jasienska provides an evolutionary perspective on the puzzle of why disease prevention among women is so frustratingly difficult. Modern women, she shows, are the unlucky victims of their own bodies’ conflict of interest between reproductive fitness and life-long health.

The crux of the problem is that women’s physiology has evolved to facilitate reproduction, not to reduce disease risk. Any trait—no matter how detrimental to health in the post-reproductive period—is more likely to be preserved in the next generation if it increases the chance of giving birth to offspring who will themselves survive to reproductive age. To take just one example, genes that produce high levels of estrogen are a boon to fertility, even as they raise the risk of breast cancer in mothers and their daughters.

Jasienska argues that a mismatch between modern lifestyles and the Stone Age physiology that evolution has bequeathed to every woman exacerbates health problems. She looks at women’s mechanisms for coping with genetic inheritance and at the impact of environment on health. Warning against the false hope gene therapy inspires, Jasienska makes a compelling case that our only avenue to a healthy life is prevention programs informed by evolutionary understanding and custom-fitted to each woman’s developmental and reproductive history.

The forensic entomologist turns a dispassionate, analytic eye on scenes from which most people would recoil--human corpses in various stages of decay, usually the remains of people who have met a premature end through accident or mayhem. To Lee Goff and his fellow forensic entomologists, each body recovered at a crime scene is an ecosystem, a unique microenvironment colonized in succession by a diverse array of flies, beetles, mites, spiders, and other arthropods: some using the body to provision their young, some feeding directly on the tissues and by-products of decay, and still others preying on the scavengers.

Using actual cases on which he has consulted, Goff shows how knowledge of these insects and their habits allows forensic entomologists to furnish investigators with crucial evidence about crimes. Even when a body has been reduced to a skeleton, insect evidence can often provide the only available estimate of the postmortem interval, or time elapsed since death, as well as clues to whether the body has been moved from the original crime scene, and whether drugs have contributed to the death.

An experienced forensic investigator who regularly advises law enforcement agencies in the United States and abroad, Goff is uniquely qualified to tell the fascinating if unsettling story of the development and practice of forensic entomology.

Consider two polar images of the same medical condition: the pale and fragile Camille ensconced on a chaise in a Victorian parlor, daintily coughing a small spot of blood onto her white lace pillow, and a wretched poor man in a Bowery flophouse spreading a dread and deadly infection. Now Katherine Ott chronicles how in one century a romantic, ambiguous affliction of the spirit was transformed into a disease that threatened public health and civic order. She persuasively argues that there was no constant identity to the disease over time, no “core” tuberculosis.

What we understand today as pulmonary tuberculosis would have been largely unintelligible to a physician or patient in the late nineteenth century. Although medically the two terms described the same disease of the lungs, Ott shows that “tuberculosis” and “consumption” were diagnosed, defined, and treated distinctively by both lay and professional health workers. Ott traces the shift from the pre-industrial world of 1870, in which consumption was conceived of primarily as a middle-class malaise that conferred virtue, heightened spirituality, and gentility on the sufferer, to the post-industrial world of today, in which tuberculosis is viewed as a microscopic enemy, fought on an urban battleground and attacking primarily the outcast poor and AIDS patients.

Ott’s focus is the changing definition of the disease in different historical eras and environments. She explores its external trappings, from the symptoms doctors chose to notice (whether a pale complexion or a tubercle in a dish) to the significance of the economic and social circumstances of the patient. Emphasizing the material culture of disease—medical supplies, advertisements for faraway rest cures, outdoor sick porches, and invalid hammocks—Ott provides insight into people’s understanding of illness and how to combat it. Fevered Lives underscores the shifting meanings of consumption/tuberculosis in an extraordinarily readable cultural history.

Barbara Stafford is a pioneering art historian whose research has long helped to bridge the divide between the humanities and cognitive sciences. In A Field Guide to a New Meta-Field, she marshals a distinguished group of thinkers to forge a ground-breaking dialogue between the emerging brain sciences, the liberal arts, and social sciences.

Stafford’s book examines meaning and mental function from this dual experimental perspective. The wide-ranging essays included here—from Frank Echenhofer’s foray into shamanist hallucinogenic visions to David Bashwiner’s analysis of emotion and danceability—develop a common language for implementing programmatic and institutional change. Demonstrating how formerly divided fields are converging around shared issues, A Field Guide to a New Meta-Field maps a high-level, crossdisciplinary adventure from one of our leading figures in visual studies.

No other book in the field so fully combines vivid clinical examples, specific details of technique, and mature perspectives on both effectively functioning families and those seeking therapy. The views and strategies of a master clinician are presented here in such clear and precise form that readers can proceed directly from the book with comparisons and modifications to suit their own styles and working situations.

Salvador Minuchin presents six chapter-length transcripts of actual family sessions—two devoted to ordinary families who are meeting their problems with relative success; four concerned with families seeking help. Accompanying each transcript is the author’s running interpretation of what is taking place, laying particular stress on the therapist’s tactics and maneuvers.

