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Explainable Artificial Intelligence in Medical Decision Support Systems
Agbotiname Lucky Imoize
The Institution of Engineering and Technology, 2022
Medical decision support systems (MDSS) are computer-based programs that analyse data within a patient's healthcare records to provide questions, prompts, or reminders to assist clinicians at the point of care. Inputting a patient's data, symptoms, or current treatment regimens into an MDSS, clinicians are assisted with the identification or elimination of the most likely potential medical causes, which can enable faster discovery of a set of appropriate diagnoses or treatment plans. Explainable AI (XAI) is a "white box" model of artificial intelligence in which the results of the solution can be understood by the users, who can see an estimate of the weighted importance of each feature on the model's predictions, and understand how the different features interact to arrive at a specific decision.
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Explaining Science
A Cognitive Approach
Ronald N. Giere
University of Chicago Press, 1988
"This volume presents an attempt to construct a unified cognitive theory of science in relatively short compass. It confronts the strong program in sociology of science and the positions of various postpositivist philosophers of science, developing significant alternatives to each in a reeadily comprehensible sytle. It draws loosely on recent developments in cognitive science, without burdening the argument with detailed results from that source. . . . The book is thus a provocative one. Perhaps that is a measure of its value: it will lead scholars and serious student from a number of science studies disciplines into continued and sharpened debate over fundamental questions."—Richard Burian, Isis

"The writing is delightfully clear and accessible. On balance, few books advance our subject as well."—Paul Teller, Philosophy of Science
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Explorations in Developmental Biology
Chandler Fulton and Attila Klein
Harvard University Press, 1976

Explorations in Developmental Biology is a revolutionary departure from time-honored introductory texts. The book is based on the premise that the substance, concepts, and excitement of contemporary developmental biology are best communicated to students by using the same form in which they were first communicated to the scientific community — original research reports. But a simple collection of original papers is not sufficient; it is too limited in scope and too disjointed, and students are not prepared to read them with understanding. In this book, designed to serve as the principal text for a first or second course in developmental biology, basic concepts are presented in a series of 22 chapters that focus on major, often unsolved, problems ranging from self-assembly to embryonic induction to cellular communication by surface contact. Within each chapter the authors provide the necessary background in developmental biology, and also describe the specific experimental procedures that enable the student to understand and appreciate the contributions of significant research papers that are included. The authors' texts and the reprinted papers are integrated into a cohesive whole, so that each chapter provides up-to-date information about an important area of developmental biology and raises specific questions.

Throughout, the text is profusely illustrated with original drawings and with figures taken from the literature, and each chapter contains a brief guide to pertinent publications.

Explorations in Developmental Biology makes it possible for teachers and students to penetrate the perennial barrier between classroom and research laboratory. Students who use this book are well equipped to move on to more advanced studies in biology; for they will have acquired the ability to use and to evaluate original scientific communications and will have assimilated the subject matter of a science that is at the center of modern biology.

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Explorations in the Icy North
How Travel Narratives Shaped Arctic Science in the Nineteenth Century
Nanna Katrine Lüders Kaalund
University of Pittsburgh Press, 2021

Science in the Arctic changed dramatically over the course of the nineteenth century, when early, scattered attempts in the region to gather knowledge about all aspects of the natural world transitioned to a more unified Arctic science under the First International Polar Year in 1882. The IPY brought together researchers from multiple countries with the aim of undertaking systematic and coordinated experiments and observations in the Arctic and Antarctic. Harsh conditions, intense isolation, and acute danger inevitably impacted the making and communicating of scientific knowledge. At the same time, changes in ideas about what it meant to be an authoritative observer of natural phenomena were linked to tensions in imperial ambitions, national identities, and international collaborations of the IPY. Through a focused study of travel narratives in the British, Danish, Canadian, and American contexts, Nanna Katrine Lüders Kaalund uncovers not only the transnational nature of Arctic exploration, but also how the publication and reception of literature about it shaped an extreme environment, its explorers, and their scientific practices. She reveals how, far beyond the metropole—in the vast area we understand today as the North American and Greenlandic Arctic—explorations and the narratives that followed ultimately influenced the production of field science in the nineteenth century.

