front cover of The Retina
The Retina
An Approachable Part of the Brain, Revised Edition
John E. Dowling
Harvard University Press, 2011

John Dowling’s The Retina, published in 1987, quickly became the most widely recognized introduction to the structure and function of retinal cells. In this Revised Edition, Dowling draws on twenty-five years of new research to produce an interdisciplinary synthesis focused on how retinal function contributes to our understanding of brain mechanisms.

The retina is a part of the brain pushed out into the eye during development. It retains many characteristics of other brain regions and hence has yielded significant insights on brain mechanisms. Visual processing begins there as a result of neuronal interactions in two synaptic layers that initiate an analysis of space, color, and movement. In humans, visual signals from 126 million photoreceptors funnel down to one million ganglion cells that convey at least a dozen representations of a visual scene to higher brain regions.

The Revised Edition calls attention to general principles applicable to all vertebrate retinas, while showing how the visual needs of different animals are reflected in their retinal variations. It includes completely new chapters on color vision and retinal degenerations and genetics, as well as sections on retinal development and visual pigment biochemistry, and presents the latest knowledge and theories on how the retina is organized anatomically, physiologically, and pharmacologically.

The clarity of writing and illustration that made The Retina a book of choice for a quarter century among graduate students, postdoctoral fellows, vision researchers, and teachers of upper-level courses on vision is retained in Dowling’s new easy-to-read Revised Edition.

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front cover of Revertigo
Revertigo
An Off-Kilter Memoir
Floyd Skloot
University of Wisconsin Press, 2014
One March morning, writer Floyd Skloot was inexplicably struck by an attack of unrelenting vertigo that ended 138 days later as suddenly as it had begun. With body and world askew, everything familiar had transformed. Nothing was ever still. Revertigo is Skloot’s account of that unceasingly vertiginous period, told in an inspired and appropriately off-kilter form.
            This intimate memoir—tenuous, shifting, sometimes humorous—demonstrates Skloot’s considerable literary skill honed as an award-winning essayist, memoirist, novelist, and poet. His recollections of a strange, spinning world prompt further musings on the forces of uncertainty, change, and displacement that have shaped him from childhood to late middle age, repeatedly knocking him awry, realigning his hopes and plans, even his perceptions. From the volatile forces of his mercurial, shape-shifting early years to his obsession with reading, acting, and writing, from the attack of vertigo to a trio of postvertigo (but nevertheless dizzying) journeys to Spain and England, and even to a place known only in his mother’s unhinged fantasies, Skloot makes sense of a life’s phantasmagoric unpredictability.

Finalist, Sarah Winnemucca Award for Creative Nonfiction, Oregon Book Awards
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front cover of Rita-Levi-Montalcini
Rita-Levi-Montalcini
a pioneer in neuroscience
Manfredi Toraldo
Dana Press, 2018
Originally written in Italian and now available in English (PDF), this graphic novel celebrates the life and work of neuroscientist Rita Levi-Montalcini, who won the Nobel Prize in Physiology or Medicine for her "discovery of nerve growth factor" in 1986.
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front cover of Romania’s Abandoned Children
Romania’s Abandoned Children
Deprivation, Brain Development, and the Struggle for Recovery
Charles A. Nelson, Nathan A. Fox, and Charles H. Zeanah
Harvard University Press, 2014

The implications of early experience for children’s brain development, behavior, and psychological functioning have long absorbed caregivers, researchers, and clinicians. The 1989 fall of Romania’s Ceausescu regime left approximately 170,000 children in 700 overcrowded, impoverished institutions across Romania, and prompted the most comprehensive study to date on the effects of institutionalization on children’s wellbeing. Romania’s Abandoned Children, the authoritative account of this landmark study, documents the devastating toll paid by children who are deprived of responsive care, social interaction, stimulation, and psychological comfort.

Launched in 2000, the Bucharest Early Intervention Project (BEIP) was a rigorously controlled investigation of foster care as an alternative to institutionalization. Researchers included 136 abandoned infants and toddlers in the study and randomly assigned half of them to foster care created specifically for the project. The other half stayed in Romanian institutions, where conditions remained substandard. Over a twelve-year span, both groups were assessed for physical growth, cognitive functioning, brain development, and social behavior. Data from a third group of children raised by their birth families were collected for comparison.

The study found that the institutionalized children were severely impaired in IQ and manifested a variety of social and emotional disorders, as well as changes in brain development. However, the earlier an institutionalized child was placed into foster care, the better the recovery. Combining scientific, historical, and personal narratives in a gripping, often heartbreaking, account, Romania’s Abandoned Children highlights the urgency of efforts to help the millions of parentless children living in institutions throughout the world.

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