Anna Morandi Manzolini (1714-74), a woman artist and scientist, surmounted meager origins and limited formal education to become one of the most acclaimed anatomical sculptors of the Enlightenment. The Lady Anatomist tells the story of her arresting life and times, in light of the intertwined histories of science, gender, and art that complicated her rise to fame in the eighteenth century.
Examining the details of Morandi’s remarkable life, Rebecca Messbarger traces her intellectual trajectory from provincial artist to internationally renowned anatomical wax modeler for the University of Bologna’s famous medical school. Placing Morandi’s work within its cultural and historical context, as well as in line with the Italian tradition of anatomical studies and design, Messbarger uncovers the messages contained within Morandi’s wax inscriptions, part complex theories of the body and part poetry. Widely appealing to those with an interest in the tangled histories of art and the body, and including lavish, full-color reproductions of Morandi’s work, The Lady Anatomist is a sophisticated biography of a true visionary.
The stormy life of one of the most colorful and complex characters in early 19th-century medicine
Human Structure is an innovative introduction to human gross anatomy with a twofold approach to view the basics of anatomy from a broad scientific perspective and to explain the facts of form and function in terms and concepts that minimize the usual confusion and anxiety of beginning anatomy studies. Functional, comparative, and developmental anatomy are ingeniously woven into a single explanatory perspective, presenting human anatomy as an intelligible whole rather than as a heap of disconnected facts to be memorized. As a result, Human Structure is suitable not only for first-year medical students but also for undergraduates in premedical or biological science courses, for students in paramedical or college-level nursing programs, and indeed for anyone seeking a refresher course in human anatomy.
The book begins with the generalized segmental organization characteristic of vertebrates and then examines the most obviously segmented parts of the human body: the bones, muscles, vessels, and nerves of the trunk between the neck and the pelvis. The book progresses through regions where the simple organizational plan has undergone more and more radical modifications and ends with the ancient and extreme specializations found in the head. At each step, the authors widen our intellectual understanding of how these modifications have been imposed, onto-genetically or phylogenetically, upon simpler precursors.
The prose is personal and literate, peppered with inventive elucidations of concepts and accompanied by a wealth of illustrations designed for conceptual clarity and ease of visualization. The level of presentation has been finely tuned, over several years of class testing, to enhance its pedagogical effectiveness in human anatomy courses.
Rapidly developing diagnostic and therapeutic methods involving direct contact with the human fetus—fetoscopy, fetal surgery, ultrasonic scanning— demand a precise knowledge of normal structural development during gestation. Toward achieving that goal of precision, Drs. Robert Shapiro and Franklin Robinson have created an atlas described by Richard L. Sidman as “a solid piece of research, executed with considerable esthetic as well as scholarly finesse, and [which] will serve as the definitive study on an important aspect of human fetal development.”
The authors have documented the early development of the human skull in terms of gross size, shape, and the behavior of the individual bones com posing the skull with reference to their ossification centers, ossification rates, and relationships. The data are presented in very high quality photographs and radiographs of the dried skull in several relevant orientations, low magnification color photomicrographs of well sectioned and stained specimens, and color photographs of an unusually fine series of transilluminated skulls prepared by the Spalteholz method. Line drawings are also presented to assist in interpretation.
The atlas is organized according to gestational age, and a tabular summary is given of the 63 specimens ranging in age from ten to forty fetal weeks.
This will be the basic normative standard reference for studies on develop mental skeletal disorders of the head and neck; it will be useful as well in the study of developmental brain diseases. Radiologists engaged in visualizing the fetus and diagnosing fetal diseases in situ by ultrasound, computerized tomography, and other methods will find this an invaluable tool.
"It is my hope," writes the author in his preface, "that the material collected in this monograph will provide a new perspective in some areas for those students, biologists, and physicians interested in the kidney but too involved with their special trees to notice some of the changes occurring in the forest in which they toil."
In the first up-to-date compendium to correlate the changes in kidney structure and function from the onset of organogenesis to the end of childhood growth, Dr. Wallace McCrory presents a new aspect of developmental pediatrics, skillfully explains the clinical enigmas surrounding the immature kidney, and suggests possible research areas for productive exploration. Clearly documented with tables and illustrations, the study synthesizes relevant new knowledge from the fields of embryology, biochemistry, and renal and growth physiology as a means of stimulating reappraisals of the current concepts of the pathophysiology of many childhood renal diseases. Included are reproductions of reconstructed micro dissections of the early stages in the developing human kidney taken from Dr. Jean Oliver's monograph Nephrons and Kidneys.
