During the past ten years, several theories have been proposed on the origin of the diversity of antibodies. George P. Smith presents a critical study of these theories in this detailed treatment of immunological problems from the point of view of molecular genetics.
Mr. Smith uses a new and simplifying approach to this long-standing controversy. By a comprehensive computerized analysis of antibody amino acid sequences (particularly the myeloma proteins), the author traces their evolution and matches his results against the expectations of the various theories of diversity. He discusses at length the other types of evidence as well.
Mr. Smith also deals with the clonal specialization of cells to produce a single antibody, and the relationship of this specialization to the somatic joining of antibody half-genes, which is one of the immune system's most important peculiarities.
Introductory material is provided to make this work understandable to molecular geneticists not versed in immunology and to immunologists not versed in molecular genetics.
This is a timely book offering a succinct and coherent summary of the various lines of evidence in a confused and controversial field.
The Varieties of Religious Experience, first delivered as the Gifford Lectures in Edinburgh, was published in 1902 and quickly established itself as a classic. It ranks with its great predecessor, The Principles of Psychology, as one of William James's masterworks.
The book is not concerned with institutional religion. Its subtitle is "A Study in Human Nature," and James defines his subject as the feelings, acts, and experiences of individuals in relation to what they consider to be divine. His broad topics include the religion of healthy-mindedness; the sick soul; the divided self and its unification; conversion; saintliness; and mysticism. These and other phenomena are vividly documented by individual case histories--recorded in autobiographies, diaries, confessions, and similar writings--drawn from the whole range of world literature.
Constantly reprinted over the years, Varieties here appears for the first time in an edition prepared and annotated according to modern standards of textual scholarship. Manuscript material has been used to recover the form in which the last two lectures were originally delivered.
Ulysses S. Grant’s ingenious campaign to capture the last Confederate stronghold on the Mississippi River was one of the most decisive events of the Civil War and one of the most storied military expeditions in American history. The ultimate victory at Vicksburg effectively cut the Confederacy in two, gave control of the river to Union forces, and delivered a devastating blow from which the South never fully recovered. Editors Steven E. Woodworth and Charles D. Grear have assembled essays by prominent and emerging scholars, who contribute astute analysis of this famous campaign’s most crucial elements and colorful personalities.
Encompassed in this first of five planned volumes on the Vicksburg campaign are examinations of the pivotal events that comprised the campaign’s maneuver stage, from March to May of 1863. The collection sheds new light on Grant’s formidable intelligence network of former slaves, Mississippi loyalists, and Union spies; his now legendary operations to deceive and confuse his Confederate counterparts; and his maneuvers from the perspective of classic warfare. Also presented are insightful accounts of Grant’s contentious relationship with John A. McClernand during the campaign; interactions between hostile Confederate civilians and Union army troops; and the planning behind such battles as Grierson’s Raid, Port Gibson, Raymond, Jackson, Champion Hill, and Big Black River Bridge.
In contrast to past studies that focus narrowly on war and massacre, treat Native peoples as victims, and consign violence safely to the past, this interdisciplinary collection of essays opens up important new perspectives. While recognizing the long history of genocidal violence against Indigenous peoples, the contributors emphasize the agency of individuals and communities in genocide’s aftermath and provide historical and contemporary examples of activism, resistance, identity formation, historical memory, resilience, and healing. The collection also expands the scope of violence by examining the eyewitness testimony of women and children who survived violence, the role of Indigenous self-determination and governance in inciting violence against women, and settler colonialism’s promotion of cultural erasure and environmental destruction.
By including contributions on Indigenous peoples in the United States, Canada, the Pacific, Greenland, Sápmi, and Latin America, the volume breaks down nation-state and European imperial boundaries to show the value of global Indigenous frameworks. Connecting the past to the present, this book confronts violence as an ongoing problem and identifies projects that mitigate and push back against it.
The spell that the West has always exercised on the American people had its most intense impact on American literature and thought during the nineteenth century. Henry Nash Smith shows, with vast comprehension, the influence of the nineteenth-century West in all its variety and strength, in special relation to social, economic, cultural, and political forces. He traces the myths and symbols of the Westward movement such as the general notion of a Westward-moving Course of Empire, the Wild Western hero, the virtuous yeoman-farmer—in such varied nineteenth-century writings as Leaves of Grass, the great corpus of Dime Novels, and most notably, Frederick Jackson Turner’s The Frontier in American History. Moreover, he synthesizes the imaginative expression of Western myths and symbols in literature with their role in contemporary politics, economics, and society, embodied in such forms as the idea of Manifest Destiny, the conflict in the American mind between idealizations of primitivism on the one hand and of progress and civilization on the other, the Homestead Act of 1862, and public-land policy after the Civil War.
The myths of the American West that found their expression in nineteenth-century words and deeds remain a part of every American’s heritage, and Smith, with his insight into their power and significance, makes possible a critical appreciation of that heritage.
The collection is divided into four sections. The first explores historical approaches to technology in the silent film, French cinema during the transition era, the films of the so-called New Hollywood, and the post-production sound business. The second investigates the practice of the singing voice in diverse repertories such as Bergman's films, Eighties teen films, and girls' voices in Brave and Frozen. The third considers the auteuristic voice of the soundtrack in works by Kurosawa, Weir, and others. A last section on narrative and vococentrism moves from The Martian and horror film to the importance of background music and the state of the soundtrack at the end of vococentrism.
Contributors: Julie Brown, James Buhler, Marcia Citron, Eric Dienstfrey, Erik Heine, Julie Hubbert, Hannah Lewis, Brooke McCorkle, Cari McDonnell, David Neumeyer, Nathan Platte, Katie Quanz, Jeff Smith, Janet Staiger, and Robynn Stilwell
At the outbreak of the Civil War, Massachusetts native Gilbert Thompson joined the regular army, which assigned him to the engineer battalion, a unit that provided critical support for the Union military effort in building bridges and roads and surveying and producing maps. While serving, Thompson kept a journal that eventually filled three volumes. The author’s early education in a utopian community called Hopedale left him well read, affording a journal peppered with literary allusions. Once the war ended, Corporal Thompson added some postwar reflections to create a unified single volume, which editor Mark A. Smith has carefully arranged so that the reader can clearly distinguish between Thompson’s contemporary accounts and his postwar reminiscences. An accomplished artist and topographer, Thompson illustrated his journals, adding depth to his narrative with portraits of key figures, drawings of ordinary scenes such as soldiers playing chess, and sights of the war. Additionally, he collected photographs both during and after the war, many of which are included.
Thompson’s wartime musings and postwar recollections have much to offer. Few diaries contain glimpses into the workings of a highly specialized unit such as the engineer battalion, and Thompson’s skills in depicting daily camp life in both words and pictures provide a distinctive look at the Union Army during the Civil War as well as an insightful look into the human condition. In his 1879 introduction, Thompson writes, “I wonder how I wrote as much and as well, and am thankful I was so fortunate as to have the opportunity to do so.” Students of the Civil War will feel fortunate he did.
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