Social scientists study complex phenomena about which they often propose intricate hypotheses tested with linear-interactive or multiplicative terms. While interaction terms are hardly new to social science research, researchers have yet to develop a common methodology for using and interpreting them. Modeling and Interpreting Interactive Hypotheses in Regression Analysis provides step-by-step guidance on how to connect substantive theories to statistical models and how to interpret and present the results.
"Kam and Franzese is a must-have for all empirical social scientists interested in teasing out the complexities of their data."
---Janet M. Box-Steffensmeier, Ohio State University
"Kam and Franzese have written what will become the definitive source on dealing with interaction terms and testing interactive hypotheses. It will serve as the standard reference for political scientists and will be one of those books that everyone will turn to when helping our students or doing our work. But more than that, this book is the best text I have seen for getting students to really think about the importance of careful specification and testing of their hypotheses."
---David A. M. Peterson, Texas A&M University
"Kam and Franzese have given scholars and teachers of regression models something they've needed for years: a clear, concise guide to understanding multiplicative interactions. Motivated by real substantive examples and packed with valuable examples and graphs, their book belongs on the shelf of every working social scientist."
---Christopher Zorn, University of South Carolina
"Kam and Franzese make it easy to model what good researchers have known for a long time: many important and interesting causal effects depend on the presence of other conditions. Their book shows how to explore interactive hypotheses in your own research and how to present your results. The book is straightforward yet technically sophisticated. There are no more excuses for misunderstanding, misrepresenting, or simply missing out on interaction effects!"
---Andrew Gould, University of Notre Dame
Cindy D. Kam is Assistant Professor, Department of Political Science, University of California, Davis.
Robert J. Franzese Jr. is Associate Professor, Department of Political Science, University of Michigan, and Research Associate Professor, Center for Political Studies, Institute for Social Research, University of Michigan.
For datasets, syntax, and worksheets to help readers work through the examples covered in the book, visit: www.press.umich.edu/KamFranzese/Interactions.html
For seven years, Paul Lockhart’s A Mathematician’s Lament enjoyed a samizdat-style popularity in the mathematics underground, before demand prompted its 2009 publication to even wider applause and debate. An impassioned critique of K–12 mathematics education, it outlined how we shortchange students by introducing them to math the wrong way. Here Lockhart offers the positive side of the math education story by showing us how math should be done. Measurement offers a permanent solution to math phobia by introducing us to mathematics as an artful way of thinking and living.
In conversational prose that conveys his passion for the subject, Lockhart makes mathematics accessible without oversimplifying. He makes no more attempt to hide the challenge of mathematics than he does to shield us from its beautiful intensity. Favoring plain English and pictures over jargon and formulas, he succeeds in making complex ideas about the mathematics of shape and motion intuitive and graspable. His elegant discussion of mathematical reasoning and themes in classical geometry offers proof of his conviction that mathematics illuminates art as much as science.
Lockhart leads us into a universe where beautiful designs and patterns float through our minds and do surprising, miraculous things. As we turn our thoughts to symmetry, circles, cylinders, and cones, we begin to see that almost anyone can “do the math” in a way that brings emotional and aesthetic rewards. Measurement is an invitation to summon curiosity, courage, and creativity in order to experience firsthand the playful excitement of mathematical work.
The Fifth edition of this classic textbook includes a solutions manual. Extensive supplemental instructor resources are forthcoming in the Fall of 2022.
Mechanical Vibration: Theory and Application presents comprehensive coverage of the fundamental principles of mechanical vibration, including the theory of vibration, as well as discussions and examples of the applications of these principles to practical engineering problems. The book also addresses the effects of uncertainties in vibration analysis and design and develops passive and active methods for the control of vibration. Many example problems with solutions are provided. These examples as well as compelling case studies and stories of real-world applications of mechanical vibration have been carefully chosen and presented to help the reader gain a thorough understanding of the subject.Humans have always viewed the heavens with wonder and awe. The skies have inspired reflection on the vastness of space, the wonder of creation, and humankind’s role in the universe. In just over one hundred years, science has moved from almost total ignorance about the actual distances to the stars and earth’s place in the galaxy to our present knowledge about the enormous size, mass, and age of the universe. We are reaching the limits of observation, and therefore the limits of human understanding. Beyond lies only our imagination, seeded by the theories of physics. In Measuring the Cosmos, science writers David and Matthew Clark tell the stories of both the well-known and the unsung heroes who played key roles in these discoveries. These true accounts reveal ambitions, conflicts, failures, as well as successes, as the astonishing scale and age of the universe were finally established. Few areas of scientific research have witnessed such drama in the form of ego clashes, priority claims, or failed (or even falsified) theories as that resulting from attempts to measure the universe. Besides giving credit where long overdue, Measuring the Cosmos explains the science behind these achievements in accessible language sure to appeal to astronomers, science buffs, and historians.