In his latest book, David Bainbridge combines an otherworldly journey through the central nervous system with an accessible and entertaining account of how the brain's anatomy has often misled anatomists about its function. Bainbridge uses the structure of the brain to set his book apart from the many volumes that focus on brain function. He shows that for hundreds of years, natural philosophers have been interested in the gray matter inside our skulls, but all they had to go on was its structure. Almost every knob, protrusion, canal, and crease was named before anyone had an inkling of what it did--a kind of biological terra incognita with many weird and wonderful names: the zonules of Zinn, the obex ("the most Scrabble-friendly word in all of neuroanatomy"), the aqueduct of Sylvius, the tract of Goll.
This uniquely accessible approach lays out what is known about the brain (its structure), what we can hope to know (its function), and what we may never know (its evolution). Along the way Bainbridge tells lots of wonderful stories about the "two pounds of blancmange" within our skulls, and tells them all with wit and style.
Cross-sectional Atlas of the Brain provides for the first time a set of high-resolution color cross-sections of the human brain (six times higher than that of the only complete data set available to date), each image accompanied by state-of-the-art MRI and CT scans of the same specimen. The sections were made at an interval of 147 micrometers of frozen tissue, virtually artifact free, with the blood vessels filled at sub-millimeter level. The more than two hundred detailed and fully annotated images in this atlas provide a complete body of reference to the gross anatomy of the brain. The accompanying line drawings of these images provide a roadmap for easy orientation.
The unparalleled resolution of the images also made it possible to derive cross-sections of the same specimen in all standard orientations--sagittal, coronal, and axial--through multi-planar computer-aided reformatting. This feature, which eliminates inter-subject variability, has never before been available in an anatomical atlas and makes the atlas especially useful for identifying and following anatomical structures in each plane. About the Companion DVD(View a sample in PDF format)
While the book itself contains 93 images (44 axial, 28 coronal, and 21 sagittal), the DVD contains the complete series of 1,481 axial images from one anatomic specimen from which the 44 axial images in the book were selected. These images were made at a resolution of 1525x1146 or 147 µm/pixel with a digital camera. The axial images are accompanied by 1,528 sagittal and 1,146 coronal images that were made by reformatting and reslicing the axial images. By placing these images side-by-side-by-side the DVD allows the user to see a particular region of the brain in all three orientations-axial, sagittal and coronal-simultaneously. These images are further accompanied by radiologic data. The DVD also allows the user to view a synchronized slide show of the images in all three planes. Images on the DVD that also appear in the book are highlighted with a blue background.
Cross-sectional Atlas of the Brain will be an essential reference for neuroscientists and clinicians (neurologists, radiologists, and neurosurgeons).
Once upon a time, neuroscience was born. A dazzling array of neurotechnologies emerged that, according to popular belief, have finally begun to unlock the secrets of the brain. But as the brain sciences now extend into all corners of cultural, social, political, and economic life, a yet newer world has taken shape: “neuroculture,” which goes further than ever before to tackle the profound ethical implications we face in consequence.
The Assemblage Brain unveils a major new concept of sense making, one that challenges conventional scientific and philosophical understandings of the brain. Drawing on Deleuze and Guattari, Tony D. Sampson calls for a radical critical theory that operates in the interferences between philosophy, science, art, and politics. From this novel perspective the book is structured around two questions: “What can be done to a brain?” and “What can a brain do?” Sampson examines the rise of neuroeconomics in informing significant developments in computer work, marketing, and the neuropharmaceutical control of inattentiveness in the classroom. Moving beyond the neurocapitalist framework, he then reestablishes a place for proto-subjectivity in which biological and cultural distinctions are reintegrated in an understanding of the brain as an assemblage.
The Assemblage Brain unravels the conventional image of thought that underpins many scientific and philosophical accounts of how sense is produced, providing a new view of our current time in which capitalism and the neurosciences endeavor to colonize the brain.
