This fascinating study in the sociology of science explores the way scientists conduct, and draw conclusions from, their experiments. The book is organized around three case studies: replication of the TEA-laser, detecting gravitational rotation, and some experiments in the paranormal.

"In his superb book, Collins shows why the quest for certainty is disappointed. He shows that standards of replication are, of course, social, and that there is consequently no outside standard, no Archimedean point beyond society from which we can lever the intellects of our fellows."—Donald M. McCloskey, Journal of Economic Psychology

"Collins is one of the genuine innovators of the sociology of scientific knowledge. . . . Changing Order is a rich and entertaining book."—Isis

"The book gives a vivid sense of the contingent nature of research and is generally a good read."—Augustine Brannigan, Nature

"This provocative book is a review of [Collins's] work, and an attempt to explain how scientists fit experimental results into pictures of the world. . . . A promising start for new explorations of our image of science, too often presented as infallibly authoritative."—Jon Turney, New Scientist

Charles Brenton Huggins won the Nobel prize in 1966 for his extensive work in cancer research. He has spent fifty years at the laboratory bench exploring the nature of this disease in an attempt to understand and control it. In this volume, based almost exclusively on experiments conducted over the past twenty years at the University of Chicago, is both the record of Huggins's own research and, in Huggins's words, "a do-it-yourself guide for cancer research workers." Written simply and clearly so that the experiments can be easily reproduced, the book presents Huggins's experiments in the induction of breast cancer and leukemia in rodents. It also describes the methods he discovered to prevent cancer and to cure many of the cancers he has been able to induce. Although most of the material concerns breast cancer and leukemia, research on other kinds of tumors is also described.