In an agential realist account, the world is made of entanglements of “social” and “natural” agencies, where the distinction between the two emerges out of specific intra-actions. Intra-activity is an inexhaustible dynamism that configures and reconfigures relations of space-time-matter. In explaining intra-activity, Barad reveals questions about how nature and culture interact and change over time to be fundamentally misguided. And she reframes understanding of the nature of scientific and political practices and their “interrelationship.” Thus she pays particular attention to the responsible practice of science, and she emphasizes changes in the understanding of political practices, critically reworking Judith Butler’s influential theory of performativity. Finally, Barad uses agential realism to produce a new interpretation of quantum physics, demonstrating that agential realism is more than a means of reflecting on science; it can be used to actually do science.
The past decade has been characterized by remarkable advances in meteorological observation, computing techniques, and data-visualization technology. However, the benefit of these advances can only be fully realized with the introduction of a systematic, applied approach to meteorological education that allows well-established theoretical concepts to be applied to modernized observational and numerical datasets.
The classic book on the state’s unique geology, now back in print!
Have you ever wondered how the Mississippi River was formed? Or why shark teeth have been found in the Iron Range of the Upper Midwest? Towering mountain ranges, explosive volcanoes, expansive glaciers, and long-extinct forms of both land and sea life were important parts of Minnesota’s ancient history. Today the evidence of this remarkable heritage is revealed in the state’s rocky outcroppings, stony soils, and thousands of lakes.
Minnesota’s Geology provides a history of the past 3.5 billion years in the area’s development. In accessible language, Minnesota-based geologists Richard W. Ojakangas and Charles L. Matsch tell the story of the state’s past and offer a guide for those who want to read geological history firsthand from the rocks and landscapes of today. The book’s four sections give a short introduction to geology and Minnesota’s place in geologic history; a historic timeline; a look at the metallic minerals, nonmetals, and water present today; and a geologic picture of today’s Minnesota arranged in five geographical regions. This book is both a wonderful source of information for rock hounds and the perfect backpacking companion for tourists and outdoor enthusiasts. Lavishly illustrated with color and black-and-white photographs, as well as extensive graphs and maps, Minnesota’s Geology will inform and delight for years to come."This is certainly one of the finest books about the geology of any state in the United States. It is written at a level that should satisfy the visitor, the student, and even most professionals." American Scientist"A stunning guide . . . Minnesota’s Geology will be as valuable to the rock hound or student as it is to a trained geologist." Duluth News-Tribune"Minnesota’s Geology sets a standard of excellence for books about the geology of a region. . . . an unusually well-written and well-balanced book." Science Books and FilmsRichard W. Ojakangas and Charles L. Matsch are professors in the Department of Geological Sciences at the University of Minnesota, Duluth.Intended for the general reader, Missouri Geology is a well-illustrated introduction to the fascinating geology of Missouri.
This is the story of a Chinese doctor, his book, and the creatures that danced within its pages. The Monkey and the Inkpot introduces natural history in sixteenth-century China through the iconic Bencao gangmu (Systematic materia medica) of Li Shizhen (1518–1593).
The encyclopedic Bencao gangmu is widely lauded as a classic embodiment of pre-modern Chinese medical thought. In the first book-length study in English of Li’s text, Carla Nappi reveals a “cabinet of curiosities” of gems, beasts, and oddities whose author was devoted to using natural history to guide the application of natural and artificial objects as medical drugs. Nappi examines the making of facts and weighing of evidence in a massive collection where tales of wildmen and dragons were recorded alongside recipes for ginseng and peonies.
Nappi challenges the idea of a monolithic tradition of Chinese herbal medicine by showing the importance of debate and disagreement in early modern scholarly and medical culture. The Monkey and the Inkpot also illuminates the modern fate of a book that continues to shape alternative healing practices, global pharmaceutical markets, and Chinese culture.
Mice in the Freezer, Owls on the Porch is in many ways a love story—about a quiet scientist and his flamboyant wife, but also about their passions for hunting, for wild lands, and for the grouse and raptor species that they were instrumental in saving from destruction.
