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It was only around 1800 that heredity began to enter debates among physicians, breeders, and naturalists. Soon thereafter it evolved into one of the most fundamental concepts of biology. Here Staffan Müller-Wille and Hans-Jörg Rheinberger offer a succinct cultural history of the scientific concept of heredity. They outline the dramatic changes the idea has undergone since the early modern period and describe the political and technological developments that brought about these changes.

Müller-Wille and Rheinberger begin with an account of premodern theories of generation, showing that these were concerned with the procreation of individuals rather than with hereditary transmission. The authors reveal that when hereditarian thinking first emerged, it did so in a variety of cultural domains, such as politics and law, medicine, natural history, breeding, and anthropology. Müller-Wille and Rheinberger then track theories of heredity from the late nineteenth century—when leading biologists considered it in light of growing societal concerns with race and eugenics—through the rise of classical and molecular genetics in the twentieth century, to today, as researchers apply sophisticated information technologies to understand heredity. What readers come to see from this exquisite history is why it took such a long time for heredity to become a prominent concept in the life sciences and why it gained such overwhelming importance in those sciences and the broader culture over the last two centuries.

An Epistemology of the Concrete brings together case studies and theoretical reflections on the history and epistemology of the life sciences by Hans-Jörg Rheinberger, one of the world’s foremost philosophers of science. In these essays, he examines the history of experiments, concepts, model organisms, instruments, and the gamut of epistemological, institutional, political, and social factors that determine the actual course of the development of knowledge. Building on ideas from his influential book Toward a History of Epistemic Things, Rheinberger first considers ways of historicizing scientific knowledge, and then explores different configurations of genetic experimentation in the first half of the twentieth century and the interaction between apparatuses, experiments, and concept formation in molecular biology in the second half of the twentieth century. He delves into fundamental epistemological issues bearing on the relationship between instruments and objects of knowledge, laboratory preparations as a special class of epistemic objects, and the note-taking and write-up techniques used in research labs. He takes up topics ranging from the French “historical epistemologists” Gaston Bachelard and Georges Canguilhem to the liquid scintillation counter, a radioactivity measuring device that became a crucial tool for molecular biology and biomedicine in the 1960s and 1970s. Throughout An Epistemology of the Concrete, Rheinberger shows how assemblages—historical conjunctures—set the conditions for the emergence of epistemic novelty, and he conveys the fascination of scientific things: those organisms, spaces, apparatuses, and techniques that are transformed by research and that transform research in turn.

Sous ce titre qui rend hommage à la pensée de Derrida, sont rassemblées des conférences tenues par le biologiste Hans-Jörg Rheinberger entre 1994 et 2007. Six textes aussi brefs que denses, nourris de vie de laboratoire et de philosophie franco-allemande – de Gaston Bachelard à Bruno Latour en passant par Martin Heidegger et Jacques Lacan –, qui donnent à voir un mouvement épistémologique sur le temps long. Tentant de faire dialoguer cet héritage philosophique avec la biologie moléculaire contemporaine, Itérations propose des variations sur l'inconnu et l'insoupçonné dans la recherche scientifique, et sur les systèmes expérimentaux comme contextes déterminants de la production des savoirs – cernant toujours les manifestations de l'Être comme écriture.
Excellente introduction à cette pensée de l'épistémologie historique, Itérations est l’un des prolongements les plus féconds de la pensée de Derrida.

Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives.
 
The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.