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In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms.

Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences.

Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf

Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present.

Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history.

This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

"The many diseases that are endemic in most of the developing nations of the world (and that may also affect travelers to these regions) are, at world levels, the most important sources of morbidity that affect the entire human race. The change in morbidity patterns in the more developed nations should not be permitted to blind the more affluent countries to the implications of this simple statement. Thus, direct and useful guides are needed to assure efficient and economical diagnosis and treatment of those infections that are endemic to the less affluent two-thirds of the earth.

"The algorithms in this book have been developed by Drs. Warren and Mahmoud, as the result of a systematic effort to produce such guides. The book is presented as another in the series "Studies in Infectious Disease Research" and is a most welcome addition, certain to supply a major and hitherto inadequately fulfilled need."—from the Foreword, by Edward H. Kass, M. D., Ph.D

Global Health in Africa is a first exploration of selected histories of global health initiatives in Africa. The collection addresses some of the most important interventions in disease control, including mass vaccination, large-scale treatment and/or prophylaxis campaigns, harm reduction efforts, and nutritional and virological research.The chapters in this collection are organized in three sections that evaluate linkages between past, present, and emergent. Part I, “Looking Back,” contains four chapters that analyze colonial-era interventions and reflect upon their implications for contemporary interventions. Part II, “The Past in the Present,” contains essays exploring the historical dimensions and unexamined assumptions of contemporary disease control programs. Part III, “The Past in the Future,” examines two fields of public health intervention in which efforts to reduce disease transmission and future harm are premised on an understanding of the past.

This much-needed volume brings together international experts from the disciplines of demography, anthropology, and historical epidemiology. Covering health initiatives from smallpox vaccinations to malaria control to HIV campaigns, Global Health in Africa offers a first comprehensive look at some of global health’s most important challenges.

In this lesson-packed book, Mark Nichter, one of the world’s leading medical anthropologists, summarizes what more than a quarter-century of health social science research has contributed to international health and elucidates what social science research can contribute to global health and the study of biopolitics in the future. Nichter focuses on our cultural understanding of infectious and vector-borne diseases, how they are understood locally, and how various populations respond to public health interventions.

The book examines the perceptions of three groups whose points of view on illness, health care, and the politics of responsibility often differ and frequently conflict: local populations living in developing countries, public health practitioners working in international health, and health planners/policy makers. The book is written for both health social scientists working in the fields of international health and development and public health practitioners interested in learning practical lessons they can put to good use when engaging communities in participatory problem solving.

Global Health critically examines representations that frame international health discourse. It also addresses the politics of what is possible in a world compelled to work together to face emerging and re-emerging diseases, the control of health threats associated with political ecology and defective modernization, and the rise of new assemblages of people who share a sense of biosociality. The book proposes research priorities for a new program of health social science research. Nichter calls for greater involvement by social scientists in studies of global health and emphasizes how medical anthropologists in particular can better involve themselves as scholar activists.

The development of medicine in Southeast Asia over the past two centuries has not been a simple imposition of European scientific medicine, but a complex and negotiated process that drew on Southeast Asian health experts, local medical traditions, and changing national and popular expectations. The contributors to this volume show how the practices of health in Southeast Asia over the past two centuries were mediated by local medical traditions, colonial interests, governments and policies, international interventions, and by a wide range of health agents and intermediaries. Their findings call into question many of the claims based on medicalization and biopolitics that treat change as a process of rupture. While governments, both colonial and national, instituted policies that affected large numbers of people, much health care remained rooted in a more interactive and locally-mediated experience, in which tradition, adaptation and hybridization is as important as innovation and conflict. "Semi-subaltern" Western-trained doctors and varied traditional healers, many of them women, were among the cultural brokers involved in the building of healthcare systems, and helped circulate mixed practices and ideas about medicine and health even as they found their place in new professional and social hierarchies in an era of globalization.

Illness provides a mirror that allows sufferers to see themselves and to become more introspective. As they struggle for control over illness and control over time, they also struggle to control the central images of the self. For example, the chronically ill may situate their self-concepts in the past, present, or future. Charmaz examines under what conditions they situate their self-concepts in each of those timeframes. People may say they live one day at a time. They may bracket certain experiences, such as a heart attack, as timemarkers or turning points in the past. Or they may look ahead to recovering their health. Or ahead to death. 

Charmaz artfully combines near jargon-free analysis with moving stories about how people have experienced illness, usually told in the sufferers' own words. She enters the world of the chronically ill, and brings us into it.

As local governments and organizations assume more responsibility for ensuring the public health, identity politics play an increasing yet largely unexamined role in public and policy attitudes toward local problems. In Governing How We Care, medical anthropologist Susan Shaw examines the relationship between government and citizens using case studies of needle exchange and Welfare-to-Work programs to illustrate the meanings of cultural difference, ethnicity, and inequality in health care.

Drawing on ethnographic research conducted over six years in a small New England city, Shaw presents critical perspectives on public health intervention efforts. She looks at online developments in health care and makes important correlations between poverty and health care in the urban United States. Shaw also highlights the new concepts of community and forms of identity that emerge in our efforts to provide effective health care. Governing How We Care shows how government-sponsored community health and health care programs operate in an age of neoliberalism.

A masterpiece by one of the West’s best-loved authorsJust when Sacramento journalist Marty Martinez thinks his life can’t get any worse, it does. His beloved son has died of AIDS, his wife has divorced him and joined a cult, and his daughter blames him for the disintegration of their family. Then a chance medical examination reveals that he has prostate cancer. Marty faces his new role as a cancer patient with awkward grit and desperation. He is a sympathetic, utterly convincing character seeking faith in a Catholic Church as troubled as he is. He brings increased intensity to his career as he investigates a far-reaching political scandal, reunites his family in unexpected ways, and finds love with a fellow cancer patient. Grace Period is a profound and sometimes hilarious novel about living with serious illness. Marty copes with fear and the painful, sometimes embarrassing, treatment of his disease, but instead of winding down his life he finds fresh purpose and a joyful new love. Haslam brilliantly depicts the complexities of everyday life and the intricate, sometimes tortured bonds of family and friendship. In Grace Period, Haslam shows us that existence at the precarious edge of life offers not only pain and loss but hope, a chance at redemption, love, and even happiness. Grace Period is his masterwork.

The “miracle drug” penicillin was first administered in Oxford in February 1941, leading to a full-blown transformation in the way bacterial infection was diagnosed and treated. What was to become one of the greatest stories of the “golden age of medical discovery” not only had its roots in Oxford, but was the latest in a line of pivotal medical discoveries made in the city.
           
Great Medical Discoveries offers a short illustrated history of the city’s contribution to the medical sciences, from the medieval period to the present day, when it is home to some of the world’s leading large scientific institutions. In charting this remarkable history, the book showcases twenty discoveries across the centuries. In the mid-twentieth century, for instance, Oxford led the field of experimental medicine, and William Harvey, Thomas Willis, and Thomas Sydenham all gained eponymous status with their pioneering research into the workings of the human body. In the mid-seventeenth century, Dorothy Hodgkin’s development of x-ray crystallography earned her a Nobel Prize in Chemistry. Meanwhile, the work of epidemiologist Richard Doll saved millions of lives by making clear the long-term dangers of smoking and the benefits of quitting.
           
Great Medical Discoveries traces these and other examples of groundbreaking research—from the scientific application of anesthetics to new treatments for hemophilia and life-saving advances in neurosurgery—and shows how they form part of a wider tapestry of work that has helped shape the medical sciences and improve human health.