From the papers and letters of Frederick and Frances Hamerstrom, the reminiscences of contemporaries, and her own long friendship with this extraordinary couple who were her neighbors, Helen Corneli draws an intimate picture of Fran and "Hammy" from childhood through the genesis and maturation of a romantic, creative, and scientific relationship. Following the Hamerstroms as they give up a life of sophisticated convention and comfort for the more "civilized" (as Aldo Leopold would have it) pleasures of living and conducting on-the-spot research into diminishing species, Corneli captures the spirit of the Hamerstroms, their profession, and the natural and human environments in which they worked. A nuanced account of the labors, adventures, and achievements that distinguished the Hamerstroms over the years—and that inspired a generation of naturalists—this book also provides a dramatic account of conservation history over the course of the twentieth century, particularly in Wisconsin during the eventful years from the 1920s through the 1970s.
The memoir of a scientist and the wild silk moths he studiesBiologist Michael Collins has been studying wild silk moths since he was a boy. This family — which includes the largest and most colorful of the North American moths — led Collins into a long career as a scientist, and has provided him with significant insights into the process by which new species evolve. Moth Catcher is Collins’s engaging account of his development as a scientist and of his groundbreaking research. The canyon and pass environments of the American West offer a setting in which, since the last Ice Age, organisms have adapted to new surroundings and where many have formed new species. Collins has discovered in the Sierra Nevada that geneticists call a “hybrid zone” where two species interbreed. This hybrid zone is unusual because both sexes are fertile, unlike lab-bred hybrids between the same silk moth species. Collins explains how such hybrid populations serve as laboratories in nature where the process of speciation can be observed and studied. This book offers a fascinating view into the work of a field scientist and the ways that evolution continues to operate around us. Collins’s colorful accounts of his fieldwork will delight any reader who loves the outdoors and is captivated by the diversity and interrelations of the life forms found there. And his passion for his research and the fragile, exquisite creatures that he studies will inspire a new appreciation of the wonders of the natural world and the myriad life forms that occupy it.
First published in 1974 as a companion volume to Darwin on Man by Howard E. Gruber, Paul Barrett’s transcriptions of Darwin’s M and N notebooks served to shed new light on the evolutionist’s methods and motivation.
According to Stephen Jay Gould in the New York Times Book Review, “Darwin kept [these notebooks] primarily in 1838, when he was 29 years old. In them, he recorded his early conviction of evolutionary continuity between humans and all other animals. . . . These notebooks display all the features of humanistic intellect that his detractors denied. We find erudition in his comments on Plato, Locke, Hume, Adam Smith, Whewell, Burke, Montaigne, Lessing and Spencer. . . . We appreciate an artistic bent in his delight with nature and her prophet Wordsworth. . . . We grasp the breadth of his bold attempt to clothe all human thought and behaviour in a new evolutionary garb. . . . Charles Darwin was reconstructing the world and he knew exactly what he was doing.”
Measures of Success is a practical, hands-on guide to designing, managing, and measuring the impacts of community-oriented conservation and development projects. It presents a simple, clear, logical, and yet comprehensive approach to developing and implementing effective programs, and can help conservation and development practitioners use principles of adaptive management to test assumptions about their projects and learn from the results.
The book presents a systematic approach to improving the focus, effectiveness, and efficiency of projects, with specific guidelines and advice on:
The text is developed in eight chapters that follow the structure of a planning process from conception to completion, with the chapters linked by four scenarios that serve as teaching case studies throughout the book. Examples from these scenarios illustrate the processes and tools discussed, and each scenario case study is presented in its entirety in an appendix to the volume. The approach has been developed and field tested by practitioners working in many different projects in Latin America, Africa, and Asia, and their experience and input ensure that the guide is both practical and useful.
Measures of Success is the only work of its kind currently available, and represents an invaluable resource for field-based practitioners, project managers, and local community leaders, as well as for international NGO staff, college and university teachers and students, researchers, and government officials.
Under the Clean Water Act, development that results in the permanent destruction of wetlands must, in most cases, be mitigated by the creation of a new wetland or the restoration of a degraded one. In recent years, the concept of "mitigation banking" has emerged. Rather than require developers to create and maintain wetlands on their own on a quid pro quo basis, mitigation banking allows them to pay for wetlands that have been created and maintained properly by others to compensate for their damage.
