According to an early 1990s study, 95 percent of what college students know about Native Americans was acquired through the media, leading to widespread misunderstandings of First Nations peoples. Sierra Adare contends that negative "Indian" stereotypes do physical, mental, emotional, and financial harm to First Nations individuals.

At its core, this book is a social study whose purpose is to explore the responses of First Nations peoples to representative "Indian" stereotypes portrayed within the TV science fiction genre. Participants in Adare's study viewed episodes from My Favorite Martian, Star Trek, Star Trek: Voyager, Quantum Leap, The Adventures of Superman, and Star Trek: The Next Generation. Reactions by viewers range from optimism to a deep-rooted sadness. The strongest responses came after viewing a Superman episode's depiction of an "evil medicine man" who uses a ceremonial pipe to kill a warrior. The significance of First Nations peoples' responses and reactions are both surprising and profound. After publication of "Indian" Stereotypes in TV Science Fiction, ignorance can no longer be used as an excuse for Hollywood's irresponsible depiction of First Nations peoples' culture, traditions, elders, religious beliefs, and sacred objects.

When Lieutenant Uhura took her place on the bridge of the Starship Enterprise on Star Trek, the actress Nichelle Nichols went where no African American woman had ever gone before. Yet several decades passed before many other black women began playing significant roles in speculative (i.e., science fiction, fantasy, and horror) film and television—a troubling omission, given that these genres offer significant opportunities for reinventing social constructs such as race, gender, and class. Challenging cinema’s history of stereotyping or erasing black women on-screen, Where No Black Woman Has Gone Before showcases twenty-first-century examples that portray them as central figures of action and agency.

Writing for fans as well as scholars, Diana Adesola Mafe looks at representations of black womanhood and girlhood in American and British speculative film and television, including 28 Days Later, AVP: Alien vs. Predator, Children of Men, Beasts of the Southern Wild, Firefly, and Doctor Who: Series 3. Each of these has a subversive black female character in its main cast, and Mafe draws on critical race, postcolonial, and gender theories to explore each film and show, placing the black female characters at the center of the analysis and demonstrating their agency. The first full study of black female characters in speculative film and television, Where No Black Woman Has Gone Before shows why heroines such as Lex in AVP and Zoë in Firefly are inspiring a generation of fans, just as Uhura did.