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Explorations in the Life of Fishes
N. B. Marshall
Harvard University Press, 1971

Exploring what he considers to be the outstanding aspects of fish biology, Mr. Marshall surveys the present knowledge in the field and suggests possibilities for future investigation.

He considers the causes of the overwhelming predominance of the teleost fishes, discusses the biology of deep-sea fishes, and studies such aspects of dynamic design as body form, fin pattern, muscular organization, and certain neural features in relation to movement and water.

His last chapter, on convergent evolution, deals with convergences among fishes as well as with convergences among fishes and invertebrates, particularly crustaceans and cephalopods.

The volume is illustrated with a chart on evolutionary relationships of fishes and over fifty line drawings.

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Exploratory Experiments
Ampère, Faraday, and the Origins of Electrodynamics
Friedrich Steinle
University of Pittsburgh Press, 2016
The nineteenth century was a formative period for electromagnetism and electrodynamics. Hans Christian Ørsted’s groundbreaking discovery of the interaction between electricity and magnetism in 1820 inspired a wave of research, led to the science of electrodynamics, and resulted in the development of electromagnetic theory. Remarkably, in response, André-Marie Ampère and Michael Faraday developed two incompatible, competing theories. Although their approaches and conceptual frameworks were fundamentally different, together their work launched a technological revolution—laying the foundation for our modern scientific understanding of electricity—and one of the most important debates in physics, between electrodynamic action-at-a-distance and field theories.

In this foundational study, Friedrich Steinle compares the influential work of Ampère and Faraday to reveal the prominent role of exploratory experimentation in the development of science. While this exploratory phase was responsible for decisive conceptual innovations, it has yet to be examined in such great detail. Focusing on Ampère’s and Faraday’s research practices, reconstructed from previously unknown archival materials, including laboratory notes, diaries, letters, and interactions with instrument makers, this book considers both the historic and epistemological basis of exploratory experimentation and its importance to scientific development.

Winner of the 2017 Ungar German Translations Award from the American Translators Association
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Exploring Apocalyptica
Coming to Terms with Environmental Alarmism
Frank Uekötter
University of Pittsburgh Press, 2018
Environmental alarmism has long been a political bellwether. Tell me what you think about the green apocalypse, and I'll tell you where you stand on the issues. But as the environmental heydays of the 1970s move into perspective, the time has come for a reassessment. Horror scenarios create a legacy whose effects have largely escaped attention. Based on case studies from four continents and the North Atlantic, ExploringApocalyptica argues for a reevaluation of familiar clichés. It shows that environmentalists were less apocalyptic than commonly thought, and other groups were far more enthusiastic. It traces an interconnection with Cold War fears and economic depressions and demonstrates how alarmism faced limits in the Global South. It also suggests that past horror scenarios impose constraints on ongoing debates. At a time when climate change turns from a scenario into an experienced reality, this book charts paths for an age that may have already moved beyond the peak apocalypse.
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Exploring Mars
Chronicles from a Decade of Discovery
Scott Hubbard; Foreword by Bill Nye
University of Arizona Press, 2012

The Red Planet has been a subject of fascination for humanity for thousands of years, becoming part of our folklore and popular culture. The most Earthlike of the planets in our solar system, Mars may have harbored some form of life in the past and may still possess an ecosystem in some underground refuge. The mysteries of this fourth planet from our Sun make it of central importance to NASA and its science goals for the twenty-first century.  

In the wake of the very public failures of the Mars Polar Lander and the Mars Climate Orbiter in 1999, NASA embarked on a complete reassessment of the Mars Program. Scott Hubbard was asked to lead this restructuring in 2000, becoming known as the "Mars Czar." His team's efforts resulted in a very successful decade-long series of missions—each building on the accomplishments of those before it—that adhered to the science adage "follow the water" when debating how to proceed. Hubbard's work created the Mars Odyssey mission, the twin rovers Spirit and Opportunity, the Mars Reconnaissance Orbiter, the Phoenix mission, and most recently the planned launch of the Mars Science Laboratory

Now for the first time Scott Hubbard tells the complete story of how he fashioned this program, describing both the technical and political forces involved and bringing to life the national and international cast of characters engaged in this monumental endeavor.  Blending the exciting stories of the missions with the thrills of scientific discovery, Exploring Mars will intrigue anyone interested in the science, the engineering, or the policy of investigating other worlds.
 