The contributors to this volume provide an overview of mitigation banking experience in the United States, examine the key issues and concerns -- from providing assurances to determining the value of credits -- and describe the practice of developing and operating a mitigation bank. Topics include:
Humans are terrestrial animals, and our capacity to see and understand the importance and vulnerability of life in the sea has trailed our growing ability to harm it. While conservation biologists are working to address environmental problems humans have created on land, loss of marine biodiversity, including extinctions and habitat degradation, has received much less attention. At the same time, marine sciences such as oceanography and fisheries biology have largely ignored issues of conservation.
Marine Conservation Biology brings together for the first time in a single volume, leading experts from around the world to apply the lessons and thinking of conservation biology to marine issues. Contributors including James M. Acheson, Louis W. Botsford, James T. Carlton, Kristina Gjerde, Selina S. Heppell, Ransom A. Myers, Julia K. Parrish, Stephen R. Palumbi, and Daniel Pauly offer penetrating insights on the nature of marine biodiversity, what threatens it, and what humans can and must do to recover the biological integrity of the world's estuaries, coastal seas, and oceans.
Sections examine: distinctive aspects of marine populations and ecosystems; threats to marine biological diversity, singly and in combination; place-based management of marine ecosystems; the often-neglected human dimensions of marine conservation.
Marine Conservation Biology breaks new ground by creating the conceptual framework for the new field of marine conservation biology -- the science of protecting, recovering, and sustainably using the living sea. It synthesizes the latest knowledge and ideas from leading thinkers in disciplines ranging from larval biology to sociology, making it a must-read for research and teaching faculty, postdoctoral fellows, and graduate and advanced undergraduate students (who share an interest in bringing conservation biology to marine issues). Likewise, its lucid scientific examinations illuminate key issues facing environmental managers, policymakers, advocates, and funders concerned with the health of our oceans.
Stretching from the craggy reaches of the Pocono Mountains to the rolling farmlands of Lancaster County, Pennsylvania, sprawling east across the Delaware River basin and New Jersey’s coastal plain Atlantic beaches—here is a land of rich historical, cultural, and environmental diversity. Few other locales in the United States have as many varied habitats, each with its own distinctive vegetation and wildlife. The nature lover in the Delaware Valley can travel from ocean, across barrier-beaches, salt-water and fresh-water marshes, pine barrens, deciduous woodlands and fields, to mountains, all in a few hours.
Marsh, Meadow, Mountain, a combination tour guide and ecological primer, is written for the thousands of people in the area with an interest in natural history or for those seeking alternative recreational activities. Each chapter, written by an experienced naturalist intimately familiar with one of the seven major ecosystems, introduces the reader to the dynamic interrelationships in nature, the interactions between a particular habitat and its inhabitants, and its plants and wildlife. Over 135 locations are described including the Pocono Mountains, the Pine Barrens, Stone Harbor, Delaware Water Gap National Recreation Area, Ridley Creek State Park, Tyler Arboretum, and Tinicum National Environmental Center, which in any season can provide fascinating viewing opportunities depending upon your interests. Each site also includes addresses, directions, trail maps, artistic drawings, and a suggested reading list.
Marsh, Meadow, Mountain conveys both a sense of fun and learning and, ultimately, will instill in the reader a special intimacy with the Delaware Valley’s precious wild places.
Did you know . . . ?
These and many more amazing facts await the curious traveler in The Michigan Roadside Naturalist, J. Alan and Margaret B. Holman's captivating guide to the natural treasures of Michigan. A perfect accompaniment to the classic Michigan Trees and The Forests of Michigan, this user-friendly guide offers a Who's Who of the geology, biology, and archaeology of the Great Lakes State, as well as highway adventures along the state's major routes.
The book begins with an educational yet accessible tour of important points in Michigan's natural and archaeological history, followed by seven road trips based on commonly traveled state routes, moving from south to north in the Lower Peninsula and east to west in the Upper Peninsula. Readers can proceed directly to the road trips or familiarize themselves with the state's treasure trove of fascinating features before embarking. Either way, an informative and fun odyssey awaits the passionate naturalist, amateur or otherwise.
J. Alan Holman is Curator Emeritus of Vertebrate Paleontology at the Michigan State University Museum and Emeritus Professor of Geology and Zoology at Michigan State University. Margaret B. Holman is Research Associate at Michigan State University Museum and Department of Anthropology, Michigan State University.
