"Newman is a prominent among the historians of science who have shown how important alchemy was as a part of the serious 'chymistry' of Robert Boyle, Isaac Newton and their contemporaries. In this book, he looks at the divide between 'art,' which used to mean anything productive involving artifice and forethought, and 'nature,' as illuminated in discussions of, and laboratory and clinical practice in, alchemy. . . . Newman, a clear and graceful writer, keeps his goal in view. He is an initiate--tapping, testing and transmuting--until something different, still called alchemy, gradually takes shape."
— David Knight, Nature
"A clear and graceful writer.... Mr. Newman argues that most current debates about boundaries between nature and artifice, or boundaries between proper and improper scientific exploration, echo debates that run through the history of alchemy. Critics of alchemy argued that the natural world could not be replicated or improved and that such goals should not be pursued. Advocates found porous boundaries between nature that could be explored and tested."
— Ed Rothstein, New York Times
"With close attention to historical and textual detail that is never less than engaging, Newman unpicks the historical accidents and political machinations that led to alchemy's marginalisation, bringing sympathy, wit and imagination to his account."
— Simon Ings, New Scientist
"William R. Newman shows that debating the ethical limits of human meddling in nature--even over creating artificial life in the laboratory--has a remarkably long history, going back well before the scientific revolution."
— Eric Wargo, Washington Times
"Newman chooses the fascinating topic of alchemy as his case study in the long history of human efforts to breach the barriers between nature and human artifice. . . . A thought-provoking book. "
— Iwan Rhys Morus, Science
"Thesis aside, read this book for lurid, colorful detrails about such figures as Zosimos and Paracelsus."
— Choice
"By uncovering within scholasticism an alchemical lineage in which knowledge was made by making things, not merely by contemplating their essences, [Newman] is able to launch a powerful critique of a conventional wisdom that such an innovation had to wait for Francis Bacon."
— John Hedley Brooke, American Historical Review
""[The book] is rich in nuance and detail, but it is also readable. . . . For those interested in the history and cultural importance of alchemy, it is a must-read. If in a moment of scientific triumphalism one is tempted to ask, 'What are the humanities for?' this book answers the question. . . . Read Newman and you will understand why Newton was an alchemist and why, dear reader, if you are a chemist, you are one, too."
— Pedro J. Bernal, Journal of Chemical Education
One of the Wall Street Journal's "Five Best Science Books--2006"
“As William R. Newman reminds us in Promethean Ambitions, his fascinating history of alchemy, the failure to distinguish good science from bad has been a recipe for policy disaster for centuries. Newman shows that alchemists were more than dreamers trying to convert lead into gold. From 1200 to 1700, they followed trends in metaphysical fashion by trying to create tiny humans, called homunculi. One hears echoes of today’s cloning debates in the 16th-century wrangling over the moral status of these imaginary creatures.”
— Russell Seitz, Wall Street Journal
"Newman's book, a masterpiece of historical synthesis, leads the reader through all sorts of topics, including the shape-shifting of early modern witches, the possibility of demonic assistance in the creation of trompe-l'oeil effects, Leonardo da Vinci's pigment recipes. . . . The weaving of these threads into Newman's careful and scholarly explication of alchemy's history enlivens that history and validates alchemy as an important and influential contributor the the Western intellectual tradition."
— Kathleen R. Sands, Chemical Heritage
"Newman's book will reward readers interested or involved in biogenetics or bioengineering, as well as historians and philsophers of science. The former will find a background for contextualizing the ethical dilemmas they face; the latter will find a powerful example of their discipline at its most thoughtful."
— Walter W. Woodward, Historical Studies in the Physical and Biological Sciences
"Promethean Ambitions is extraordinarily rich in detail. . . . An important and ambitious book that will reward the careful reader."
— Peter J. Ramberg, Bulletin for the History of Chemistry
"Promethean Ambitions demonstrates Newman's mastery of the alchemical textual tradition; he is at his best when reconstructing the long afterlife of specific medieval arguments and showing how Renaissance artists and seventeenth-century natural philosophers alike engaged them even as they turned them to new ends....This erudite book is an important contribution to the intellectual history of art and nature in medieval and early modern Europe."
— Tara E. Nummedal, Journal of Interdisciplinary History
"In this important new book, William Newman uncovers the surprisingly long history of modern debates concerned with delineating the natural and the artificial by exploring the philosophical underpinnings of alchemy from the ancient world to the period of the Scientific Revolution. With his characteristic command of difficult primary sources and his flair for framing provocative, historically nuanced arguments based on formidable archival research, Newman succeeds in bringing together the ancient myth of Daedalus and the modern concerns about Dolly the cloned sheep."
— Deborah E. Harkness, Technology and Culture
"Newman's own ambitions in this volume verge on the Promethean, and there are points at which the sheer wealth of material under discussion threatens to overwhelm the coherence and comprehensibility of his arguments. However, given a work of such range and quality--deeply serious but often entertaining, challenging but never tendentious, erudite but eminently readable--it seems churlish to grumble about an embarrassment of rishes."
— John T. Young, Ambix