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Biocapital
The Constitution of Postgenomic Life
Kaushik Sunder Rajan
Duke University Press, 2006
Biocapital is a major theoretical contribution to science studies and political economy. Grounding his analysis in a multi-sited ethnography of genomic research and drug development marketplaces in the United States and India, Kaushik Sunder Rajan argues that contemporary biotechnologies such as genomics can only be understood in relation to the economic markets within which they emerge. Sunder Rajan conducted fieldwork in biotechnology labs and in small start-up companies in the United States (mostly in the San Francisco Bay area) and India (mainly in New Delhi, Hyderabad, and Bombay) over a five-year period spanning 1999 to 2004. He draws on his research with scientists, entrepreneurs, venture capitalists, and policymakers to compare drug development in the two countries, examining the practices and goals of research, the financing mechanisms, the relevant government regulations, and the hype and marketing surrounding promising new technologies. In the process, he illuminates the global flow of ideas, information, capital, and people connected to biotech initiatives.

Sunder Rajan’s ethnography informs his theoretically sophisticated inquiry into how the contemporary world is shaped by the marriage of biotechnology and market forces, by what he calls technoscientific capitalism. Bringing Marxian theories of value into conversation with Foucaultian notions of biopolitics, he traces how the life sciences came to be significant producers of both economic and epistemic value in the late twentieth century and early twenty-first.

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Genetics and the Unsettled Past
The Collision of DNA, Race, and History
Wailoo, Keith
Rutgers University Press, 2012

Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present.

Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history.

This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

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Genomes and What to Make of Them
Barry Barnes and John Dupré
University of Chicago Press, 2008
The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it.

For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics­, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. 

Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.
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Genomics with Care
Minding the Double Binds of Science
Mike Fortun
Duke University Press, 2023
In Genomics with Care Mike Fortun presents an experimental ethnography of contemporary genomics, analyzing science as a complex amalgam of cognition and affect, formal logics and tacit knowledge, statistics, and ethics. Fortun examines genomics in terms of care—a dense composite of affective and cognitive forces that drive scientists and the relations they form with their objects of research, data, knowledge, and community. Reading genomics with care shows how each resists definition yet is so entangled as to become indistinguishable. Fortun analyzes four patterns of genomic care—curation, scrupulousness, solicitude, and friendship—seen in the conceptual, technological, social, and methodological changes that transpired as the genetics of the 1980s became the genomics of the 1990s, and then the “post-genomics” of the 2000s. By tracing the dense patterns made where care binds to science, Fortun shows how these patterns mark where scientists are driven to encounter structural double binds that are impossible to resolve, and yet are where scientific change and creativity occur.
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Mestizo Genomics
Race Mixture, Nation, and Science in Latin America
Peter Wade, Carlos López Beltrán, Eduardo Restrepo and Ricardo Ventura Santos, eds.
Duke University Press, 2014
In genetics laboratories in Latin America, scientists have been mapping the genomes of local populations, seeking to locate the genetic basis of complex diseases and to trace population histories. As part of their work, geneticists often calculate the European, African, and Amerindian genetic ancestry of populations. Some researchers explicitly connect their findings to questions of national identity and racial and ethnic difference, bringing their research to bear on issues of politics and identity.

Drawing on ethnographic research in Brazil, Colombia, and Mexico, the contributors to Mestizo Genomics explore how the concepts of race, ethnicity, nation, and gender enter into and are affected by genomic research. In Latin America, national identities are often based on ideas about mestizaje (race mixture), rather than racial division. Since mestizaje is said to involve relations between European men and indigenous or African women, gender is a key factor in Latin American genomics and in the analyses in this book. Also important are links between contemporary genomics and recent moves toward official multiculturalism in Brazil, Colombia, and Mexico. One of the first studies of its kind, Mestizo Genomics sheds new light on the interrelations between "race," identity, and genomics in Latin America.

Contributors. Adriana Díaz del Castillo H., Roosbelinda Cárdenas, Vivette García Deister, Verlan Valle Gaspar Neto, Michael Kent, Carlos López Beltrán, María Fernanda Olarte Sierra, Eduardo Restrepo, Mariana Rios Sandoval, Ernesto Schwartz-Marín, Ricardo Ventura Santos, Peter Wade
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Perspectives on the Human Genome Project and Genomics
Christopher R. Donohue
University of Minnesota Press, 2026

Interdisciplinary voices reflect on some of the most complex and consequential scientific undertakings of our time

Perspectives on the Human Genome Project and Genomics is a groundbreaking volume that examines the pivotal roles of the National Institutes of Health (NIH) and the National Human Genome Research Institute (NHGRI) in the Human Genome Project (HGP) and the development of other major genomics projects. Drawing on newly uncovered archival materials and oral histories from NHGRI, this volume offers a multifaceted narrative of some of the most transformative scientific achievements of the twentieth and twenty-first centuries.

Coeditors Christopher R. Donohue and Alan C. Love bring together a range of perspectives on the HGP’s progress and legacy, as well as other major genomics projects, to explore not only their scientific achievements but also their social and political dimensions. Presenting reflections from historians, philosophers, and sociologists alongside those of key NHGRI scientists like Eric Green, Mark Guyer, and Elise Feingold; experts like Nature editor-in-chief Magdalena Skipper and geneticist Eric Vilain; and scholars of the ethical, legal, and social implications of genomics like Jean McEwan and Joy Boyer, Perspectives on the Human Genome Project and Genomics highlights the international, interdisciplinary collaborations and collective long view that underpinned these genomics initiatives aimed at a better understanding of our basic biology and genetic diseases.

