At the 1988 summer session, the internationally famous Marine Biological Laboratory (MBL) at Woods Hole, Massachusetts celebrated one hundred years of pioneering science. During the centennial festivities, many of the world's most renowned biologists assembled at MBL and delivered the Lab's traditional Friday Night Lectures, which as always were extraordinary and memorable. These lectures have been gathered and judiciously edited here by three eminent participants.

Each centennial lecture is dedicated to one or two MBL pioneers, investigators at the forefront of the "new biology" that emerged toward the turn of the century. The MBL often provided an environment that was conducive to revolutionizing the discipline, replacing its largely descriptive and speculative methods with lively analytical and experimental science.

Combining history and current science, each lecture focuses on a subfield of biology. The speakers represented include John Gurdon on developmental biology, Joshua Lederberg on genetics, Torsten Wiesel on neurobiology, and E. 0. Wilson on animal behavior. Benjamin Kamminer provides an account of the work of Albert Szent-Györgyi, capturing his iconoclastic, tenacious, sometimes outrageous nature, as well as his humor and insight. And Gerald Weissmann compares Jacques Loeb and Gertrude Stein--an unlikely pair bound by their common assent to mechanistic materialism.

The history and scientific discovery in these pages should convey for any reader whether biologist, historian, or interested layperson--the excitement of the renowned laboratory and the drama and frustration of biology in the twentieth century.

Harvard University Press is proud to announce the second edition of a widely admired introductory textbook. When first published, Neurons and Networks filled the need for an introductory neuroscience text that is lucid, accessible, authoritative, logically organized, and concise. Avoiding the encyclopedic coverage that makes most neuroscience texts overwhelming, Neurons and Networks focused instead on building the solid foundation of understanding and knowledge required for further study.

The new edition retains the features that made the first edition so attractive: consistent emphasis on results and concepts that have stood the test of time; abundant high-quality illustrations; exceptionally clear explanations of technical terms. Completely revised and enlarged with six new chapters, the second edition of Neurons and Networks is an introduction not just to neurobiology, but to all of behavioral neuroscience. It is an ideal text for first- or second-year college students with minimal college science exposure. It is also an invaluable resource for students in biology, psychology, anthropology, and computer science who seek an accessible guide to a discipline that will be a critically important area of research in the twenty-first century.

John Dowling’s The Retina, published in 1987, quickly became the most widely recognized introduction to the structure and function of retinal cells. In this Revised Edition, Dowling draws on twenty-five years of new research to produce an interdisciplinary synthesis focused on how retinal function contributes to our understanding of brain mechanisms.

The retina is a part of the brain pushed out into the eye during development. It retains many characteristics of other brain regions and hence has yielded significant insights on brain mechanisms. Visual processing begins there as a result of neuronal interactions in two synaptic layers that initiate an analysis of space, color, and movement. In humans, visual signals from 126 million photoreceptors funnel down to one million ganglion cells that convey at least a dozen representations of a visual scene to higher brain regions.

The Revised Edition calls attention to general principles applicable to all vertebrate retinas, while showing how the visual needs of different animals are reflected in their retinal variations. It includes completely new chapters on color vision and retinal degenerations and genetics, as well as sections on retinal development and visual pigment biochemistry, and presents the latest knowledge and theories on how the retina is organized anatomically, physiologically, and pharmacologically.

The clarity of writing and illustration that made The Retina a book of choice for a quarter century among graduate students, postdoctoral fellows, vision researchers, and teachers of upper-level courses on vision is retained in Dowling’s new easy-to-read Revised Edition.