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A frightening new plague. A medical mystery. A pioneering immunologist. In A Plague on All Our Houses, Dr. Bruce J. Hillman dissects the war of egos, money, academic power, and Hollywood clout that advanced AIDS research even as it compromised the career of the scientist who discovered the disease. At the beginning of the worldwide epidemic soon to be known as AIDS, Dr. Michael Gottlieb was a young immunologist new to the faculty of UCLA Medical Center. In 1981 he was brought in to consult on a battery of unusual cases: four formerly healthy gay men presenting with persistent fever, weight loss, and highly unusual infections. Other physicians around the country had noted similar clusters of symptoms, but it was Gottlieb who first realized that these patients had a new and deadly disease. He also identified the defect in their immune system that allowed the disease to flourish. He published his findings in a now-iconic lead article in the New England Journal of Medicine—an impressive achievement for such a young scientist—and quickly became the focal point of a whirlwind of panic, envy, desperation, and distrust that played out against a glittering Hollywood backdrop. Courted by the media, the gay community, and the entertainment industry, Gottlieb emerged as the medical face of the terrifying new epidemic when he became personal physician to Rock Hudson, the first celebrity AIDS patient. With Elizabeth Taylor he cofounded the charitable foundation amfAR, which advanced public awareness of AIDS and raised vast sums for research, even as it struggled against political resistance that began with the Reagan administration and trickled down through sedimentary layers of bureaucracy. Far from supporting him, the UCLA medical establishment reacted with dismay to Gottlieb’s early work on AIDS, believing it would tarnish the reputation of the Medical Center. Denied promotion and tenure in 1987, Gottlieb left UCLA for private practice just as the National Institutes of Health awarded the institution a $10 million grant for work he had pioneered there. In the thirty-five years since the discovery of AIDS, research, prevention, and clinical care have advanced to the point that the disease is no longer the death sentence it once was. Gottlieb’s seminal article is now regarded by the New England Journal of Medicine as one of the most significant publications of its two-hundred-year history. A Plague on All Our Houses offers a ringside seat to one of the most important medical discoveries and controversies of our time.

For too long, argues Richard Harvey Brown, social scientists have felt forced to choose between imitating science's empirical methodology and impersonating a romantic notion of art, the methods of which are seen as primarily a matter of intuition, interpretation, and opinion. Developing the idea of a "cognitive aesthetic," Brown shows how both science and art—as well as the human studies that stand between them—depend on metaphoric thinking as their "logic of discovery" and may be assessed in terms of such aesthetic criteria of adequacy as economy, elegance, originality, scope, congruence, and form.

By recognizing this "aesthetic" common ground between science and art, Brown demonstrates that a fusion can be achieved within the human sciences of these two principal ideals of knowledge—the scientific or positivist one and the artistic or intuitive one. A path, then, is opened for creating a knowledge of ourselves and society which is at once objective and subjective, at once valid scientifically and significantly humane.

Early seventeenth-century Italy saw a revolution in instrumental music. Large, varied, and experimental, the new instrumental repertoire was crucial for the Western tradition—but until now, the impulses that gave rise to it had yet to be fully explored. Curious and Modern Inventions offers fresh insight into the motivating forces behind this music, tracing it to a new conception of instruments of all sorts—whether musical, artistic, or scientific—as vehicles of discovery.

Rebecca Cypess shows that early modern thinkers were fascinated with instrumental technologies. The telescope, the clock, the pen, the lute—these were vital instruments for leading thinkers of the age, from Galileo Galilei to Giambattista Marino. No longer used merely to remake an object or repeat a process already known, instruments were increasingly seen as tools for open-ended inquiry that would lead to new knowledge. Engaging with themes from the history of science, literature, and the visual arts, this study reveals the intimate connections between instrumental music and the scientific and artisanal tools that served to mediate between individuals and the world around them.

Kenneth F. Schaffner compares the practice of biological and medical research and shows how traditional topics in philosophy of science—such as the nature of theories and of explanation—can illuminate the life sciences. While Schaffner pays some attention to the conceptual questions of evolutionary biology, his chief focus is on the examples that immunology, human genetics, neuroscience, and internal medicine provide for examinations of the way scientists develop, examine, test, and apply theories.

