front cover of Breaking the Vicious Circle
Breaking the Vicious Circle
Toward Effective Risk Regulation
Stephen Breyer
Harvard University Press, 1993
Breaking the Vicious Circle is a tour de force that should be read by everyone who is interested in improving our regulatory processes. Written by a highly respected federal judge, who would go on to serve on the Supreme Court, and who obviously recognizes the necessity of regulation but perceives its failures and weaknesses as well, it pinpoints the most serious problems and offers a creative solution that would for the first time bring rationality to bear on the vital issue of priorities in our era of limited resources.
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front cover of Evolution in a Toxic World
Evolution in a Toxic World
How Life Responds to Chemical Threats
Emily Monosson
Island Press, 2012
With BPA in baby bottles, mercury in fish, and lead in computer monitors, the world has become a toxic place. But as Emily Monosson demonstrates in her groundbreaking new book, it has always been toxic. When oxygen first developed in Earth's atmosphere, it threatened the very existence of life: now we literally can't live without it. According to Monosson, examining how life adapted to such early threats can teach us a great deal about today's (and tomorrow's) most dangerous contaminants. While the study of evolution has advanced many other sciences, from conservation biology to medicine, the field of toxicology has yet to embrace this critical approach.
In Evolution in a Toxic World, Monosson seeks to change that. She traces the development of life's defense systems—the mechanisms that transform, excrete, and stow away potentially harmful chemicals—from more than three billion years ago to today. Beginning with our earliest ancestors' response to ultraviolet radiation, Monosson explores the evolution of chemical defenses such as antioxidants, metal binding proteins, detoxification, and cell death. 
 
As we alter the world's chemistry, these defenses often become overwhelmed faster than our bodies can adapt. But studying how our complex internal defense network currently operates, and how it came to be that way, may allow us to predict how it will react to novel and existing chemicals. This understanding could lead to not only better management and preventative measures, but possibly treatment of current diseases. Development of that knowledge starts with this pioneering book.
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In Search of Safety
Chemicals and Cancer Risk
John D. Graham, Laura C. Green, and Marc J. Roberts
Harvard University Press, 1988

Most public controversies about the effects of chemicals on human health revolve around the risk of cancer—hardly surprising, considering that it is the second leading cause of death in the United States. People are concerned about the dangers of carcinogens in air, water, and food, and they expect their representatives in government to protect them from such hazards. On the other hand, the economic costs of eliminating every suspected carcinogen from the environment would cause tremendous economic hardship. How should policymakers use science to help strike a balance between the benefits of lowering the risk of cancer and the economic costs of regulation?

In this important book the authors squarely address the complex interaction of science and regulatory policy. They begin by clarifying the scientific issues that are central to regulatory decisions, then explain how and why scientists can honestly disagree about these issues. They demonstrate with two cogent case studies: the heated debates about formaldehyde and benzene, both useful but potentially toxic chemicals. By examining how scientists evaluated the risks from these chemicals, and what kinds of legislative, administrative, and judicial decisions emerged from the evaluations, the authors furnish insight into the checks and balances of health-risk regulation.

They point out that overselling science in this context is harmful to both science and democracy. Their final chapter proposes creative methods for constructing a bridge between the scientist and the regulator that will be invaluable to anyone concerned about health risks.

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Learning about Risk
Consumer and Worker Responses to Hazard Information
W. Kip Viscusi and Wesley A. Magat
Harvard University Press, 1987

How do people decide whether or not to take chances with their health and safety? Do they pay attention to warnings about hazardous products used at home or on the job? What is the best way to present this information? These questions are becoming increasingly important as direct government regulation is replaced by programs to educate workers and consumers about risk. Information itself is becoming a regulatory device, but until now little has been known about its use and effectiveness.

Learning about Risk offers important new evidence on how people process information about risk and how they make choices under uncertainty. Drawing on work in a variety of disciplines—economics, decision science, marketing, and psychology—as well as on extensive original survey data, the authors take a close look at one type of risk information: the labeling of hazardous products and chemicals. They use the word labeling to mean all the tangible ways in which information is transmitted, including not merely warnings on bottles and cans but also leaflets and brochures, signs in the workplace, and store displays. The authors surveyed hundreds of consumers and chemical workers to explore a range of issues—the accuracy and appropriateness of people's risk assessments, the types of precautions they take, the values they attach to these measures, the wages they expect for performing risky jobs, and the relationship between the precaution taken and the content, wording, and format of the warning.

Overall, the authors show that information policies are a promising approach to controlling risks in the marketplace and on the job. Their findings will be of interest to government officials, policy analysts, economists, psychologists, and managers concerned professionally with the labeling of hazardous products.

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Residues
Thinking Through Chemical Environments
Soraya Boudia
Rutgers University Press, 2022
Residues offers readers a new approach for conceptualizing the environmental impacts of chemicals production, consumption, disposal, and regulation. Environmental protection regimes tend to be highly segmented according to place, media, substance, and effect; academic scholarship often reflects this same segmented approach. Yet, in chemical substances we encounter phenomena that are at once voluminous and miniscule, singular and ubiquitous, regulated yet unruly. Inspired by recent studies of materiality and infrastructures, we introduce “residual materialism” as a framework for attending to the socio-material properties of chemicals and their world-making powers. Tracking residues through time, space, and understanding helps us see how the past has been built into our present chemical environments and future-oriented regulatory systems, why contaminants seem to always evade control, and why the Anthropocene is as inextricably harnessed to the synthesis of carbon into new molecules as it is driven by carbon’s combustion.
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front cover of Unnatural Selection
Unnatural Selection
How We Are Changing Life, Gene by Gene
Emily Monosson
Island Press, 2015
Gonorrhea. Bed bugs. Weeds. Salamanders. People. All are evolving, some surprisingly rapidly, in response to our chemical age. In Unnatural Selection, Emily Monosson shows how our drugs, pesticides, and pollution are exerting intense selection pressure on all manner of species. And we humans might not like the result.

Monosson reveals that the very code of life is more fluid than once imagined. When our powerful chemicals put the pressure on to evolve or die, beneficial traits can sweep rapidly through a population. Species with explosive population growth—the bugs, bacteria, and weeds—tend to thrive, while bigger, slower-to-reproduce creatures, like ourselves, are more likely to succumb.

Monosson explores contemporary evolution in all its guises. She examines the species that we are actively trying to beat back, from agricultural pests to life-threatening bacteria, and those that are collateral damage—creatures struggling to adapt to a polluted world. Monosson also presents cutting-edge science on gene expression, showing how environmental stressors are leaving their mark on plants, animals, and possibly humans for generations to come. 

Unnatural Selection is eye-opening and more than a little disquieting. But it also suggests how we might lessen our impact: manage pests without creating super bugs; protect individuals from disease without inviting epidemics; and benefit from technology without threatening the health of our children.
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