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2 books match the query 'Microscope'

cover of Heredity under the Microscope: Chromosomes and the Study of the Human Genome

Heredity under the Microscope

Chromosomes and the Study of the Human Genome

Soraya de Chadarevian

University of Chicago Press, 2020

By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms.
 
Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.
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cover of The Microscope and the Eye: A History of Reflections, 1740-1870

The Microscope and the Eye

A History of Reflections, 1740-1870

Jutta Schickore

University of Chicago Press, 2007

The microscope’s technical capabilities and uses expanded dramatically in the early nineteenth century, when it emerged as an important tool for medical education and played a key role in the development of the cell theory, among other advancements. Focusing on the decades surrounding this crucial period, Jutta Schickore weaves a fascinating story of microscopy by tracing the entwined history of the eye and the optical instrument.

Concentrating on Great Britain and the German lands—home to the period’s most significant developments in microscopy—The Microscope and the Eye examines debates about such subjects as the legitimacy of human trespassing on the microcosm and the nature of light. Schickore also explores the microscope’s role in investigations of the finer structure of the eye and the workings of nerve fibers and the microscopists’ reflections on vision, illusion, artifacts, and the merits of instruments. Fully considering the epistemological, metaphysical, and methodological implications of this centuries-old relationship, The Microscope and the Eye will be an important contribution to the history of the life sciences, vision studies, and scientific methodology.
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