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A Brief History of the Harvard University Cyclotrons
Richard Wilson
Harvard University Press, 2004
In 1937, Harvard University built its first cyclotron, which was subsequently requisitioned by the U.S. Army and taken to Los Alamos in 1943. The second cyclotron, one of the world's longest-running accelerators, was finished in 1949 and operated until 2002. In its first 20 years, the cyclotron's primary use was for nuclear physics, particularly for understanding the interaction between two nucleons. During the next 30 years, the emphasis switched to treating patients with proton radiotherapy. A total of 9,115 patients were treated by this method and the treatment has been copied all over the world. This book describes the work of the Harvard cyclotron during its 50 years of operation and includes references to about 500 publications and 40 student theses from the work.
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front cover of Precision Radiation Oncology
Precision Radiation Oncology
Haffty, Bruce G
Rutgers University Press, 2018
Precision medicine is a rapidly-evolving field in the management of cancer. The use of novel molecular or genetic signatures in local-regional management is still in its infancy. Precision Radiation Oncology demystifies this state-of-the-art research and technology. 

By describing current existing clinical and pathologic features, and focusing on the ability to improve outcomes in cancer using radiation therapy, this book discusses incorporating novel genomic- or biology-based biomarkers in the treatment of patients moving radiation oncology into precision/personalized medicine. Precision Radiation Oncology provides readers with an overview of the new developments of precision medicine in radiation oncology, further advancing the integration of new research findings into individualized radiation therapy and its clinical applications.  
 
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front cover of Radiation Evangelists
Radiation Evangelists
Technology, Therapy, and Uncertainty at the Turn of the Century
Jeffrey Womack
University of Pittsburgh Press, 2020
Radiation Evangelists explores X-ray and radium therapy in the United States and Great Britain during a crucial period of its development, from 1896 to 1925. It focuses on the pioneering work of early advocates in the field, the “radiation evangelists” who, motivated by their faith in a new technology, trust in new energy sources, and hope for future breakthroughs, turned a blind eye to the dangers of radiation exposure. Although ionizing radiation effectively treated diseases like skin infections and cancers, radiation therapists—who did not need a medical education to develop or administer procedures or sell tonics containing radium—operated in a space of uncertainty about exactly how radiation worked or would affect human bodies. And yet radium, once a specialized medical treatment, would eventually become a consumer health product associated with the antibacterial properties of sunlight.

This book raises important questions about medical experimentation and the so-called Golden Rule of medical ethics, issues of safety and professional identity, and the temptation of a powerful therapeutic tool that also posed significant risks in its formative years. In this cautionary tale of technological medical progress, Jeffrey Womack reveals how practitioners and their patients accepted uncertainty as a condition of their therapy in an attempt to alleviate human suffering.
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