Although traditional philosophy of science has regarded scientific discovery—the questions of creativity in science—as a subject for psychological rather than philosophical study, Schaffner argues that recent work in cognitive science and artificial intelligence enables researchers to rationally analyze the nature of discovery. As a philosopher of science who holds an M.D., he has examined biomedical work from the inside and uses detailed examples from the entire range of the life sciences to support the semantic approach to scientific theories, addressing whether there are "laws" in the life sciences as there are in the physical sciences. Schaffner's novel use of philosophical tools to deal with scientific research in all of its complexity provides a distinctive angle on basic questions of scientific evaluation and explanation.

A former United States Poet Laureate, winner of a Pulitzer Prize, and recipient of numerous grants and awards, Mona Van Duyn has been hailed as one of our greatest living American poets. To help broaden and uniquely inform our understanding of Van Duyn’s work, editor Michael Burns has gathered ten essays, a poem, a succinct biographical sketch, and Van Duyn’s own laureate address to the Library of Congress.

In the first section of this collection, poets Maxine Kumin and Carolyn Kizer provide tributes that elucidate the special effect Van Duyn’s poetry has had on their work and thought. Pulitzer Prize–winner Richard Howard contributes a poem that both extols the qualities of Van Duyn’s poems and lyrically places those qualities within her contemporary scene.

The second section contains eight essays exploring aspects as varied as Van Duyn’s penchant for particularity, her remarkable ability to rediscover for us the strangeness of everyday living, and her elegant style, fluid in both free verse and form. Included are contributions from Stephen Yenser, Rachel Hadas, Emily Grosholz, Sidney Burris, Ann Townsend, Michael Bugeja, Wyatt Prunty, and Jane Hoogestraat.

The final section opens with Van Duyn’s witty and incisive overview of the state of poetry in America at the close of the twentieth century. Also included is a short narrative history of Van Duyn’s literary career. Filled with keen prose by distinguished poets and critics, this collection is not only a resounding tribute to one poet’s body of work, but also a timely pulse-taking of the literary scene surrounding Van Duyn’s poetry.

The Red Planet has been a subject of fascination for humanity for thousands of years, becoming part of our folklore and popular culture. The most Earthlike of the planets in our solar system, Mars may have harbored some form of life in the past and may still possess an ecosystem in some underground refuge. The mysteries of this fourth planet from our Sun make it of central importance to NASA and its science goals for the twenty-first century.  

In the wake of the very public failures of the Mars Polar Lander and the Mars Climate Orbiter in 1999, NASA embarked on a complete reassessment of the Mars Program. Scott Hubbard was asked to lead this restructuring in 2000, becoming known as the "Mars Czar." His team's efforts resulted in a very successful decade-long series of missions—each building on the accomplishments of those before it—that adhered to the science adage "follow the water" when debating how to proceed. Hubbard's work created the Mars Odyssey mission, the twin rovers Spirit and Opportunity, the Mars Reconnaissance Orbiter, the Phoenix mission, and most recently the planned launch of the Mars Science Laboratory. 

Now for the first time Scott Hubbard tells the complete story of how he fashioned this program, describing both the technical and political forces involved and bringing to life the national and international cast of characters engaged in this monumental endeavor.  Blending the exciting stories of the missions with the thrills of scientific discovery, Exploring Mars will intrigue anyone interested in the science, the engineering, or the policy of investigating other worlds.
 

With Forms of Discovery, Yvor Winters completes his critical canon. The distinguished poet-critic defines by analysis and example the development of the method that he has called “post-Symbolist.” Starting with the styles of the English Renaissance, Winters discusses at length the felicities and shortcomings of these traditions, the main defect being that sensory imagery was little more than ornament. This sets the problem: to discover a style wherein both the conceptual and the perceptual are given their fullest expression In the work of Charles Churchill, Winters explores the development of a complexly controlled associational procedure. Here is a richly varied conceptual method, though the sensory is still almost totally absent. Churchill’s methods and those of the Renaissance masters are then contrasted with the work of the Romantics, who wrote a great deal about nature without bothering to look at it, and whose most lasting contribution would appear to be pathetically sentimental fallacies. The turn of the century, in France, Britain, and America, sees the beginning of the post-Symbolist methods, while Yeats continues the retrograde movement of the Romantics. It is in the work of poets like Tuckerman, Hardy, Bridges, Stevens, T. Sturge Moore, and Paul Valéry that rational discourse combines richly with the perceptual universe in which we live: the particular perception is enhanced by reference to general concepts, the general given substance by the particular exemplifying it. The post-Symbolist methods result in a poetry that unifies the diverse fields of human experience and employs all aspects of language. Style in Winters’ sense is not simply a way of gracefully combining words. It is the way a man lives, the method or art wherein he discovers to the best of his ability the real nature of the world in which he lives. It is in this sense that Forms of Discovery is a philosophical work, not a miscellaneous collection of essays; this book is, as Winters remarks, “an act of piety, not an act of destruction.”

