Aging and cancer may be manifestations of genetic, or epigenetic, changes in somatic cells. Through research, laboratory analysis of these related processes has become possible. Cells can be removed from the body, kept warm in laboratory glassware, nourished by artificial solutions, and studied for years, or even decades. Two types of cultures have emerged: Primary cultures, grown from cells obtained directly from living animals, may grow well for generations, but ultimately cease to divide. Established cultures, on the other hand, may grow and divide indefinitely. It is a striking fact that most, if not all, established cultures consist of cells that are heteroploid, having an abnormal chromosome complement that may include structural rearrangements as well as abnormalities of chromosome number.

Most established cultures are also neoplastic on behavior and morphology—in this, they resemble cancers—and established cultures are, in fact, often grown from cancer cells. Interest in the role of chromosomes in neoplasia has recently been overshadowed by an emphasis on tumor viruses. This book should reawaken the former interest. It will also arouse new interest in the role of epigenetic mechanisms of animal cells, in contrast to the classic genetic processes. As Dr. John Littlefield writes: “The relationship between the overcoming of senescence, the appearance of heteroploidy, and the acquisition of neoplastic qualities is not yet clear, but it is of such great theoretical and practical importance as to demand attention and new ideas.”

Between 1777 and 1816, botanical expeditions crisscrossed the vast Spanish empire in an ambitious project to survey the flora of much of the Americas, the Caribbean, and the Philippines. While these voyages produced written texts and compiled collections of specimens, they dedicated an overwhelming proportion of their resources and energy to the creation of visual materials. European and American naturalists and artists collaborated to manufacture a staggering total of more than 12,000 botanical illustrations. Yet these images have remained largely overlooked—until now.

In this lavishly illustrated volume, Daniela Bleichmar gives this archive its due, finding in these botanical images a window into the worlds of Enlightenment science, visual culture, and empire. Through innovative interdisciplinary scholarship that bridges the histories of science, visual culture, and the Hispanic world, Bleichmar uses these images to trace two related histories: the little-known history of scientific expeditions in the Hispanic Enlightenment and the history of visual evidence in both science and administration in the early modern Spanish empire. As Bleichmar shows, in the Spanish empire visual epistemology operated not only in scientific contexts but also as part of an imperial apparatus that had a long-established tradition of deploying visual evidence for administrative purposes.

Everyone with a professional interest in the flora of Texas will welcome this checklist of the vascular plants. This comprehensive list also includes crops, persistent perennials, and naturalized plants and encompasses over 1,000 changes to the previous (Hatch, 1990) checklist. The authors have arranged this checklist phylogenetically by classes following the Cronquist system.

Several features make this checklist especially useful. Chief among them is the relative synonymy (name history). An extensive index makes current classification and correct nomenclature readily accessible, while the botanical bibliography is the most extensive ever compiled for Texas. The authors also note which plants have been listed as threatened or endangered by the Texas Organization of Endangered Species, which are designated as Federal Noxious Weeds, and which have been chosen as state tree, flower, fruit, etc. by the Texas Legislature.

Texas has about one hundred twenty native species and subspecies of snakes, fifteen of which are venomous. Since 1950, Texans have turned to the Poisonous Snakes of Texas pamphlet series published by the Texas Parks and Wildlife Department for help in identifying these snakes and for expert advice on preventing and treating snakebite. Venomous Snakes of Texas, a thoroughly revised and updated edition of Poisonous Snakes, carries on this tradition as a one-stop, all-you-need-to-know guide to Texas's rattlesnakes, copperheads, cottonmouths, and coral snakes.

In this authoritative field guide, you'll find:

• Full-color photographs and a county-by-county distribution map for each species.
• Each species' common and scientific name, description, look-alikes, and a summary sketch of its habitat, behavior, reproduction, venom characteristics, predator-prey relationships, and fossil record.
• Up-to-date advice on recognizing venomous snakes and preventing and treating snakebite, both at home and in the field.
• A glossary of terms and an extensive bibliography.

A special feature of this guide is an expanded treatment of the ecological and evolutionary context in which venomous snakes live, which supports Price's goal "to lessen the hatred and fear and to increase the understanding, the respect, and even the appreciation with which venomous snakes should be regarded."

In creatures as different as crickets and scorpions, mole rats and elephants, there exists an overlooked channel of communication: signals transmitted as vibrations through a solid substrate. Peggy Hill summarizes a generation of groundbreaking work by scientists around the world on this long understudied form of animal communication.