In one sense, human heads function much like those of other mammals. We use them to chew, smell, swallow, think, hear, and so on. But, in other respects, the human head is quite unusual. Unlike other animals, even our great ape cousins, our heads are short and wide, very big brained, snoutless, largely furless, and perched on a short, nearly vertical neck. Daniel E. Lieberman sets out to explain how the human head works, and why our heads evolved in this peculiarly human way.
Exhaustively researched and years in the making, this innovative book documents how the many components of the head function, how they evolved since we diverged from the apes, and how they interact in diverse ways both functionally and developmentally, causing them to be highly integrated. This integration not only permits the head’s many units to accommodate each other as they grow and work, but also facilitates evolutionary change. Lieberman shows how, when, and why the major transformations evident in the evolution of the human head occurred. The special way the head is integrated, Lieberman argues, made it possible for a few developmental shifts to have had widespread effects on craniofacial growth, yet still permit the head to function exquisitely.
This is the first book to explore in depth what happened in human evolution by integrating principles of development and functional morphology with the hominin fossil record. The Evolution of the Human Head will permanently change the study of human evolution and has widespread ramifications for thinking about other branches of evolutionary biology.
It has been known for more than a century that men and women tend to differ in the relative lengths of their index (2D) and ring (4D) fingers, which upon casual observation seem fairly symmetrical. Men on average have fourth digits longer than their second digits, while women typically have the opposite. Digit ratios are unique in that they are fixed before birth, while other sexually dimorphic variables are fixed after puberty, and the same genes that control for finger length also control the development of the sex organs. The 2D:4D ratio is the only prenatal sexually dimorphic trait that measurably explains conditions linking testosterone, estrogen, and human development; the study of the ratio broadens our view of human ability, talent, behavior, disposition, health, and fertility. In this book, Manning presents evidence for how 2D:4D correlates with traits ranging from sperm counts, family size, musical genius, and sporting prowess, to autism, depression, homosexuality, heart attacks, and breast cancer, traits that are all linked with early exposure to sex hormones.
Too tiny to see with the naked eye, the human embryo was just a hypothesis until the microscope made observation of embryonic development possible. This changed forever our view of the minuscule cluster of cells that looms large in questions about the meaning of life. Embryos under the Microscope examines how our scientific understanding of the embryo has evolved from the earliest speculations of natural philosophers to today’s biological engineering, with its many prospects for life-enhancing therapies. Jane Maienschein shows that research on embryos has always revealed possibilities that appear promising to some but deeply frightening to others, and she makes a persuasive case that public understanding must be informed by up-to-date scientific findings.
Direct observation of embryos greatly expanded knowledge but also led to disagreements over what investigators were seeing. Biologists confirmed that embryos are living organisms undergoing rapid change and are not in any sense functioning persons. They do not feel pain or have any capacity to think until very late stages of fetal development. New information about DNA led to discoveries about embryonic regulation of genetic inheritance, as well as evolutionary relationships among species. Scientists have learned how to manipulate embryos in the lab, taking them apart, reconstructing them, and even synthesizing—practically from scratch—cells, body parts, and maybe someday entire embryos. Showing how we have learned what we now know about the biology of embryos, Maienschein changes our view of what it means to be alive.
While “freaks” have captivated our imagination since well before the nineteenth century, the Victorians flocked to shows featuring dancing dwarves, bearded ladies, “missing links,” and six-legged sheep. Indeed, this period has been described by Rosemarie Garland-Thomson as the epoch of “consolidation” for freakery: an era of social change, enormously popular freak shows, and taxonomic frenzy. Victorian Freaks: The Social Context of Freakery in Britain, edited by Marlene Tromp, turns to that rich nexus, examining the struggle over definitions of “freakery” and the unstable and sometimes conflicting ways in which freakery was understood and deployed. As the first study centralizing British culture, this collection discusses figures as varied as Joseph Merrick, “The Elephant Man”; Daniel Lambert, “King of the Fat Men”; Julia Pastrana, “The Bear Woman”; and Laloo “The Marvellous Indian Boy” and his embedded, parasitic twin. The Victorian Freaks contributors examine Victorian culture through the lens of freakery, reading the production of the freak against the landscape of capitalist consumption, the medical community, and the politics of empire, sexuality, and art. Collectively, these essays ask how freakery engaged with notions of normalcy and with its Victorian cultural context.