Seeking a closer connection with nature than the manicured lawns of suburbia, naturalist Fred Gehlbach and his family built a house on the edge of a wooded ravine in Central Texas in the mid-1960s. On daily walks over the hills, creek hollows, and fields of the ravine, Gehlbach has observed the cycles of weather and seasons, the annual migrations of birds, and the life cycles of animals and plants that also live in the ravine.
In this book, Gehlbach draws on thirty-five years of journal entries to present a composite, day-by-day almanac of the life cycles of this semiwild natural island in the midst of urban Texas. Recording such events as the hatching of Eastern screech owl chicks, the emergence of June bugs, and the first freeze of November, he reminds us of nature's daily, monthly, and annual cycles, from which humans are becoming ever more detached in our unnatural urban environments. The long span of the almanac also allows Gehlbach to track how local and even global developments have affected the ravine, from scars left by sewer construction to an increase in frost-free days probably linked to global warming.
This long-term record of natural cycles provides one of only two such baseline data sets for North America. At the same time, the book is an eloquent account of one keen observer's daily interactions with his wild and human neighbors and of the lessons in connectedness and the "play of life" that they teach.
Much like Vladimir Lenin, his onetime rival for the leadership of the Bolshevik party during its formative years, Alexander Bogdanov (1873–1928) was a visionary. In two science fiction novels set on Mars, Bogdanov imagined a future in which the workers of the world, liberated from capitalist exploitation, create a “physiological collective” that rejuvenates and unites its members through regular blood exchanges. But Bogdanov was not merely a dreamer. He worked tirelessly to popularize and realize his vision, founding the first research institute devoted to the science of blood transfusion.
In A Martian Stranded on Earth, the first broad-based book on Bogdanov in English, Nikolai Krementsov examines Bogdanov’s roles as revolutionary, novelist, and scientist, presenting his protagonist as a coherent thinker who pursued his ideas in a wide range of venues. Through the lens of Bogdanov’s involvement with blood studies on one hand, and of his fictional and philosophical writings on the other, Krementsov offers a nuanced analysis of the interactions between scientific ideas and societal values.
How computer animation technologies became vital visualization tools in the life sciences
Who would have thought that computer animation technologies developed in the second half of the twentieth century would become essential visualization tools in today’s biosciences? This book is the first to examine this phenomenon. Molecular Capture reveals how popular media consumption and biological knowledge production have converged in molecular animations—computer simulations of molecular and cellular processes that immerse viewers in the temporal unfolding of molecular worlds—to produce new regimes of seeing and knowing.
Situating the development of this technology within an evolving field of historical, epistemological, and political negotiations, Adam Nocek argues that molecular animations not only represent a key transformation in the visual knowledge practices of life scientists but also bring into sharp focus fundamental mutations in power within neoliberal capitalism. In particular, he reveals how the convergence of the visual economies of science and entertainment in molecular animations extends neoliberal modes of governance to the perceptual practices of scientific subjects. Drawing on Alfred North Whitehead’s speculative metaphysics and Michel Foucault’s genealogy of governmentality, Nocek builds a media philosophy well equipped to examine the unique coordination of media cultures in this undertheorized form of scientific media. More specifically, he demonstrates how governmentality operates across visual practices in the biosciences and the popular mediasphere to shape a molecular animation apparatus that unites scientific knowledge and entertainment culture.
Ultimately, Molecular Capture proposes that molecular animation is an achievement of governmental design. It weaves together speculative media philosophy, science and technology studies, and design theory to investigate how scientific knowledge practices are designed through media apparatuses.
Even after 150 years, Darwin’s theory of evolution by natural selection is irresistibly compelling. But how can this idea—in which competition prevails—be consistent with all that we know about the thoroughly cooperative nature of life at the genetic and cellular level? This book reconciles these discrepancies.
Assembling a set of general principles, authors Kenneth Weiss and Anne Buchanan build a comprehensive, unified theory that applies on the evolutionary time scale but also on the developmental and ecological scales where daily life is lived, and cells, organisms, and species interact. They present this story through a diversity of examples spanning the fundamental challenges that organisms have faced throughout the history of life. This shows that even very complex traits can be constructed simply, based on these principles. Although relentless competitive natural selection is widely assumed to be the primary mover of evolutionary change, The Mermaid’s Tale shows how life more generally works on the basis of cooperation. The book reveals that the focus on competition and cooperation is largely an artifact of the compression of time—a distortion that dissolves when the nature and origins of adapted life are viewed primarily from developmental and evolutionary time scales.