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Exploring the Scientific Method
Cases and Questions
Edited by Steven Gimbel
University of Chicago Press, 2011

From their grade school classrooms forward, students of science are encouraged to memorize and adhere to the “scientific method”—a model of inquiry consisting of five to seven neatly laid-out steps, often in the form of a flowchart. But walk into the office of a theoretical physicist or the laboratory of a biochemist and ask “Which step are you on?” and you will likely receive a blank stare. This is not how science works. But science does work, and here award-winning teacher and scholar Steven Gimbel provides students the tools to answer for themselves this question: What actually is the scientific method?

           
Exploring the Scientific Method pairs classic and contemporary readings in the philosophy of science with milestones in scientific discovery to illustrate the foundational issues underlying scientific methodology. Students are asked to select one of nine possible fields—astronomy, physics, chemistry, genetics, evolutionary biology, psychology, sociology, economics, or geology—and through carefully crafted case studies trace its historical progression, all while evaluating whether scientific practice in each case reflects the methodological claims of the philosophers. This approach allows students to see the philosophy of science in action and to determine for themselves what scientists do and how they ought to do it.

            
Exploring the Scientific Method will be a welcome resource to introductory science courses and all courses in the history and philosophy of science.        

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Exploring 'Unseen' Social Capital in Community Participation
Everyday Lives of Poor Mainland Chinese Migrants in Hong Kong
Sam Wong
Amsterdam University Press, 2008
This volume argues that using social capital to eradicate poverty is unlikely to succeed because its mainstream approach mistakenly assumes that social capital necessarily benefits poor people. The inadequacy of that assumption, Sam Wong argues, calls for a reassessment of human motivations, institutional dynamics, and the complexity of structures in social capital building. Proposing a “pro-poor” perspective, in which poverty-specific outcomes are highlighted, he suggests an exploration of “unseen” social capital is in order—not only to challenge the mainstream understanding of “seen” social capital, but to demonstrate the need for everyday cooperation, which is shaped by social norms, influenced by conscious and unconscious motivations, and subject to changes in priority based on livelihood. A useful volume for both policy makers and practitioners, Exploring ‘Unseen’ Social Capital in Community Participation offers a fresh perspective in thinking about civic and social agency.
 
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Exposed
Environmental Politics and Pleasures in Posthuman Times
Stacy Alaimo
University of Minnesota Press, 2016

Opening with the statement “The anthropocene is no time to set things straight,” Stacy Alaimo puts forth potent arguments for a material feminist posthumanism in the chapters that follow.

From trans-species art and queer animals to naked protesting and scientific accounts of fishy humans, Exposed argues for feminist posthumanism immersed in strange agencies and scale-shifting ethics. Including such divergent topics as landscape art, ocean ecologies, and plastic activism, Alaimo explores our environmental predicaments to better understand feminist occupations of transcorporeal subjectivity.

She puts scientists, activists, artists, writers, and theorists in conversation, revealing that the state of the planet in the twenty-first century has radically transformed ethics, politics, and what it means to be human. Ultimately, Exposed calls for an environmental stance in which, rather than operating from an externalized perspective, we think, feel, and act as the very stuff of the world.