Claude Bernard was recognized in his own time as one of the giants of science; today he still belongs among the dozen most significant scientists since 1800. Through his ability to present and interpret results within a persuasive theoretical framework, Bernard became an almost mythical example of the systematic, rational, and successful scientist.
This book examines Bernard's formative early research in the years from 1842 to 1848, before he became a well-known scientist, a revered sage, and, in the eyes of many, a “founder” of experimental physiology. Frederic Holmes's intimate description of Bernard's investigations is accompanied by a broad account of physiology and biochemistry in the era when they were becoming recognizably modern.
This second volume completes the story begun in Walter B. Cannon: The Life and Times of a Young Scientist (Belknap Press, 1987), tracing the middle and late years of one of America’s most distinguished medical scientists.
It resumes during World War II with Cannon’s battlefield work on traumatic shock in England and France, and follows him to Harvard Medical School as he investigated the workings of the sympathetic division of the autonomic nervous system, reaffirmed his emergency theory of the sympathico-adrenal system, and developed his now-famous concept of homeostasis and pioneer contributions to the newly emerging field of neuroendocrinology. This volume also recounts Cannon’s work with society on a broader scale, including defending the practice of animal experimentation, the rescue of European medical émigrés fleeing the Nazis and Fascists, and providing medical aid to the Spanish Loyalists and to China. Moreover, as a senior statesman of science, Cannon helped guide policies and programs that shaped the future of medical research, practice, and education.
The alarm calls of birds make them difficult for predators to locate, while the howl of wolves and the croak of bullfrogs are designed to carry across long distances. From an engineer's perspective, how do such specialized adaptations among living things really work? And how does physics constrain evolution, channeling it in particular directions?
Writing with wit and a richly informed sense of wonder, Denny and McFadzean offer an expert look at animals as works of engineering, each exquisitely adapted to a specific manner of survival, whether that means spinning webs or flying across continents or hunting in the dark-or writing books. This particular book, containing more than a hundred illustrations, conveys clearly, for engineers and nonengineers alike, the physical principles underlying animal structure and behavior.
Pigeons, for instance-when understood as marvels of engineering-are flying remote sensors: they have wideband acoustical receivers, hi-res optics, magnetic sensing, and celestial navigation. Albatrosses expend little energy while traveling across vast southern oceans, by exploiting a technique known to glider pilots as dynamic soaring. Among insects, one species of fly can locate the source of a sound precisely, even though the fly itself is much smaller than the wavelength of the sound it hears. And that big-brained, upright Great Ape? Evolution has equipped us to figure out an important fact about the natural world: that there is more to life than engineering, but no life at all without it.
Our Marvelous Bodies offers a unique perspective on the structure, function, and care of the major systems of the human body. Unlike other texts that use a strictly scientific approach, physiologist Gary F. Merrill relays medical facts alongside personal stories that help students relate to and apply the information.
Readers learn the basics of feedback control systems, homeostasis, and physiological gradients. These principles apply to an understanding of the body’s functioning under optimal, healthy conditions, and they provide insight into states of acute and chronic illness. Separate chapters are devoted to each of the body’s systems in detail: nervous, endocrine, cardiovascular, respiratory, renal, gastrointestinal, musculoskeletal, reproductive, and immune. Through a series of real-life examples, the book also shows the importance of maintaining careful medical records for health care professionals, scientists, and patients alike.
How does contemporary science contribute to our understanding about what it means to be women or men? What are the social implications of scientific claims about differences between "male" and "female" brains, hormones, and genes? How does culture influence scientific and medical research and its findings about human sexuality, especially so-called normal and deviant desires and behaviors? Gender and the Science of Difference examines how contemporary science shapes and is shaped by gender ideals and images.
Prior scholarship has illustrated how past cultures of science were infused with patriarchal norms and values that influenced the kinds of research that was conducted and the interpretation of findings about differences between men and women. This interdisciplinary volume presents empirical inquiries into today's science, including examples of gendered scientific inquiry and medical interventions and research. It analyzes how scientific and medical knowledge produces gender norms through an emphasis on sex differences, and includes both U.S. and non-U.S. cases and examples.
Female and male brains are different, thanks to hormones coursing through the brain before birth. That’s taught as fact in psychology textbooks, academic journals, and bestselling books. And these hardwired differences explain everything from sexual orientation to gender identity, to why there aren’t more women physicists or more stay-at-home dads.
