A SCHOLARLY BOOK REPOSITORY
The book is the result of intense bibliographic research and of original documents aimed not just at the examination of Barton’s life and work, but also the examination of today’s perspectives and future work in the field of infectious and “neglected” diseases. The authors address current scientific information on the relevant bacteria Bartonella bacilliformis, besides current research and clinical status of the other Bartonellas, making it a useful and practical text for those studying infectious diseases.
Humans have lived in close proximity to other animals for thousands of years. Recent scientific studies have even shown that the presence of animals has a positive effect on our physical and mental health. People with pets typically have lower blood pressure, show fewer symptoms of depression, and tend to get more exercise.
But there is a darker side to the relationship between animals and humans. Animals are carriers of harmful infectious agents and the source of a myriad of human diseases. In recent years, the emergence of high-profile illnesses such as AIDS, SARS, West Nile virus, and bird flu has drawn much public attention, but as E. Fuller Torrey and Robert H. Yolken reveal, the transfer of deadly microbes from animals to humans is neither a new nor an easily avoided problem.
Beginning with the domestication of farm animals nearly 10,000 years ago, Beasts of the Earth traces the ways that human-animal contact has evolved over time. Today, shared living quarters, overlapping ecosystems, and experimental surgical practices where organs or tissues are transplanted from non-humans into humans continue to open new avenues for the transmission of infectious agents. Other changes in human behavior like increased air travel, automated food processing, and threats of bioterrorism are increasing the contagion factor by transporting microbes further distances and to larger populations in virtually no time at all.
While the authors urge that a better understanding of past diseases may help us lessen the severity of some illnesses, they also warn that, given our increasingly crowded planet, it is not a question of if but when and how often animal-transmitted diseases will pose serious challenges to human health in the future.
When new diseases spread, news reports often focus on wildlife culprits—rodents, monkeys and mpox; bats and COVID-19; waterfowl and avian flu; or mosquitoes and Zika. But, in this urgent and engaging book, we see it often works the other way around—humans have caused diseases in other animals countless times, through travel and transport, the changes we impose on our environment, and global warming. With science journalist Liz Kalaugher as our guide, we meet the wildlife we have harmed and the experts now studying the crosscurrents between humans, other animals, and health.
Herds of buffalo in Kenya, cloned ferrets in Colorado, and frogs shipped worldwide as living pregnancy tests for humans, all help Kalaugher dive into the murky backstories behind wildlife epidemics past and present. We learn that military conflict likely contributed to the spread of rinderpest, or cattle plague, throughout Africa, devastating pastoral communities. That crowded poultry farms may create virulent new forms of bird flu that spill back into the wild. And that West Nile virus—which affects not only birds and humans, but other animals, including horses, skunks, and squirrels—is spreading as global temperatures rise.
Expanding today’s discussions of environmental protection to include illness and its impact, Kalaugher both sounds the alarm and explores ways to stop the emergence and spread of wildlife diseases. These solutions start with a simple lesson: when we protect other animals, we protect ourselves.
The first comprehensive account of the major disease-eradication campaigns from the early twentieth century right up to the present, Eradication places these ambitious goals in their broad historical and contemporary contexts. From the life and times of the American arch-eradicationist Dr. Fred Lowe Soper (1893-1977), who was at the center of many of the campaigns and controversies surrounding eradication in his lifetime, to debates between proponents of primary health care approaches to ill health versus the eradicationists, Nancy Leys Stepan’s narrative suggests that today these differing public health approaches may be complementary rather than in conflict. Enlightening for general readers and specialists alike, Eradication is an illuminating look at some of the most urgent problems of health and disease around the world.
"The algorithms in this book have been developed by Drs. Warren and Mahmoud, as the result of a systematic effort to produce such guides. The book is presented as another in the series "Studies in Infectious Disease Research" and is a most welcome addition, certain to supply a major and hitherto inadequately fulfilled need."—from the Foreword, by Edward H. Kass, M. D., Ph.D
Deaths from infectious diseases continue to take a heavy toll even though there have been spectacular successes in their control over the last thirty years. In the developing regions, five of the ten leading causes of death and disease burden in 1990 were infectious diseases--respiratory infections, diarrhea, tuberculosis, measles, and malaria--while in the developed regions the only infectious disease among the ten leading causes of death in 1990 was respiratory infections.