The idea of evolution: it fascinates some of us, disturbs others, and leaves only a very few people indifferent. In a major new interpretation of evolutionary theory, Michael Ruse pinpoints the common source of this attraction and discomfort. A renowned writer on evolutionary theory and its history, Ruse has long been sensitive to the fact that many people--and not simply religious enthusiasts--find something deeply troubling about much of what passes for science in evolutionary circles. What causes this tension, he finds in his search of evolutionism's 250-year history, is the intimate relationship between evolution and the secular ideology of progress.
Ubiquitous in Darwin's time, the idea of an unceasing improvement in life insinuated its way into evolutionary theory from the first. In interviews with today's major figures in evolutionary biology--including Stephen Jay Gould, Edward O. Wilson, Ernst Mayr, and John Maynard Smith--and in an intimate look at the discoveries and advances in the history and philosophy of science, Ruse finds this belief just as prevalent today--however it might be denied or obscured. His book traces the delicate line between those who argue that science is and must be objective and those who deem science a "social construction" in the fashion of religion or the rest of culture. It offers an unparalleled account of evolutionary theory, from popular books to museums to the most complex theorizing, at a time when its status as science is under greater scrutiny than ever before.
With the recent Sokal hoax--the publication of a prominent physicist's pseudo-article in a leading journal of cultural studies--the status of science moved sharply from debate to dispute. Is science objective, a disinterested reflection of reality, as Karl Popper and his followers believed? Or is it subjective, a social construction, as Thomas Kuhn and his students maintained? Into the fray comes Mystery of Mysteries, an enlightening inquiry into the nature of science, using evolutionary theory as a case study.
Michael Ruse begins with such colorful luminaries as Erasmus Darwin (grandfather of Charles) and Julian Huxley (brother of novelist Aldous and grandson of T. H. Huxley, "Darwin's bulldog" ) and ends with the work of the English game theorist Geoffrey Parker--a microevolutionist who made his mark studying the mating strategies of dung flies--and the American paleontologist Jack Sepkoski, whose computer-generated models reconstruct mass extinctions and other macro events in life's history. Along the way Ruse considers two great popularizers of evolution, Richard Dawkins and Stephen Jay Gould, as well as two leaders in the field of evolutionary studies, Richard Lewontin and Edward O. Wilson, paying close attention to these figures' cultural commitments: Gould's transplanted Germanic idealism, Dawkins's male-dominated Oxbridge circle, Lewontin's Jewish background, and Wilson's southern childhood. Ruse explicates the role of metaphor and metavalues in evolutionary thought and draws significant conclusions about the cultural impregnation of science. Identifying strengths and weaknesses on both sides of the "science wars," he demonstrates that a resolution of the objective and subjective debate is nonetheless possible.
Making Sense of Evolution explores contemporary evolutionary biology, focusing on the elements of theories—selection, adaptation, and species—that are complex and open to multiple possible interpretations, many of which are incompatible with one another and with other accepted practices in the discipline. Particular experimental methods, for example, may demand one understanding of “selection,” while the application of the same concept to another area of evolutionary biology could necessitate a very different definition.
Spotlighting these conceptual difficulties and presenting alternate theoretical interpretations that alleviate this incompatibility, Massimo Pigliucci and Jonathan Kaplan intertwine scientific and philosophical analysis to produce a coherent picture of evolutionary biology. Innovative and controversial, Making Sense of Evolution encourages further development of the Modern Synthesis and outlines what might be necessary for the continued refinement of this evolving field.
In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology.
A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.
Born by mistake, or connivance, to struggling parents in a small Lancashire cotton town in 1903, an uninspired Darlington inadvertently escaped the obscurity of farming life and rose instead, against all odds, to become within a few short years the world's greatest expert on chromosomes, and one of the most penetrating biological thinkers of the twentieth century. Harman follows Darlington's path from bleak prospects to world fame, showing how, within the most miniscule of worlds, he sought answers to the biggest questions--how species originate, how variation occurs, how Nature, both blind and foreboding, random and insightful, makes her way from deep past to unknown future. But Darlington did not stop there: Chromosomes held within their tiny confines untold, dark truths about man and his culture. This passionate conviction led the once famed Darlington down a path of rebuke, isolation, and finally obscurity.
