Ethnology comprises the seventh and eighth volumes in the Handbook of Middle American Indians, published in cooperation with the Middle American Research Institute of Tulane University under the general editorship of Robert Wauchope (1909–1979). The editor of the Ethnology volumes is Evon Z. Vogt (1918–2004), Professor of Anthropology in the Department of Social Relations, Harvard University.

These two books contain forty-three articles, all written by authorities in their field, on the ethnology of the Maya region, the southern Mexican highlands and adjacent regions, the central Mexican highlands, western Mexico, and northwest Mexico. Among the topics described for each group of Indians are the history of ethnological investigations, cultural and linguistic distributions, major postcontact events, population, subsistence systems and food patterns, settlement patterns, technology, economy, social organization, religion and world view, aesthetic and recreational patterns, life cycle and personality development, and annual cycle of life.

The volumes are illustrated with photographs and drawings of contemporary and early historical scenes of native Indian life in Mexico and Central America.

The Handbook of Middle American Indians was assembled and edited at the Middle American Research Institute of Tulane University with the assistance of grants from the National Science Foundation and under the sponsorship of the National Research Council Committee on Latin American Anthropology.