These lively sessions are interpreted in a brilliant theoretical analysis of why families develop problems and what it takes to set them right. The author constructs a model of an effectively functioning family and defines the boundaries around its different subsystems, whether parental, spouse, or sibling. He discusses ways in which families adapt to stress from within and without, as they seek to survive and grow.

Dr. Minuchin describes methods of diagnosing or “mapping” problems of the troubled family and determining appropriate therapeutic goals and strategies. Different situations, such as the extended family, the family with a parental child, and the family in transition through death or divorce, are examined. Finally, the author explores the dynamics of change, examining the variety of restructuring operations that can be employed to challenge a family and to change its basic patterns.

Here is a brief and authoritative account of human physical growth, beautifully written by one of the world's foremost experts. In Fetus into Man Professor Tanner tells the story of growth in language that is both accessible to the nonbiologist and acceptable to the biologist.

The book begins with the basics of growth: cell division, hormonal control and differential growth of body tissues. It then builds on these basics to provide a picture of individual growth--from the fetus in utero to the development of sex differences at puberty. Tanner pays special attention along the way to the psychological and social problems faced by children who mature either too soon or too late, and he concludes with a full description of the major growth disorders and current methods of treatment.

Fetus into Man will be an important reference for parents, educators, students of development, and indeed anyone who must deal with the growing child.

Teen-aged girls hate their bodies and diet obsessively, or so we hear. News stories and reports of survey research often claim that as many as three girls in five are on a diet at any given time, and they grimly suggest that many are “at risk” for eating disorders. But how much can we believe these frightening stories? What do teenagers mean when they say they are dieting?

Anthropologist Mimi Nichter spent three years interviewing middle school and high school girls—lower-middle to middle class, white, black, and Latina—about their feelings concerning appearance, their eating habits, and dieting. In Fat Talk, she tells us what the girls told her, and explores the influence of peers, family, and the media on girls’ sense of self. Letting girls speak for themselves, she gives us the human side of survey statistics.

Most of the white girls in her study disliked something about their bodies and knew all too well that they did not look like the envied, hated “perfect girl.” But they did not diet so much as talk about dieting. Nichter wryly argues—in fact some of the girls as much as tell her—that “fat talk” is a kind of social ritual among friends, a way of being, or creating solidarity. It allows the girls to show that they are concerned about their weight, but it lessens the urgency to do anything about it, other than diet from breakfast to lunch. Nichter concludes that if anything, girls are watching their weight and what they eat, as well as trying to get some exercise and eat “healthfully” in a way that sounds much less disturbing than stories about the epidemic of eating disorders among American girls.

Black girls, Nichter learned, escape the weight obsession and the “fat talk” that is so pervasive among white girls. The African-American girls she talked with were much more satisfied with their bodies than were the white girls. For them, beauty was a matter of projecting attitude (“’tude”) and moving with confidence and style.

Fat Talk takes the reader into the lives of girls as daughters, providing insights into how parents talk to their teenagers about their changing bodies. The black girls admired their mothers’ strength; the white girls described their mothers’ own “fat talk,” their fathers’ uncomfortable teasing, and the way they and their mothers sometimes dieted together to escape the family “curse”—flabby thighs, ample hips. Moving beyond negative stereotypes of mother–daughter relationships, Nichter sensitively examines the issues and struggles that mothers face in bringing up their daughters, particularly in relation to body image, and considers how they can help their daughters move beyond rigid and stereotyped images of ideal beauty.

At the most prestigious preparatory schools in the United States, the children of educators are referred to as “faculty brats.” Though generally lacking the privilege of the institution’s wealthy students, faculty brats enjoy access to the school’s extensive grounds and facilities and are part of everyday campus life.

Dominic Bucca’s art teacher mother married his music teacher stepfather twice, and the young boy wondered if the union might be twice as strong as a result. Instead, this faculty brat quickly discovered that the marriage was twice as flawed. When Dominic was nine years old, his stepfather began sexually abusing him in the faculty housing attached to the boys’ dorm his parents oversaw. Years later, he found escape by reaching out to his biological father, and learned to split his life between two realities.

For nearly twenty-five years, Bucca hid the secret of his step­father’s abuse from his mother and sisters. When he decided to tell, hoping to prevent his stepfather from continuing to teach young boys, Bucca discovered the limits of both his family and the legal system.

The largest unmet health need in this country—and potentially the most costly—is for dental care; meeting this need would strain existing personnel and facilities beyond capacity. This book reports an experiment in delivering dental care by means that are not traditional but preserve the high standards that have been achieved by American dentistry.

At the Forsyth Dental Center in Boston, Massachusetts, graduate dental hygienists received additional training in the administration of local anesthesia, drilling decayed teeth, and filling them. The program was designed to prepare dental auxiliaries to undertake restorative treatment under the direct supervision of a dentist who assumes ultimate responsibility for planning treatment, assessing the quality of performance, and assuring the patient's well-being.

The Forsyth experiment yielded information on the competence of auxiliaries trained in this fashion, on patient acceptance, on the efficiency of various patterns of practice, and on the potential economic effects of delivering care in this way. The results of the study are bound to stir controversy, but they cannot be ignored by anyone who cares about a major problem in health care.