The major goal of developmental neurobiology is to understand how the nervous system is put together. A central theme that has emerged from research in this field over the last several decades is the crucial role of trophic interactions in neural assembly, and indeed throughout an animal's life. Trophic—which means nutritive—refers to long-term interdependencies between nerve cells and the cells they innervate.

The theory of trophic effects presented in this book offers an explanation of how the vertebrate nervous system is related to—and regulated by—the body it serves. The theory rationalizes the nervous system's accommodation, throughout life, to the changing size and form of the body it tenants, indicating the way connections between nerve cells change in response to stimuli as diverse as growth, injury, experience, and natural selection.

Dale Purves, a leading neurobiologist best known for his work on the formation and maintenance of synaptic connections, presents this theory within the historical setting of earlier ideas about neural organization—from Weiss's theory of functional reorganization to the chemoaffinity theory championed by Sperry. In addition to illuminating eighty years of work on trophic interactions, this book asks its own compelling questions: Are trophic interactions characteristic of all animals or only of those with complex nervous systems? Are trophic interactions related to learning? What does the trophic theory of neural connections imply about the currently fashionable view that the nervous system operates according to Darwinian principles?

Purves lays the theoretical foundation for practical exploration of trophic interactions as they apply to neural connections, a pursuit that will help us understand how our own nervous systems generate change. The ideas in this book not only enrich neurobiology but also convey the profound relevance of neuroscience to other fields of life science.

From simple reflexes to complex choreographies of movement, all animal behavior is governed by a nervous system. But what kind of government is it—a dictatorship or a democracy?

Nervous systems consist of circuits of interconnected nerve cells (neurons) that transmit and receive information via electrical signals. Every moment, each neuron adds up stimulating and inhibiting inputs from many other neurons to determine whether to send an electrical signal to its recipients. Some circuits are dominated by a single “dictator” neuron that gathers information from many sources and then issues commands, such as the Mauthner neuron that triggers escape in fish. In other more “democratic” circuits, such as those mediating eye movements in monkeys, the outcome is determined by a tally of “votes” from a large population of neurons. Rhythmic movements like breathing and locomotion are generated by “government programs” within the central nervous system, but modified by a soup of chemicals and by free market–like feedback from sensory neurons. Nervous systems also use sophisticated surveillance of the surrounding environment and keep track of their own decisions in order to avoid internal conflicts. Nervous systems are not restricted to using one set of procedures at a time. They have evolved over long periods to control behaviors in whichever ways are most effective, and they essentially combine multiple forms of government simultaneously.

Engaging and accessible, Governing Behavior explains the variety of structures and strategies that control behavior, while providing an overview of thought-provoking debates and cutting-edge research in neurobiology.