Beginning in the 1970s, Hill explains, powerful computers and listening devices allowed scientists to record and interpret vibrational signals. Whether the medium is the sunbaked savannah or the stem of a plant, vibrations can be passed along from an animal to a potential mate, or intercepted by a predator on the prowl. Vibration appears to be an ancient means of communication, widespread in both invertebrate and vertebrate taxa. Hill synthesizes in this book a flowering of research, field studies documenting vibrational signals in the wild, and the laboratory experiments that answered such questions as what adaptations allowed animals to send and receive signals, how they use signals in different contexts, and how vibration as a channel might have evolved.

Vibrational Communication in Animals promises to become a foundational text for the next generation of researchers putting an ear to the ground.

During the past ten years, several theories have been proposed on the origin of the diversity of antibodies. George P. Smith presents a critical study of these theories in this detailed treatment of immunological problems from the point of view of molecular genetics.

Mr. Smith uses a new and simplifying approach to this long-standing controversy. By a comprehensive computerized analysis of antibody amino acid sequences (particularly the myeloma proteins), the author traces their evolution and matches his results against the expectations of the various theories of diversity. He discusses at length the other types of evidence as well.

Mr. Smith also deals with the clonal specialization of cells to produce a single antibody, and the relationship of this specialization to the somatic joining of antibody half-genes, which is one of the immune system's most important peculiarities.

Introductory material is provided to make this work understandable to molecular geneticists not versed in immunology and to immunologists not versed in molecular genetics.

This is a timely book offering a succinct and coherent summary of the various lines of evidence in a confused and controversial field.

Viruses are the most abundant biological entities on Earth, and arguably the most successful. They are not technically alive, but—as infectious vehicles of genetic information—they have a remarkable capacity to invade, replicate, and evolve within living cells. Synthesizing a large body of recent research, Michael Cordingley goes beyond our familiarity with viral infections to show how viruses spur evolutionary change in their hosts, shape global ecosystems, and influence every domain of life.

In the last few decades, research has revealed that viruses are fundamental to the photosynthetic capacity of the world’s oceans and the composition of the human microbiome. Perhaps most fascinating, viruses are now recognized as remarkable engines of the genetic innovation that fuels natural selection and catalyzes evolution in all domains of life. Viruses have coevolved with their hosts since the beginning of life on our planet and are part of the evolutionary legacy of every species that has ever lived.

Cordingley explains how viruses are responsible for the creation of many feared bacterial diseases and the emergence of newly pathogenic and drug-resistant strains. And as more and more viruses jump to humans from other animals, new epidemics of viral disease will threaten global society. But Cordingley shows that we can adapt, relying on our evolved cognitive and cultural capacities to limit the consequences of viral infections. Piecing together the story of viruses’ major role within and beyond human disease, Viruses creates a valuable roadmap through the rapidly expanding terrain of virology.

This insightful study examines the deeply personal and heart-wrenching tensions among financial considerations, emotional attachments, and moral arguments that motivate end-of-life decisions.

America’s health care system was built on the principle that life should be prolonged whenever possible, regardless of the costs. This commitment has often meant that patients spend their last days suffering from heroic interventions that extend their life by only weeks or months. Increasingly, this approach to end-of-life care is coming under scrutiny, from a moral as well as a financial perspective. Sociologist Roi Livne documents the rise and effectiveness of hospice and palliative care, and growing acceptance of the idea that a life consumed by suffering may not be worth living.

Values at the End of Life combines an in-depth historical analysis with an extensive study conducted in three hospitals, where Livne observed terminally ill patients, their families, and caregivers negotiating treatment. Livne describes the ambivalent, conflicted moments when people articulate and act on their moral intuitions about dying. Interviews with medical staff allowed him to isolate the strategies clinicians use to help families understand their options. As Livne discovered, clinicians are advancing the idea that invasive, expensive hospital procedures often compound a patient’s suffering. Affluent, educated families were more readily persuaded by this moral calculus than those of less means.

Once defiant of death—or even in denial—many American families and professionals in the health care system are beginning to embrace the notion that less treatment in the end may be better treatment.

From Michael Pollan to locavores, Whole Foods to farmers' markets,  today cooks and foodies alike are paying more attention than ever before to the history of the food they bring into their kitchens—and especially to vegetables. Whether it’s an heirloom tomato, curled cabbage, or succulent squash, from a farmers' market or a backyard plot, the humble vegetable offers more than just nutrition—it also represents a link with long tradition of farming and gardening, nurturing and breeding.

