This volume brings together two previously unpublished works by the late George Scatchard. One of the most eminent physical chemists of this century, Scatchard, in collaboration with Edwin Cohn, had enormous influence on the development of protein chemistry. The “Scatchard Plot,” a device for evaluating the interaction of proteins with smaller molecules, is today a ubiquitous feature of articles on biochemistry, immunology, and endocrinology.

These two monographs concern the laws of thermodynamics and the Oebye-Huckel theory as they are applied to the physical chemistry of inorganic and organic systems in solution. A unique feature of both works is their detailed extension of thermodynamic principles to the interactions of dissolved proteins with each other and with small molecules. They represent one of the most important links between the classical physical chemistry of the first four decades of this century and the contemporary science of protein chemistry.

Known previously only to a limited audience of Scatchard's students and colleagues, these remarkable treatises deserve much wider circulation today. Succinct, comprehensive, and systematic, they will stand as useful guides to one of the central sciences of our time.

Life would not exist without sensitive, or soft, matter. All biological structures depend on it, including red blood globules, lung fluid, and membranes. So do industrial emulsions, gels, plastics, liquid crystals, and granular materials. What makes sensitive matter so fascinating is its inherent versatility. Shape-shifting at the slightest provocation, whether a change in composition or environment, it leads a fugitive existence.

Physicist Michel Mitov brings drama to molecular gastronomy (as when two irreconcilable materials are mixed to achieve the miracle of mayonnaise) and offers answers to everyday questions, such as how does paint dry on canvas, why does shampoo foam better when you “repeat,” and what allows for the controlled release of drugs? Along the way we meet a futurist cook, a scientist with a runaway imagination, and a penniless inventor named Goodyear who added sulfur to latex, quite possibly by accident, and created durable rubber.

As Mitov demonstrates, even religious ritual is a lesson in the surprising science of sensitive matter. Thrice yearly, the reliquary of St. Januarius is carried down cobblestone streets from the Cathedral to the Church of St. Clare in Naples. If all goes as hoped—and since 1389 it often has—the dried blood contained in the reliquary’s largest vial liquefies on reaching its destination, and Neapolitans are given a reaffirming symbol of renewal.