This volume contains comprehensive data and detailed discussions of the global epidemiologies of twenty-three infectious diseases, including the above-mentioned conditions as well as hepatitis B, meningitis, polio, and tetanus.
The Global Epidemiology of Infectious Diseases will serve as a comprehensive reference for epidemiologists, public health professionals, and tropical disease specialists.
With lessons learned from COVID-19, a world-leading expert on pandemic preparedness proposes a pragmatic plan urgently needed for the future of global health security.
The COVID-19 pandemic revealed how unprepared the world was for such an event, as even the most sophisticated public health systems failed to cope. We must have far more investment and preparation, along with better detection, warning, and coordination within and across national boundaries. In an age of global pandemics, no country can achieve public health on its own. Health security planning is paramount.
Lawrence O. Gostin has spent three decades designing resilient health systems and governance that take account of our interconnected world, as a close advisor to the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and many public health agencies globally. Global Health Security addresses the borderless dangers societies now face, including infectious diseases and bioterrorism, and examines the political, environmental, and socioeconomic factors exacerbating these threats. Weak governance, ineffective health systems, and lack of preparedness are key sources of risk, and all of them came to the fore during the COVID-19 crisis, even—sometimes especially—in wealthy countries like the United States. But the solution is not just to improve national health policy, which can only react after the threat is realized at home. Gostin further proposes robust international institutions, tools for effective cross-border risk communication and action, and research programs targeting the global dimension of public health.
Creating these systems will require not only sustained financial investment but also shared values of cooperation, collective responsibility, and equity. Gostin has witnessed the triumph of these values in national and international forums and has a clear plan to tackle the challenges ahead. Global Health Security therefore offers pragmatic solutions that address the failures of the recent past, while looking toward what we know is coming. Nothing could be more important to the future health of nations.
In The Greatest Killer, Donald R. Hopkins provides a fascinating account of smallpox and its role in human history. Starting with its origins 10,000 years ago in Africa or Asia, Hopkins follows the disease through the ancient and modern worlds, showing how smallpox removed or temporarily incapacitated heads of state, halted or exacerbated wars, and devastated populations that had never been exposed to the disease. In Hopkins's history, smallpox was one of the most dangerous-and influential-factors that shaped the course of world events.
Through a close analysis of four cases from around the world, this book explores prejudice toward groups who are thought to have caused and spread COVID-19: the residents of Wuhan and Black African communities in China; ultra-Orthodox Jewish communities in the United States, United Kingdom, and Israel; African-Americans in the United States and Black/Asian/mixed ethnic communities in the United Kingdom; and White right-wing groups in the United States and Europe. The authors examine stereotyping and the false attribution of blame towards these groups, as well as what happens when a collective is actually at fault, and how the community deals with these conflicting issues.
This is a timely, cogent examination of the blame and xenophobia that have been brought to the surface by the COVID-19 pandemic.
At a time when vaccines are a vital tool in the fight against COVID-19 in all its various mutations, this hard-hitting book takes a longer historical perspective. It argues that globalization and cuts to healthcare have been eroding faith in the institutions producing and providing vaccines for more than thirty years. It tells the history of immunization from the work of early pioneers such as Louis Pasteur and Robert Koch through the eradication of smallpox in 1980, to the recent introduction of new kinds of genetically engineered vaccines. Immunization exposes the limits of public health authorities while suggesting how they can restore our confidence. Public health experts and all those considering vaccinations should read this timely history.
For too long, the theory and practice of infectious disease outbreak response have been the domain of a small number of experienced responders. The COVID-19 pandemic brought global attention to the requirements of effective outbreak response, and the need for preparation across the key pillars. Decisionmakers, early career practitioners, and those in the field now have access to a comprehensive text that brings together evidence-based and practical insights from the best in the business.
Dale Fisher, Professor of Medicine at the National University of Singapore, was chair of WHO’s Global Outbreak Alert and Response Network before and during most of the pandemic. In this massive collaborative effort, he marshals nearly one hundred top public health leaders and experts from the front lines to present thirty-seven chapters on pandemic preparedness and response, drawing heavily on experiences from COVID-19, but also from Ebola, MERS, SARS-1, influenza, and other outbreaks of modern times. The contributors include experts from health ministries and Centres for Disease Control and national public health institutions around the world; from international organizations like the WHO, MSF, IFRC, and UNICEF; and research institutions and various NGOs from dozens of countries, adding to the diversity and richness of the descriptions.