From genomic variation and sequencing technologies to the integration of big data and the influence of ancestry and gender, this book is an essential resource for deepening the discussion of the scientific, historical, and ethical impacts of genomics and a fascinating collection of insights into coordinated science in the making.

Contributors: Rina Bliss, Joy Boyer, Lisa D. Brooks, Michel Dubois, Elise A. Feingold, Adam Felsenfeld, Miguel García-Sancho, Eric Green, Catherine Guaspare, Chris Gunter, Stephan Guttinger, Mark Guyer, Elke Jordan, Jonathan E. LoTempio Jr., Jean McEwen, Jane Peterson, Anya Plutynski, Ramya M. Rajagopalan, Emanuele Ratti, Sahotra Sarkar, Jeffery A. Schloss, Magdalena Skipper, Alexandra Soulier, Thomas Stoeger, Eric Vilain, Kris A. Wetterstrand.

 

Retail e-book files for this title are screen-reader friendly with images accompanied by short alt text and/or extended descriptions.

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The Postgenomic Condition
Ethics, Justice, and Knowledge after the Genome
Jenny Reardon
University of Chicago Press, 2017
Now that we have sequenced the human genome, what does it mean? In The Postgenomic Condition, Jenny Reardon critically examines the decade after the Human Genome Project, and the fundamental questions about meaning, value and justice this landmark achievement left in its wake.

Drawing on more than a decade of research—in molecular biology labs, commercial startups, governmental agencies, and civic spaces—Reardon demonstrates how the extensive efforts to transform genomics from high tech informatics practiced by a few to meaningful knowledge beneficial to all exposed the limits of long-cherished liberal modes of knowing and governing life. Those in the American South challenged the value of being included in genomics when no hospital served their community.  Ethicists and lawyers charged with overseeing Scottish DNA and data questioned how to develop a system of ownership for these resources when their capacity to create things of value—new personalized treatments—remained largely unrealized. Molecular biologists who pioneered genomics asked whether their practices of thinking could survive the deluge of data produced by the growing power of sequencing machines. While the media is filled with grand visions of precision medicine, The Postgenomic Condition shares these actual challenges of the scientists, entrepreneurs, policy makers, bioethicists, lawyers, and patient advocates who sought to leverage liberal democratic practices to render genomic data a new source of meaning and value for interpreting and caring for life. It brings into rich empirical focus the resulting hard on-the-ground questions about how to know and live on a depleted but data-rich, interconnected yet fractured planet, where technoscience garners significant resources, but deeper questions of knowledge and justice urgently demand attention.
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Postgenomics
Perspectives on Biology after the Genome
Sarah S. Richardson and Hallam Stevens, editors
Duke University Press, 2015
Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences.

Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
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Reading in the Postgenomic Age
Race, Discipline, and Bionarrativity in Contemporary North American Literature
Lesley Larkin
The Ohio State University Press, 2025
In Reading in the Postgenomic Age, Lesley Larkin analyzes how writers across literary genres have reckoned with the launch (in the early 1990s) and completion (in 2003) of the Human Genome Project and the ways it has fallen short of its promise to do away with spurious notions of race. Authors such as Margaret Atwood, Octavia Butler, Ruth Ozeki, Rebecca Skloot, Gerald Vizenor, and others demonstrate that genomics is a premier terrain upon which race is being reinscribed and reimagined in both scientific and mainstream contexts. Through construction of alternate genealogies, invention of hybrids, and citation of the textual metaphors replete within genomic discourse, these writers have illuminated the ethical, cultural, social, and political ramifications of genomic research, attuning readers to postgenomic discourses of race and power. At the same time, Larkin contends that literature’s engagement with genomics goes beyond its initial critique to comment self-reflexively on the practices and value of literary studies. Ultimately, she argues that contemporary writers outline a new ethical matrix for reading race in the postgenomic era—and rethinks literary criticism within this new paradigm.
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Revisiting Race in a Genomic Age
Koenig, Barbara
Rutgers University Press, 2008

With the completion of the sequencing of the human genome in 2001, the debate over the existence of a biological basis for race has been revived. In Revisiting Race in a Genomic Age, interdisciplinary scholars join forces to examine the new social, political, and ethical concerns that are attached to how we think about emerging technologies and their impact on current conceptions of race and identity.

Essays explore a range of topics that include drug development and the production of race-based therapeutics, the ways in which genetics could contribute to future health disparities, the social implications of ancestry mapping, and the impact of emerging race and genetics research on public policy and the media.

As genetic research expands its reach, this volume takes an important step toward creating a useful interdisciplinary dialogue about its implications.

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The Trouble with Ancient DNA
Telling Stories of the Past with Genomic Science
Anna Källén
University of Chicago Press, 2025
A thoughtful consideration of the storytelling and science behind ancient DNA discoveries.
 
In recent years, discoveries brought to light through analysis of ancient DNA—or aDNA—have made headlines around the world. While ancient DNA studies may appear to focus on laboratory science and objective results, the findings have also relied heavily on storytelling and can be influenced by political interests.
 
In The Trouble with Ancient DNA, Anna Källén explores how the parameters of genetic science influence the stories we tell about our ancient ancestors, questioning what narratives we can and should take at face value. Through accounts of migrations, warriors, and figures like Cheddar Man, we see enticing and potent narratives that reach far beyond what can be gathered from the scientific study of molecules alone. Rather, by privileging certain narratives and questions—like those about sex or eye and skin color—our stories of ancient DNA are spun around the structure of today’s methodologies, technologies, and popular and political interests. Källén considers how DNA is used to sensationalize stories, how its use poses questions of ethics and care, and who is responsible if stories of ancient DNA are adopted for dangerous political projects.
 
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