As The Man Who Invented the Chromosome unfolds Darlington's forgotten tale--the Nazi atrocities, the Cold War, the crackpot Lysenko, the molecular revolution, eugenics, Civil Rights, the welfare state, the changing views of man's place in nature, biological determinism--all were interconnected. Just as Darlington's work provoked him to ask questions about the link between biology and culture, his life raises fundamental questions about the link between science and society.
At a time when the complete human genome has been sequenced and when seemingly every week feature news stories describe genes that may be responsible for personality, intelligence, even happiness, Michel Morange gives us a book that demystifies the power of modern genetics. The Misunderstood Gene takes us on an easily comprehensible tour of the most recent findings in molecular biology to show us how—and if—genes contribute to biological processes and complex human behaviors.
As Morange explains, if molecular biologists had to designate one category of molecules as essential to life, it would be proteins and their multiple functions, not DNA and genes. Genes are the centerpiece of modern biology because they can be modified. But they are only the memory that life invented so that proteins could be efficiently reproduced. Morange shows us that there is far more richness and meaning in the structure and interactions of proteins than in all the theoretical speculations on the role of genes.
The Misunderstood Gene makes it clear that we do not have to choose between rigid genetic determinism and fearful rejection of any specific role for genes in development or behavior. Both are true, but at different levels of organization. Morange agrees with those who say “we are not in our genes.” But he also wants us to understand that we are not without our genes, either. We are going to have to make do with them, and this book will show us how.
What do biologists want? If, unlike their counterparts in physics, biologists are generally wary of a grand, overarching theory, at what kinds of explanation do biologists aim? How will we know when we have “made sense” of life? Such questions, Evelyn Fox Keller suggests, offer no simple answers. Explanations in the biological sciences are typically provisional and partial, judged by criteria as heterogeneous as their subject matter. It is Keller’s aim in this bold and challenging book to account for this epistemological diversity—particularly in the discipline of developmental biology.
In particular, Keller asks, what counts as an “explanation” of biological development in individual organisms? Her inquiry ranges from physical and mathematical models to more familiar explanatory metaphors to the dramatic contributions of recent technological developments, especially in imaging, recombinant DNA, and computer modeling and simulations.
A history of the diverse and changing nature of biological explanation in a particularly charged field, Making Sense of Life draws our attention to the temporal, disciplinary, and cultural components of what biologists mean, and what they understand, when they propose to explain life.
Freshwater turtles and goldfish can survive for several days without oxygen, some diving turtles for several months; hibernating animals can exist without food for long periods; others can survive extreme conditions such as desiccation, freezing, and thawing. These creatures are, in effect, self-sustaining life-support systems, with a mysterious ability to regulate their own metabolisms.
These capabilities raise important questions, which Hochachka and Guppy explore in this seminal new book. What mechanisms turn down (or off) cell metabolism and other cell functions? How does an animal such as an opossum know when to activate mechanisms for slowing or stopping tissue and organ functions? How does it know when to turn them on again? How extensive is metabolic arrest as a defense against harsh environmental conditions? Can we decipher universal principles of metabolic arrest from available data? The lessons to be learned are of potentially great interest to clinicians, because the authors provide a theoretical framework in which to organize an attack on the all-too-practical problem of protecting tissues against hypoxia. Areas that may be influenced include research on cardiac arrest, strokes, acute renal failure, liver ischemia, lung injury, respiratory defense syndrome, claudication, shock, and organ transplant. Investigation of other metabolic arrest mechanisms may be similarly useful in both clinical and agricultural fields.
This is a pioneering book of great use to biomedical/clinical researchers and to biologists, biochemists, and physiologists generally.
In the years after the Revolutionary War, the fledgling republic of America was viewed by many Europeans as a degenerate backwater, populated by subspecies weak and feeble. Chief among these naysayers was the French Count and world-renowned naturalist Georges-Louis Leclerc de Buffon, who wrote that the flora and fauna of America (humans included) were inferior to European specimens.
Thomas Jefferson—author of the Declaration of Independence, U.S. president, and ardent naturalist—spent years countering the French conception of American degeneracy. His Notes on Virginia systematically and scientifically dismantled Buffon’s case through a series of tables and equally compelling writing on the nature of his home state. But the book did little to counter the arrogance of the French and hardly satisfied Jefferson’s quest to demonstrate that his young nation was every bit the equal of a well-established Europe. Enter the giant moose.