Cutaneous leishmaniasis, transmitted by female sandflies, produces skin lesions of varying size and shape. In Colombia, the insect vector of the disease is native to the same forested environments that have served as the main stage for one of the longest and most violent wars in Latin American history. As a result, the populations most affected by leishmaniasis in Colombia are members of the state army and nonstate armed groups.
Lina Pinto-García explores how leishmaniasis and the armed conflict are inextricably connected and mutually reinforcing. Maraña means “tangle” in Spanish but is also commonly used in Colombia to name the entangled greenery, braided lianas, and dense foliage that characterize the tropical forests where leishmaniasis transmission typically occurs. Pinto-García argues that leishmaniasis and the war are not merely linked but enmarañadas to each other through narratives, technologies, and practices produced by the state, medicine, biomedical research, and the armed conflict itself. All told, Maraña is a passionate study of how war has shaped the production of scientific knowledge about leishmaniasis and access to its treatments in Colombia.
An award-winning genetic researcher who helped contain the Ebola outbreak and a prize-winning journalist reveal what it will take to prevent the next pandemic from spiraling out of control.
As we saw with our response to Ebola and Zika—and are seeing now with the disastrous early handling of the coronavirus COVID-19 outbreak—a lack of preparedness, delays in action, and large-scale system-wide problems with the distribution of critical medical resources can result in lost lives.
Outbreak Culture examines each phase of the 2014 Ebola outbreak in West Africa—one of the largest and deadliest epidemics to date—and identifies factors that prevented key information from reaching physicians. Drawing insights from clinical workers, data collectors, organizational experts, and public health researchers, Pardis Sabeti and Lara Salahi expose a fractured system that failed to gather and share knowledge of the virus and ensure timely containment. The authors describe how much more could have been done by global medical and political organizations to safeguard the well-being of caregivers, patients, and communities affected by this devastating outbreak and they outline changes that are urgently needed to ensure a more effective coordinated response to the next epidemic.
Secrecy, competition, and poor coordination plague nearly every major public health crisis—and we are seeing their deadly consequences play out again. A work of fearless integrity and unassailable authority, Outbreak Culture seeks to change the culture of responders.
This authoritative work is the first to analyze critically the entire range of research and theory on stress in animals and humans, from the earliest studies in the 1930s up to the present day. Herbert Weiner not only documents the many empirical and conceptual advances of recent years, but also supplies a new working definition and classification of stressful experience. He describes the integrated, organismic responses to stressful environmental changes, tasks, and challenges in terms of functional adaptation: the failure of these responses results in injury, ill-health, disease, and death. To examine the coordination between behavior and bodily functions, Weiner reviews current knowledge on how stressful experiences also alter biobehavioral rhythms.
Providing a useful, integrative concept of stress rooted in an understanding of the organism as an interactive communication system composed of many subsystems, Perturbing the Organism will interest a wide range of clinicians and researchers throughout the medical and behavioral sciences.
The John D. and Catherine T. MacArthur Foundation Series on Mental Health and Development
Fortunately, science writer Carl Zimmer is here to guide us. In this compact volume, he tells the story of how the smallest living things known to science can bring an entire planet of people to a halt--and what we can learn from how we've defeated them in the past.
Planet of Viruses covers such threats as Ebola, MERS, and chikungunya virus; tells about recent scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and shares new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and, for all its honesty about the threats, as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a world we all need to better understand.
Fully revised and updated, with new illustrations and a new chapter about coronaviruses and the spread of Covid-19, this third edition of Carl Zimmer’s A Planet of Viruses pulls back the veil on this hidden world. It presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate as long as life endures.
A North Carolina woman dies of a flesh-eating bacterial disease. Thousands of people in West Africa are suffering from cholera. And antibiotics are rapidly becoming less and less effective at fighting what were once mild infections. The biggest threat to the future of human society may not be terrorist attacks or nuclear war, but rather microscopic bacteria. Immunologist Norbert Gualde explains in Resistance the dangers we face from bacterial resistance, asserting that we must confront the reality awaiting us--the next fatal plague may occur sooner than we think.