Widely regarded as the driest place on earth, the seemingly desolate Atacama Desert of Chile is a place steeped in intrigue and haunted by collective memories. This book, based on archival research and the author's personal field experiences, brings together the works of geographers, historians, anthropologists, botanists, geologists, astronomers, novelists, and others to offer a nuanced understanding of this complex desert landscape.

Beginning with the indigenous Atacameño peoples at the southern edge of the Incan empire, the volume moves through five hundred years of history, sharing accounts written by Spanish, French, German, Dutch, British, American, and other travelers—pirates, scientists, explorers, and entrepreneurs among them. The Atacama’s austere landscape hides many secrets, including vast mineral wealth, the world's oldest mummies, and the more recent remains of dissidents murdered by the regime of former Chilean dictator Augusto Pinochet in the early 1970s. Today numerous observatories operate under the Atacama’s clear night skies, astronauts train on the rugged desert floor, and tourists flock there for inspiration.

In addition to a rich set of narratives, the book features 115 images—historical maps, photographs, and natural history illustrations, most in full color—to tell a more complete and compelling story. Imagining the Atacama Desert shows how what was once a wilderness at the edges of empire became one of South America's most iconic regions, one that continues to lure those seeking adventure and the unknown. 
 

A Classic in the History of Exploration, a Judicious Account of the Role of the Cabots in the Discovery of the New World
John Cabot, Giovanni Caboto in his native Italian, led an expedition to the New World in 1497 on behalf of King Henry VII of England. He is considered the first European to explore North America since the Viking voyages five hundred years earlier. Although Cabot’s exact landfall on his first voyage is not known—it could have been Nova Scotia, Newfoundland, or even Maine—his claim for England to this territory countered the Spanish and Portuguese explorations to the south, and changed world history. Cabot made three roundtrips between Bristol, England, and North America, and later, his son Sebastian, made two similar voyages. John and Sebastian Cabot: The Discovery of North America by historian Sir Charles Raymond Beazley was first published in 1898. Its enduring value in addition to its lucid, well-balanced and researched narrative is the author’s detailed history of prior voyages to the North American continent, including those from China and the Pacific Islands as well as those from the realms of mythology. The author also includes all extant references to the Cabots in historical documents.

A series of disruptive, unnerving sounds haunts the fictional writings of Franz Kafka. These include the painful squeak in Gregor Samsa's voice, the indeterminate whistling of Josefine the singer, the relentless noise in "The Burrow," and telephonic disturbances in The Castle. In Kafka and Noise, Kata Gellen applies concepts and vocabulary from film theory to Kafka's works in order to account for these unsettling sounds. Rather than try to decode these noises, Gellen explores the complex role they play in Kafka's larger project.
 
Kafka and Noise offers a method for pursuing intermedial research in the humanities—namely, via the productive "misapplication" of theoretical tools, which exposes the contours, conditions, and expressive possibilities of the media in question. This book will be of interest to scholars of modernism, literature, cinema, and sound, as well as to anyone wishing to explore how artistic and technological media shape our experience of the world and the possibilities for representing it.
 

The twenty-five papers in this volume present current analyses of a variety of data and, more significantly, illustrate the various analytical tools available to linguists in the quest for deeper comprehension of the puzzles, questions, and problems they confront in natural language. The distinguished authors collected here explore interactions between linguistic structure and sound patterns across a diverse set of languages. The integrating theme of the volume is the influence of K. P. Mohanan’s philosophy of inquiry, derived not only from his rich body of diverse work but also from the fresh perspectives and intellectual vitality that he has shared with colleagues and students in a career spanning over three decades.