The American moose, which Jefferson claimed was so enormous a European reindeer could walk under it, became the cornerstone of his defense. Convinced that the sight of such a magnificent beast would cause Buffon to revise his claims, Jefferson had the remains of a seven-foot ungulate shipped first class from New Hampshire to Paris. Unfortunately, Buffon died before he could make any revisions to his Histoire Naturelle, but the legend of the moose makes for a fascinating tale about Jefferson’s passion to prove that American nature deserved prestige.
In Mr. Jefferson and the Giant Moose, Lee Alan Dugatkin vividly recreates the origin and evolution of the debates about natural history in America and, in so doing, returns the prize moose to its rightful place in American history.
In Modern Nature,Lynn K. Nyhart traces the emergence of a “biological perspective” in late nineteenth-century Germany that emphasized the dynamic relationships among organisms, and between organisms and their environment. Examining this approach to nature in light of Germany’s fraught urbanization and industrialization, as well the opportunities presented by new and reforming institutions, she argues that rapid social change drew attention to the role of social relationships and physical environments in rendering a society—and nature—whole, functional, and healthy.
This quintessentially modern view of nature, Nyhart shows, stood in stark contrast to the standard naturalist’s orientation toward classification. While this new biological perspective would eventually grow into the academic discipline of ecology, Modern Nature locates its roots outside the universities, in a vibrant realm of populist natural history inhabited by taxidermists and zookeepers, schoolteachers and museum reformers, amateur enthusiasts and nature protectionists.
Probing the populist beginnings of animal ecology in Germany, Nyhart unites the history of popular natural history with that of elite science in a new way. In doing so, she brings to light a major orientation in late nineteenth-century biology that has long been eclipsed by Darwinism.
Making Nature Whole is a seminal volume that presents an in-depth history of the field of ecological restoration as it has developed in the United States over the last three decades. The authors draw from both published and unpublished sources, including archival materials and oral histories from early practitioners, to explore the development of the field and its importance to environmental management as well as to the larger environmental movement and our understanding of the world.
Considering antecedents as varied as monastic gardens, the Scientific Revolution, and the emerging nature-awareness of nineteenth-century Romantics and Transcendentalists, Jordan and Lubick offer unique insight into the field's philosophical and theoretical underpinnings. They examine specifically the more recent history, including the story of those who first attempted to recreate natural ecosystems early in the 20th century, as well as those who over the past few decades have realized the value of this approach not only as a critical element in conservation but also as a context for negotiating the ever-changing relationship between humans and the natural environment.
Making Nature Whole is a landmark contribution, providing context and history regarding a distinctive form of land management and giving readers a fascinating overview of the development of the field. It is essential reading for anyone interested in understanding where ecological restoration came from or where it might be going.
Pioneered in the late 1980s, the concept of macroecology—a framework for studying ecological communities with a focus on patterns and processes—revolutionized the field. Although this approach has been applied mainly to terrestrial ecosystems, there is increasing interest in quantifying macroecological patterns in the sea and understanding the processes that generate them. Taking stock of the current work in the field and advocating a research agenda for the decades ahead, Marine Macroecology draws together insights and approaches from a diverse group of scientists to show how marine ecology can benefit from the adoption of macroecological approaches.
Divided into three parts, Marine Macroecology first provides an overview of marine diversity patterns and offers case studies of specific habitats and taxonomic groups. In the second part, contributors focus on process-based explanations for marine ecological patterns. The third part presents new approaches to understanding processes driving the macroecolgical patterns in the sea. Uniting unique insights from different perspectives with the common goal of identifying and understanding large-scale biodiversity patterns, Marine Macroecology will inspire the next wave of marine ecologists to approach their research from a macroecological perspective.
Biological membranes have been under intensive investigation for several decades. Despite very great experimental challenges, membranes are at last beginning to reveal their secrets. In this book, leading investigators of membrane structure and function report on progress in three related fields: specialization of membrane regions, asymmetry in transport properties, and differentiation of cell faces in epithelia.
"Specialization at the Molecular Level" is the subject of the first section; in it, the authors consider such problems as the biogenesis of membranes, the geometry of protein-lipid relationships, and the physical properties of membrane receptor-sites. In the second section, "Asymmetry in Transport," such topics as the sodium-potassium pump, proton translocation, and anion transport are covered. The last section is entitled "Polar Faces in Epithelia" and deals with the complex properties of ion transport across the complex membrane environment maintained by surfaces such as the renal tubular epithelia.
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