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The Expression of the Emotions in Man and Animals
Charles Darwin
University of Chicago Press, 1965
Darwin's work of 1872 still provides the point of departure for research in the theory of emotion and expression. Although he lacked the modern research tool of cybernetics, his basic methods have not been improved upon: the study of infants, of the insane, of paintings and sculpture, of some of the commoner animals; the use of photographs of expression submitted to different judges; and the comparative study of expression among different peoples. This new edition will be warmly welcomed by those behavioral scientists who have recently shown an intense interest in the scientific study of expression. Lay readers, too, will be struck by the freshness and directness of this book, which includes, among other data, Darwin's delightfully objective analysis of his own baby's smiles and pouts.
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The Extended Organism
The Physiology of Animal-Built Structures
J. Scott Turner
Harvard University Press, 2000
Can the structures that animals build--from the humble burrows of earthworms to towering termite mounds to the Great Barrier Reef--be said to live? However counterintuitive the idea might first seem, physiological ecologist Scott Turner demonstrates in this book that many animals construct and use structures to harness and control the flow of energy from their environment to their own advantage. Building on Richard Dawkins's classic, The Extended Phenotype, Turner shows why drawing the boundary of an organism's physiology at the skin of the animal is arbitrary. Since the structures animals build undoubtedly do physiological work, capturing and channeling chemical and physical energy, Turner argues that such structures are more properly regarded not as frozen behaviors but as external organs of physiology and even extensions of the animal's phenotype. By challenging dearly held assumptions, a fascinating new view of the living world is opened to us, with implications for our understanding of physiology, the environment, and the remarkable structures animals build.
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Extinct Madagascar
Picturing the Island's Past
Steven M. Goodman and William L. Jungers
University of Chicago Press, 2014
The landscapes of Madagascar have long delighted zoologists, who have discovered, in and among the island’s baobab trees and thickets, a dizzying array of animals, including something approaching one hundred species of lemur. Madagascar’s mammal fauna, for example, is far more diverse, and more endemic, than early explorers and naturalists ever dreamed of. But in the past 2,500 or so years—a period associated with natural climatic shifts and ecological change, as well as partially coinciding with the arrival of the island’s first human settlers—a considerable proportion of Madagascar’s forests have disappeared; and in the wake of this loss, a number of species unique to Madagascar have vanished forever into extinction.

In Extinct Madagascar, noted scientists Steven M. Goodman and William L. Jungers explore the recent past of these land animal extinctions. Beginning with an introduction to the geologic and ecological history of Madagascar that provides context for the evolution, diversification, and, in some cases, rapid decline of the Malagasy fauna, Goodman and Jungers then seek to recapture these extinct mammals in their environs. Aided in their quest by artist Velizar Simeonovski’s beautiful and haunting digital paintings—images of both individual species and ecosystem assemblages reproduced here in full color—Goodman and Jungers reconstruct the lives of these lost animals and trace their relationships to those still living.

Published in conjunction with an exhibition of Simeonovski’s artwork set to open at the Field Museum, Chicago, in the fall of 2014, Goodman and Jungers’s awe-inspiring book will serve not only as a sobering reminder of the very real threat of extinction, but also as a stunning tribute to Madagascar’s biodiversity and a catalyst for further research and conservation.
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Extinction and Biogeography of Tropical Pacific Birds
David W. Steadman
University of Chicago Press, 2006
Sprinkled across the tropical Pacific, the innumerable islands of Oceania are home to some of the most unique bird communities on the planet, and they sustain species found nowhere else on earth. Many of the birds that live in this region are endangered, however; many more have become extinct as a result of human activity, in both recent and prehistoric times.

Reconstructing the avian world in the same way archeologists re-create ancient human societies, David Steadman—a leading authority on tropical Pacific avian paleontology—has spent the past two decades in the field, digging through layers of soil in search of the bones that serve as clues to the ancient past of island bird communities. His years of indefatigable research and analysis are the foundation for Extinction and Biogeography of Tropical Pacific Birds, a monumental study of the landbirds of tropical Pacific islands—especially those from Fiji eastward to Easter Island—and an intricate history of the patterns and processes of island biology over time. 

Using information gleaned from prehistoric specimens, Steadman reconstructs the birdlife of tropical Pacific islands as it existed before the arrival of humans and in so doing corrects the assumption that small, remote islands were unable to support rich assemblages of plants and animals. Easter Island, for example, though devoid of wildlife today, was the world’s richest seabird habitat before Polynesians arrived more than a millennium ago. The forests of less isolated islands in the Pacific likewise teemed with megapodes, rails, pigeons, parrots, kingfishers, and songbirds at first human contact. 