In the tradition of great American rags to riches stories, Seven Iron Men weaves together the history of how the seven Merritt brothers discovered iron ore on the Mesabi Range. In 1890 they were poised to become one of the wealthiest families in America but lost it all to industrialist John D. Rockefeller.

“The tale of their long and furious quest makes for one of the most melodramatic stories in American history. . . . The Merritts leap from the chronicle in all the colors of life—especially Lon, the king of them all, with his maudlin poetizing, his childlike faith in mankind, and his incredible tropical hat. It is a tale full of thrills, shot with sardonic humors.” —H. L. Mencken, The Nation

“Certainly it is no small contribution to the history of the American people to unfold the tale of the discovery and development of those huge iron deposits of the Mesabi Range flanking much of Lake Superior. To these perhaps quite as much as to any other one factor the country owes its industrial supremacy in the ago of steel.” —New York Herald Tribune

Paul de Kruif (1890–1971) was a microbiologist, served as a contributing editor to Reader’s Digest, and was the best-selling author of Microbe Hunters.

Alan Michael Parker’s latest collection, The Age of Discovery, is a work of enduring beauty, filled with his signature tenderness and surprise. Parker’s interests range from the Psalms to the Internet, from a woman stepping out her window to die to two men trying to learn how to live as they argue in a row-boat. With an eye on some of the greatest love poets (Amichai, Mistral, Neruda), Parker delivers a collection deep in empathy, rigorously attentive, and formally inventive.

We think of bees as being among the busiest workers in the garden, admiring them for their productivity. But amid their buzzing, they are also great communicators—and unusual dancers. As Karl von Frisch (1886–1982) discovered during World War II, bees communicate the location of food sources to each other through complex circle and waggle dances. For centuries, beekeepers had observed these curious movements in hives, and others had speculated about the possibility of a bee language used to manage the work of the hive. But it took von Frisch to determine that the bees’ dances communicated precise information about the distance and direction of food sources. As Tania Munz shows in this exploration of von Frisch’s life and research, this important discovery came amid the tense circumstances of the Third Reich.

The Dancing Bees draws on previously unexplored archival sources in order to reveal von Frisch’s full story, including how the Nazi government in 1940 determined that he was one-quarter Jewish, revoked his teaching privileges, and sought to prevent him from working altogether until circumstances intervened. In the 1940s, bee populations throughout Europe were facing the devastating effects of a plague (just as they are today), and because the bees were essential to the pollination of crops, von Frisch’s research was deemed critical to maintaining the food supply of a nation at war. The bees, as von Frisch put it years later, saved his life. Munz not only explores von Frisch’s complicated career in the Third Reich, she looks closely at the legacy of his work and the later debates about the significance of the bee language and the science of animal communication.

This first in-depth biography of von Frisch paints a complex and nuanced portrait of a scientist at work under Nazi rule. The Dancing Bees will be welcomed by anyone seeking to better understand not only this chapter of the history of science but also the peculiar waggles of our garden visitors.
 

Dazzled by the sight of the vast treasure of gold and silver being unloaded at Seville’s docks in 1537, a teenaged Pedro de Cieza de León vowed to join the Spanish effort in the New World, become an explorer, and write what would become the earliest historical account of the conquest of Peru. Available for the first time in English, this history of Peru is based largely on interviews with Cieza’s conquistador compatriates, as well as with Indian informants knowledgeable of the Incan past.
Alexandra Parma Cook and Noble David Cook present this recently discovered third book of a four-part chronicle that provides the most thorough and definitive record of the birth of modern Andean America. It describes with unparalleled detail the exploration of the Pacific coast of South America led by Francisco Pizarro and Diego de Almagro, the imprisonment and death of the Inca Atahualpa, the Indian resistance, and the ultimate Spanish domination.
Students and scholars of Latin American history and conquest narratives will welcome the publication of this volume.

The scene is a Roman bar, where the narrator tells—in outrageous sonnets—of Columbus’s battle with the Spanish bureaucracy for supplies and ships, of the endless storms that pound the ocean, of the voyagers’ inevitable swindling of the natives, and of Columbus’s final fall from royal favor. After several interruptions and promptings by a skeptical and impatient audience, the narrator comes to the point of his yarn—that genius will sometimes exact a heavy price.

Winner of the Harold Morton Landon Translation Award from the Academy of American Poets