In this charming new book, those veggies finally get their due. In capsule biographies of eleven different vegetables—artichokes, beans, chard, cabbage, cardoons, carrots, chili peppers, Jerusalem artichokes, peas, pumpkins, and tomatoes—Evelyne Bloch-Dano explores the world of vegetables in all its facets, from science and agriculture to history, culture, and, of course, cooking. From the importance of peppers in early international trade to the most recent findings in genetics, from the cultural cachet of cabbage to Proust’s devotion to beef-and-carrot stew, to the surprising array of vegetables that preceded the pumpkin as the avatar of All Hallow’s Eve, Bloch-Dano takes readers on a dazzling tour of the fascinating stories behind our daily repasts.

Spicing her cornucopia with an eye for anecdote and a ready wit, Bloch-Dano has created a feast that’s sure to satisfy gardeners, chefs, and eaters alike.

Ai Hisano exposes how corporations, the American government, and consumers shaped the colors of what we eat and even the colors of what we consider “natural,” “fresh,” and “wholesome.”

The yellow of margarine, the red of meat, the bright orange of “natural” oranges—we live in the modern world of the senses created by business. Ai Hisano reveals how the food industry capitalized on color, and how the creation of a new visual vocabulary has shaped what we think of the food we eat. Constructing standards for the colors of food and the meanings we associate with them—wholesome, fresh, uniform—has been a business practice since the late nineteenth century, though one invisible to consumers. Under the growing influences of corporate profit and consumer expectations, firms have sought to control our sensory experiences ever since.

Visualizing Taste explores how our perceptions of what food should look like have changed over the course of more than a century. By examining the development of color-controlling technology, government regulation, and consumer expectations, Hisano demonstrates that scientists, farmers, food processors, dye manufacturers, government officials, and intermediate suppliers have created a version of “natural” that is, in fact, highly engineered. Retailers and marketers have used scientific data about color to stimulate and influence consumers’—and especially female consumers’—sensory desires, triggering our appetites and cravings. Grasping this pivotal transformation in how we see, and how we consume, is critical to understanding the business of food.

Vodka is the most versatile of spirits. While people in Eastern Europe and the Baltic often drink it neat, swallowing it in one gulp, others use it in cocktails and mixed drinks—bloody marys, screwdrivers, white russians, and Jell-O shots—or mix it with tonic water or ginger beer to create a refreshing drink. Vodka manufacturers even infuse it with flavors ranging from lemon and strawberry to chocolate, bubble gum, and bacon. Created by distilling fermented grains, potatoes, beets, or other vegetables, this colorless, tasteless, and odorless liquor has been enjoyed by both the rich and the poor throughout its existence, but it has also endured many obstacles along its way to global popularity.

As almost (or, truly, virtually) every aspect of making and viewing movies is replaced by digital technologies, even the notion of “watching a film” is fast becoming an anachronism. With the likely disappearance of celluloid film stock as a medium, and the emergence of new media competing for an audience, what will happen to cinema—and to cinema studies? In the first of two books exploring this question, D. N. Rodowick considers the fate of film and its role in the aesthetics and culture of moviemaking and viewing in the twenty-first century.

Here Rodowick proposes and examines three different critical responses to the disappearance of film in relation to other time-based media, and to the study of contemporary visual culture. Film, he suggests, occupies a special place in the genealogy of the arts of the virtual: while film disappears, cinema persists—at least in the narrative forms imagined by Hollywood since 1915. Rodowick also observes that most so-called “new media” are fashioned upon a cinematic metaphor. His book helps us see how digital technologies are serving, like television and video before them, to perpetuate the cinematic as the mature audiovisual culture of the twentieth century—and, at the same time, how they are preparing the emergence of a new audiovisual culture whose broad outlines we are only just beginning to distinguish.

Today, war is considered a last resort for resolving disagreements. But a day of staged slaughter on the battlefield was once seen as a legitimate means of settling political disputes. James Whitman argues that pitched battle was essentially a trial with a lawful verdict. And when this contained form of battle ceased to exist, the law of victory gave way to the rule of unbridled force. The Verdict of Battle explains why the ritualized violence of the past was more effective than modern warfare in bringing carnage to an end, and why humanitarian laws that cling to a notion of war as evil have led to longer, more barbaric conflicts.

Belief that sovereigns could, by rights, wage war for profit made the eighteenth century battle’s golden age. A pitched battle was understood as a kind of legal proceeding in which both sides agreed to be bound by the result. To the victor went the spoils, including the fate of kingdoms. But with the nineteenth-century decline of monarchical legitimacy and the rise of republican sentiment, the public no longer accepted the verdict of pitched battles. Ideology rather than politics became war’s just cause. And because modern humanitarian law provided no means for declaring a victor or dispensing spoils at the end of battle, the violence of war dragged on.

The most dangerous wars, Whitman asserts in this iconoclastic tour de force, are the lawless wars we wage today to remake the world in the name of higher moral imperatives.