"1 Introduction
1.1 Preamble
1.2 Nanofibres
1.3 Key concepts in drug delivery
1.4 Nanofibre characterisation
1.5 An overview of contemporary pharmaceutical technology
1.6 Summary
1.7 References
1.8 Bibliography
2 Electrospinning fundamentals
2.1 Background
2.2 A brief history of electrospinning
2.3 EHD fundamentals
2.4 Understanding the electrospinning process
2.5 The parameters affecting electrospinning
2.6 The experimental set- up
2.7 Fibre properties
2.8 Characterisation
2.9 Summary
2.10 References
3 Monoaxial electrospinning
3.1 Introduction
3.2 Experimental considerations
3.3 Fibre properties
3.4 Some typical results
3.5 Fast- dissolving drug delivery systems
3.6 Extended- release systems
3.7 pH- controlled delivery
3.8 Pulsatile release
3.9 Multilayer materials
3.10 Thermoresponsive systems
3.11 Emulsion and suspension electrospinning
3.12 Tissue- engineering applications
3.13 Using fibres as sacrificial templates
3.14 Conclusions
3.15 References
4 Coaxial and multi- axial electrospinning
4.1 Introduction
4.2 Experimental considerations
4.3 Extended- release systems
4.4 Targeted drug delivery
4.5 Multifunctional materials
4.6 Other applications
4.7 Protein delivery systems
4.8 Cell electrospinning
4.9 Modified coaxial spinning
4.10 Triaxial and quad- axial systems
4.11 Conclusions
4.12 References
5 Side- by- side electrospinning
5.1 Introduction
5.2 Experimental considerations
5.3 Janus fibres in drug delivery
5.4 Conclusions
5.5 References
6 Alternative nanofibre fabrication approaches
6.1 Introduction
6.2 Alternating current (AC) electrospinning
6.3 Melt electrospinning
6.4 Centrifugal spinning
6.5 Solution blowing and melt blowing
6.6 Electroblowing
6.7 Pressurised gyration
6.8 Electrospraying
6.9 Microfluidic spinning
6.10 Fibre production on the move
6.11 Other techniques
6.12 Conclusions
6.13 References
7 Moving from the bench to the clinic
7.1 Introduction
7.2 Scale- up
7.3 Regulatory requirements and GMP manufacturing
7.4 Conclusions
7.5 References
8 Conclusions and outlook "