By synthesizing data from the distant past, Steadman hopes to inform present conservation programs. Grounded in geology, paleontology, and archeology, but biological at its core, Extinction and Biogeography of Tropical Pacific Birds is an exceptional work of unparalleled scholarship that will stimulate creative discussions of terrestrial life on oceanic islands for years to come.
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Extinctions
From Dinosaurs to You
Charles Frankel
University of Chicago Press, 2024
A compelling answer to an important question: Can past mass extinctions teach us how to avoid future planetary disaster?

On its face, the story of mass extinction on Earth is one of unavoidable disaster. Asteroid smashes into planet; goodbye dinosaurs. Planetwide crises seem to be beyond our ability to affect or evade. Extinctions argues that geological history tells an instructive story, one that offers important signs for us to consider. When the asteroid struck, Charles Frankel explains, it set off a wave of cataclysms that wore away at the global ecosystem until it all fell apart. What if there had been a way to slow or even turn back these tides? Frankel believes that the answer to this question holds the key to human survival.

Human history, from the massacre of Ice Age megafauna to today’s industrial climate change, has brought the planet through another series of cataclysmic events. But the history of mass extinction together with the latest climate research, Frankel maintains, shows us a way out. If we curb our destructive habits, particularly our drive to kill and consume other species, and work instead to conserve what biodiversity remains, the Earth might yet recover. Rather than await decisive disaster, Frankel argues that we must instead take action to reimagine what it means to be human. As he eloquently explains, geological history reminds us that life is not eternal; we can disappear, or we can become something new and continue our evolutionary adventure.
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Extraordinary Orchids
Sandra Knapp
University of Chicago Press, 2021
Perching on tropical trees, partnering with fungi to reproduce, or deceiving birds and amorous insects to promote pollination, orchids fascinate. In the exquisitely illustrated Extraordinary Orchids, award-winning botanist and writer Sandra Knapp tells the stories behind some of the bizarre lifestyles and interactions that scientists have uncovered among many species of the orchid family.

Orchids deserve such a visual celebration: parts of the orchid flower have shapes unlike any other flowering plant, and the sheer number of species means they have a seemingly endless ability to create ever more fantastical forms. In fact, many orchid common names refer to the shape-shifting forms of their flowers—the “man-orchids” or “monkey-orchids” are so called because of their resemblance to the primate form. Orchids lend themselves to depiction, and botanical artworks of them abound. Who could resist painting or drawing such odd shapes?

Illustrated with stunning artwork, much from the archives of the Natural History Museum in London and never before published, Extraordinary Orchids includes depictions from celebrated botanical artists such as Ferdinand and Franz Bauer, Arthur Harry Church, and Sydney Parkinson, revealing the weird and wonderful lives of this most diverse of plant families.
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Extreme Conservation
Life at the Edges of the World
Joel Berger
University of Chicago Press, 2018
"Extraordinary. . . . Berger is a hero of biology who deserves the highest honors that science can bestow."—Tim Flannery, New York Review of Books

On the Tibetan Plateau, there are wild yaks with blood cells thinner than those of horses’ by half, enabling the endangered yaks to survive at 40 below zero and in the lowest oxygen levels of the mountaintops. But climate change is causing the snow patterns here to shift, and with the snows, the entire ecosystem. Food and water are vaporizing in this warming environment, and these beasts of ice and thin air are extraordinarily ill-equipped for the change. A journey into some of the most forbidding landscapes on earth, Joel Berger’s Extreme Conservation is an eye-opening, steely look at what it takes for animals like these to live at the edges of existence. But more than this, it is a revealing exploration of how climate change and people are affecting even the most far-flung niches of our planet.

