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4 books match the query 'Human Health'

cover of Crab Wars: A Tale of Horseshoe Crabs, Bioterrorism, and Human Health

Crab Wars

A Tale of Horseshoe Crabs, Bioterrorism, and Human Health

William Sargent

University Press of New England, 2006

Surviving almost unmolested for 300 million years, the horseshoe crab is now the object of an intense legal and ethical struggle involving marine biologists, environmentalists, US government officials, biotechnologists, and international corporations. The source of this friction is the discovery 25 years ago that the blood of these ancient creatures serves as the basis for the most reliable test for the deadly and ubiquitous gram-negative bacteria. These bacteria are responsible for life-threatening diseases like menengitis, typhoid, E. coli, Legionnaire’s Disease and toxic shock syndrome. Because every drug certified by the FDA must be tested using the horseshoe crab derivative known as Limulus lysate, a multimillion dollar industry has emerged involving the license to “bleed” horseshoe crabs and the rights to their breeding grounds. Since his youthful fascination with these ancient creatures, William Sargent has spent much of his life observing, studying, and collecting horseshoe crabs. As a result, he presents a thoroughly accessible insider’s guide to the discovery of the lysate test, the exploitation of the crabs at the hands of multinational pharmaceutical conglomerates, local fishing interests, and the legal and governmental wrangling over the creatures’ ultimate fate. In the end, the story of the horseshoe crab is a sobering reflection on the unintended consequences of scientific progress and the danger of self-regulated industries controlling a limited natural resource.
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cover of Crab Wars: A Tale of Horseshoe Crabs, Ecology, and Human Health

Crab Wars

A Tale of Horseshoe Crabs, Ecology, and Human Health

William Sargent

Brandeis University Press, 2021

A timely look at the exploitation of a species that has helped with the development of countless drugs and is fast becoming endangered.
 
Because every drug certified by the FDA must be tested using the horseshoe crab derivative known as Limulus lysate, a multimillion-dollar industry has emerged involving the license to bleed horseshoe crabs and the rights to their breeding grounds. William Sargent presents a thoroughly accessible insider’s guide to the discovery of the lysate test, the exploitation of the horseshoe crab at the hands of multinational pharmaceutical conglomerates, local fishing interests, and the legal and governmental wrangling over the creatures’ ultimate fate. In the end, the story of the horseshoe crab is a sobering reflection on the unintended consequences of scientific progress and the danger of self-regulated industries controlling a limited natural resource. This new edition brings the story up to date as companies race to manufacture alternatives to the horseshoe crab blood, which is now essential for testing vaccines such as those developed to counter COVID-19. However, horseshoe crab populations are still dwindling, with profound implications not only for the future of the crabs themselves but also for the ecosystems that depend on them.
 
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cover of Our Marvelous Bodies: An Introduction to the Physiology of Human Health

Our Marvelous Bodies

An Introduction to the Physiology of Human Health

Merrill, Gary F

Rutgers University Press, 2008

Our Marvelous Bodies offers a unique perspective on the structure, function, and care of the major systems of the human body. Unlike other texts that use a strictly scientific approach, physiologist Gary F. Merrill relays medical facts alongside personal stories that help students relate to and apply the information.

Readers learn the basics of feedback control systems, homeostasis, and physiological gradients. These principles apply to an understanding of the body’s functioning under optimal, healthy conditions, and they provide insight into states of acute and chronic illness. Separate chapters are devoted to each of the body’s systems in detail: nervous, endocrine, cardiovascular, respiratory, renal, gastrointestinal, musculoskeletal, reproductive, and immune. Through a series of real-life examples, the book also shows the importance of maintaining careful medical records for health care professionals, scientists, and patients alike.

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cover of To Raise Up the Man Farthest Down: Tuskegee University’s Advancements in Human Health, 1881–1987

To Raise Up the Man Farthest Down

Tuskegee University’s Advancements in Human Health, 1881–1987

Dana R. Chandler and Edith Powell

University of Alabama Press, 2018

An important historical account of Tuskegee University’s significant advances in health care, which affected millions of lives worldwide.

Alabama’s celebrated, historically black Tuskegee University is most commonly associated with its founding president, Booker T. Washington, the scientific innovator George Washington Carver, or the renowned Tuskegee Airmen. Although the university’s accomplishments and devotion to social issues are well known, its work in medical research and health care has received little acknowledgment. Tuskegee has been fulfilling Washington’s vision of “healthy minds and bodies” since its inception in 1881. In To Raise Up the Man Farthest Down, Dana R. Chandler and Edith Powell document Tuskegee University’s medical and public health history with rich archival data and never-before-published photographs. Chandler and Powell especially highlight the important but largely unsung role that Tuskegee University researchers played in the eradication of polio, and they add new dimension and context to the fascinating story of the HeLa cell line that has been brought to the public’s attention by popular media.

Tuskegee University was on the forefront in providing local farmers the benefits of agrarian research. The university helped create the massive Agricultural Extension System managed today by land grant universities throughout the United States. Tuskegee established the first baccalaureate nursing program in the state and was also home to Alabama’s first hospital for African Americans. Washington hired Alabama’s first female licensed physician as a resident physician at Tuskegee. Most notably, Tuskegee was the site of a remarkable development in American biochemistry history: its microbiology laboratory was the only one relied upon by the National Foundation for Infantile Paralysis (the organization known today as the March of Dimes) to produce the HeLa cell cultures employed in the national field trials for the Salk and Sabin polio vaccines. Chandler and Powell are also interested in correcting a long-held but false historical perception that Tuskegee University was the location for the shameful and infamous US Public Health Service study of untreated syphilis.

Meticulously researched, this book is filled with previously undocumented information taken directly from the vast Tuskegee University archives. Readers will gain a new appreciation for how Tuskegee’s people and institutions have influenced community health, food science, and national medical life throughout the twentieth century.

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