Over the course of the twentieth century, incredible advances in medicine inspired a utopian belief among many that all common infectious diseases would eventually be eradicated. But Resistance shows that this dream is an impossible one. The book’s riveting narrative reveals how new infectious agents and diseases are being discovered every day and how bacteria previously thought to have been destroyed are returning with a vengeance. Drawing upon the history of past epidemics, Gualde explores how new outbreaks might be predicted and controlled. He also investigates the potentially devastating social and political impact of such public health disasters, particularly in underdeveloped countries in the southern hemisphere. He ultimately argues that the constant interaction between man and microorganisms will inevitably catalyze future epidemics similar to the horrific ones of centuries past.
Global outbreak monitoring and medical research on the human body’s immune system are beginning to produce effective strategies against bacterial resistance. But the most important weapon is awareness of the crisis, and this engrossing and brilliantly translated study will serve as a wake-up call for us all.
2016 CCCC Best Book Award in Technical and Scientific Communication
In the past ten years, we have seen great changes in the ways government organizations and media respond to and report on emerging global epidemics. The first outbreak to garner such attention was SARS (severe acute respiratory syndrome). In Rhetoric of a Global Epidemic, Huiling Ding uses SARS to explore how various cultures and communities made sense of the epidemic and communicated about it. She also investigates the way knowledge production and legitimation operate in global epidemics, the roles that professionals and professional communicators, as well as individual citizens, play in the communication process, points of contention within these processes, and possible entry points for ethical and civic intervention.
Focusing on the rhetorical interactions among the World Health Organization, the United States, China, and Canada, Rhetoric of a Global Epidemic investigates official communication and community grassroots risk tactics employed during the SARS outbreak. It consists of four historical cases, which examine the transcultural risk communication about SARS in different geopolitical regions at different stages. The first two cases deal with risk communication practices at the early stage of the SARS epidemic when it originated in southern China. The last two cases move to transcultural rhetorical networks surrounding SARS.
With such threats as SARS, avian flu, and swine flu capturing the public imagination and prompting transnational public health preparedness efforts, the need for a rhetoric of global epidemics has never been greater. Government leaders, public health officials, health care professionals, journalists, and activists can learn how to more effectively craft and manage transcultural risk communication from Ding’s examination of the complex and varied modes of communication around SARS. In addition to offering a detailed case study, Rhetoric of a Global Epidemic provides a critical methodology that professional communicators can use in their investigations of epidemics and details approaches to facilitating more open, participatory risk communication at all levels.
Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation.
According to veterinarian and journalist Mark Walters, we are contributing to-if not overtly causing-some of the scariest epidemics of our time. Through human stories and cutting-edge science, Walters explores the origins of seven diseases: mad cow disease, HIV/AIDS, Salmonella DT104, Lyme disease, hantavirus, West Nile, and new strains of flu. He shows that they originate from manipulation of the environment, from emitting carbon and clear-cutting forests to feeding naturally herbivorous cows "recycled animal protein."
Since Walters first drew attention to these "ecodemics" in 2003 with the publication of Six Modern Plagues, much has been learned about how they developed. In this new, fully updated edition, the author presents research that precisely pinpoints the origins of HIV, confirms the link between forest fragmentation and increased risk of Lyme disease, and expands knowledge of the ecology of West Nile virus.
He also explores developments in emerging diseases, including a new chapter on flu, examining the first influenza pandemic since the Hong Kong flu of 1968; a new tick-borne infection in the Mid-West; a second novel bird flu in China; and yet a new SARS-like virus in the Middle East.
Readers will not only learn how these diseases emerged but the conditions that make future pandemics more likely. This knowledge is critical in order to prevent the next modern plague.
Malaria control, according to Kamat, has become increasingly medicalized, a trend that overemphasizes biomedical and pharmaceutical interventions while neglecting the social, political, and economic conditions he maintains are central to Africa’s malaria problem. Kamat offers recent findings on global health governance, neoliberal economic and health policies, and their impact on local communities.
Seeking to link wider social, economic, and political forces to local experiences of sickness and suffering, Kamat analyzes the lived experiences and practices of people most seriously affected by malaria—infants and children. The persistence of childhood malaria is a form of structural violence, he contends, and the resultant social suffering in poor communities is closely tied to social inequalities.