Berger’s quest to understand these creatures’ struggles takes him to some of the most remote corners and peaks of the globe: across Arctic tundra and the frozen Chukchi Sea to study muskoxen, into the Bhutanese Himalayas to follow the rarely sighted takin, and through the Gobi Desert to track the proboscis-swinging saiga. Known as much for his rigorous, scientific methods of developing solutions to conservation challenges as for his penchant for donning moose and polar bear costumes to understand the mindsets of his subjects more closely, Berger is a guide par excellence. He is a scientist and storyteller who has made his life working with desert nomads, in zones that typically require Sherpas and oxygen canisters. Recounting animals as charismatic as their landscapes are extreme, Berger’s unforgettable tale carries us with humor and expertise to the ends of the earth and back. But as his adventures show, the more adapted a species has become to its particular ecological niche, the more devastating climate change can be. Life at the extremes is more challenging than ever, and the need for action, for solutions, has never been greater.
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Extreme Measures
The Ecological Energetics of Birds and Mammals
Brian K. McNab
University of Chicago Press, 2012

Along with reproduction, balancing energy expenditure with the limits of resource acquisition is essential for both a species and a population to survive. But energy is a limited resource, as we know well, so birds and mammals—the most energy-intensive fauna on the planet—must reduce energy expenditures to maintain this balance, some taking small steps, and others extreme measures.

Here Brian K. McNab draws on his over sixty years in the field to provide a comprehensive account of the energetics of birds and mammals, one fully integrated with their natural history. McNab begins with an overview of thermal rates—much of our own energy is spent maintaining our 98.6?F temperature—and explains how the basal rate of metabolism drives energy use, especially in extreme environments. He then explores those variables that interact with the basal rate of metabolism, like body size and scale and environments, highlighting their influence on behavior, distribution, and even reproductive output. Successive chapters take up energy and population dynamics and evolution. A critical central theme that runs through the book is how the energetic needs of birds and mammals come up against rapid environmental change and how this is hastening the pace of extinction.

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The Eye of the Lynx
Galileo, His Friends, and the Beginnings of Modern Natural History
David Freedberg
University of Chicago Press, 2002
Some years ago, David Freedberg opened a dusty cupboard at Windsor Castle and discovered hundreds of vividly colored, masterfully precise drawings of all sorts of plants and animals from the Old and New Worlds. Coming upon thousands more drawings like them across Europe, Freedberg finally traced them all back to a little-known scientific organization from seventeenth-century Italy called the Academy of Linceans (or Lynxes).

Founded by Prince Federico Cesi in 1603, the Linceans took as their task nothing less than the documentation and classification of all of nature in pictorial form. In this first book-length study of the Linceans to appear in English, Freedberg focuses especially on their unprecedented use of drawings based on microscopic observation and other new techniques of visualization. Where previous thinkers had classified objects based mainly on similarities of external appearance, the Linceans instead turned increasingly to sectioning, dissection, and observation of internal structures. They applied their new research techniques to an incredible variety of subjects, from the objects in the heavens studied by their most famous (and infamous) member Galileo Galilei—whom they supported at the most critical moments of his career—to the flora and fauna of Mexico, bees, fossils, and the reproduction of plants and fungi. But by demonstrating the inadequacy of surface structures for ordering the world, the Linceans unwittingly planted the seeds for the demise of their own favorite method—visual description-as a mode of scientific classification.

Profusely illustrated and engagingly written, Eye of the Lynx uncovers a crucial episode in the development of visual representation and natural history. And perhaps as important, it offers readers a dazzling array of early modern drawings, from magnificently depicted birds and flowers to frogs in amber, monstrously misshapen citrus fruits, and more.
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Eyewitness to Science
Scientists and Writers Illuminate Natural Phenomena from Fossils to Fractals
John Carey
Harvard University Press
Plotting the development of modern science from Leonardo da Vinci to Chaos Theory, John Carey chooses accounts by scientists themselves that are both elegant and arrestingly written. The classic science-writers are here: Darwin, Huxley, Fabre. So, too, are the luminaries of the late-twentieth-century genre of popular science-writing which, Carey argues, challenges contemporary poetry and fiction in its imaginative power.
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