In this compelling book, Rebecca Jordan-Young takes on the evidence that sex differences are hardwired into the brain. Analyzing virtually all published research that supports the claims of “human brain organization theory,” Jordan-Young reveals how often these studies fail the standards of science. Even if careful researchers point out the limits of their own studies, other researchers and journalists can easily ignore them because brain organization theory just sounds so right. But if a series of methodological weaknesses, questionable assumptions, inconsistent definitions, and enormous gaps between ambiguous findings and grand conclusions have accumulated through the years, then science isn’t scientific at all.
Elegantly written, this book argues passionately that the analysis of gender differences deserves far more rigorous, biologically sophisticated science. “The evidence for hormonal sex differentiation of the human brain better resembles a hodge-podge pile than a solid structure…Once we have cleared the rubble, we can begin to build newer, more scientific stories about human development.”
One scarcely knows whether to laugh or cry. The spectacle presented, in Cynthia Russett's splendid book, of nineteenth-century white male scientists and thinkers earnestly trying to prove women inferior to men--thereby providing, along with "savages" and "idiots," an evolutionary buffer between men and animals--is by turns appalling, amusing, and saddening. Surveying the work of real scientists as well as the products of more dubious minds, Russett has produced a learned yet immensely enjoyable chapter in the annals of human folly.
At the turn of the century science was successfully challenging the social authority of religion; scientists wielded a power no other group commanded. Unfortunately, as Russett demonstrates, in Victorian sexual science, empiricism tangled with prior belief, and scientists' delineation of the mental and physical differences between men and women was directed to show how and why women were inferior to men. These men were not necessarily misogynists. This was an unsettling time, when the social order was threatened by wars, fierce economic competition, racial and industrial conflict, and the failure of society to ameliorate poverty, vice, crime, illnesses. Just when men needed the psychic lift an adoring dependent woman could give, she was demanding the vote, higher education, and the opportunity to become a wage earner!
No other work has treated this provocative topic so completely, nor have the various scientific theories used to marshal evidence of women's inferiority been so thoroughly delineated and debunked. Erudite enough for scholars in the history of science, intellectual history, and the history of women, this book with its stylish presentation will also attract a large nonspecialist audience.
Eighteenth-century natural historians created a peculiar, and peculiarly durable, vision of nature—one that embodied the sexual and racial tensions of that era. When plants were found to reproduce sexually, eighteenth-century botanists ascribed to them passionate relations, polyandrous marriages, and suicidal incest, and accounts of steamy plant sex began to infiltrate the botanical literature of the day. Naturalists also turned their attention to the great apes just becoming known to eighteenth-century Europeans, clothing the females in silk vestments and training them to sip tea with the modest demeanor of English matrons, while imagining the males of the species fully capable of ravishing women.
Written with humor and meticulous detail, Nature’s Body draws on these and other examples to uncover the ways in which assumptions about gender, sex, and race have shaped scientific explanations of nature. Schiebinger offers a rich cultural history of science and a timely and passionate argument that science must be restructured in order to get it right.
Winner of a British Medical Association Book Award
A Brain Pickings Best Science Book of the Year
Early birds and night owls are born, not made. Sleep patterns may be the most obvious manifestation of the highly individualized biological clocks we inherit, but these clocks also regulate bodily functions from digestion to hormone levels to cognition. Living at odds with our internal timepieces, Till Roenneberg shows, can make us chronically sleep deprived and more likely to smoke, gain weight, feel depressed, fall ill, and fail geometry. By understanding and respecting our internal time, we can live better.
“Internal Time is a cautionary tale—actually a series of 24 tales, not coincidentally. Roenneberg ranges widely from the inner workings of biological rhythms to their social implications, illuminating each scientific tutorial with an anecdote inspired by clinical research...Written with grace and good humor, Internal Time is a serious work of science incorporating the latest research in chronobiology...[A] compelling volume.”
—A. Roger Ekirch, Wall Street Journal
“This is a fascinating introduction to an important topic, which will appeal to anyone who wishes to delve deep into the world of chronobiology, or simply wonders why they struggle to get a good night’s sleep.”
—Richard Wiseman, New Scientist
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