Silent Violence illustrates the evolving nature of local responses to the global discourse on malaria control. It advocates for the close study of disease treatment in poor communities as an integral component of global health funding. This ethnography combines a decade of fieldwork with critical review and a rare anthropological perspective on the limitations of the bureaucratic, technological, institutional, medical, and political practices that currently determine malaria interventions in Africa.
In Six Modern Plagues, Mark Jerome Walters offers us the first book for the general reader that connects these emerging health risks and their ecological origins. Drawing on new research, interviews, and his own investigations, Mark Jerome Walters weaves together a compelling argument: that changes humans have made to the environment, from warming the climate to clearing the forests, have contributed to, if not caused a rising tide of diseases that are afflicting humans and many other species.
According to Mark Jerome Walters, humans are not always innocent bystanders to infectious disease. To the contrary, in the case of many modern epidemics, we are the instigators. Six Modern Plagues, a ground-breaking introduction to the connection between disease and environmental degradation should be read by all those interested in their health and the health of others.
As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity.
Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.
Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading.
Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse.
Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.
Duke University Press Scholars of Color First Book Award recipient
In Viral Economies, Natalie Porter draws from long-term research on bird flu in Vietnam to chart the pathways of scientists, NGO workers, state veterinarians, and poultry farmers as they define and address pandemic risks. Porter argues that as global health programs expand their purview to include life and livestock, they weigh the interests of public health against those of commercial agriculture, rural tradition, and scientific innovation. Porter challenges human-centered analyses of pandemics and shows how dynamic and often dangerous human-animal relations take on global significance as poultry and their pathogens travel through global livestock economies and transnational health networks. Viral Economies urges readers to think critically about the ideas, relationships, and practices that produce our everyday commodities, and that shape how we determine the value of life—both human and nonhuman.
The COVID-19 pandemic disrupted some lives more than others. While more than half the world’s population experienced physical restrictions in the wake of the virus, Viral Loads reveals how the international response placed disparate burdens on exploited communities across the globe. Contributors from six continents situate the pandemic within a highly connected yet exceedingly unequal world marked by fragmented communities, austere economies, and unstable governments. Ambitious in its scope, Viral Loads insists that medical anthropology must be part of any future efforts to build a new post-pandemic world.
Viruses are the most abundant biological entities on Earth, and arguably the most successful. They are not technically alive, but—as infectious vehicles of genetic information—they have a remarkable capacity to invade, replicate, and evolve within living cells. Synthesizing a large body of recent research, Michael Cordingley goes beyond our familiarity with viral infections to show how viruses spur evolutionary change in their hosts, shape global ecosystems, and influence every domain of life.
In the last few decades, research has revealed that viruses are fundamental to the photosynthetic capacity of the world’s oceans and the composition of the human microbiome. Perhaps most fascinating, viruses are now recognized as remarkable engines of the genetic innovation that fuels natural selection and catalyzes evolution in all domains of life. Viruses have coevolved with their hosts since the beginning of life on our planet and are part of the evolutionary legacy of every species that has ever lived.
Cordingley explains how viruses are responsible for the creation of many feared bacterial diseases and the emergence of newly pathogenic and drug-resistant strains. And as more and more viruses jump to humans from other animals, new epidemics of viral disease will threaten global society. But Cordingley shows that we can adapt, relying on our evolved cognitive and cultural capacities to limit the consequences of viral infections. Piecing together the story of viruses’ major role within and beyond human disease, Viruses creates a valuable roadmap through the rapidly expanding terrain of virology.
In The White Plague, René and Jean Dubos argue that the great increase of tuberculosis was intimately connected with the rise of an industrial, urbanized society and—a much more controversial idea when this book first appeared forty years ago—that the progress of medical science had very little to do with the marked decline in tuberculosis in the twentieth century.
The White Plague has long been regarded as a classic in the social and environmental history of disease. This reprint of the 1952 edition features new introductory writings by two distinguished practitioners of the sociology and history of medicine. David Mechanic's foreword describes the personal and intellectual experience that shaped René Dubos's view of tuberculosis. Barbara Gutmann Rosenkrantz's historical introduction reexamines The White Plague in light of recent work on the social history of tuberculosis. Her thought-provoking essay pays particular attention to the broader cultural and medical assumptions about sickness and sick people that inform a society’s approach to the conquest of disease.
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