Eduard Hoffman is a microbiologist with an interest in relationships. He believes he's found "a strain of separation virus" raging in West Berlin in 1983, which terminates every relationship within three years, 167 days, and 2 hours. As Eduard attempts to evade the virus, he tangles with Germany's Nazi guilt, memories of his father, a wayward mouse, and other threats to his identity in a divided country.

"A little Don Giovanni, a little café sociology, a little laboratory science, a little Berlin wit—it's a pleasant mix."—Suzanne Ruta, New York Times Book Review

"With its poignant valedictory to its protagonists' waning youth and its rueful placing of them in the firing line of history, Couplings achieves a balance of light and dark that is utterly persuasive."—Michael Upchurch, San Francisco Chronicle Book Review